血管紧张素

Objective: To investigate the effects of emodin on the proliferation of cultured rat vascular smooth muscle cell induced by angiotensin II.

中文摘要：目的：观察大黄素对血管紧张素Ⅱ诱导血管平滑肌细胞增殖的影响及机制。

Meanwhile,concentrations of KP and ANP in atrium and aorta of the rats were observed as well.

KP不仅具有和ANP一样的利尿、舒张血管、抑制肾素-血管紧张素系统的作用，还具有抑制心肌Na+-K+-ATP酶的作用〔2〕。

Methods:90patients were randomly divided in to 3groups.Group A was with puerarin.pur injection,Group B wit h puerarin.pur injection plus potass ium magnesium aspartate,Group C with ordinary dosage of digax in.

方法将CHF患者90例随机分为A、B、C三组，均以血管紧张素转换酶抑制剂、倍他乐克及利尿剂作为基础治疗，A组加葛根素注射液静滴，B组予葛根素注射液及门冬氨酸钾镁静滴，C组予地高辛口服。

SC acan turn pneuma fine, add appetite, increase activity and improve color pattern and anischuria of RHR rats.SC didn't have evidence effect on SHR rats'body weight, but can increase RHR rats'body weight. 3.3.3 Find The effect on endothelin、nitrogen monoxidum、atrial natriuretic peptide and renin-angiotensin system of SC .

3.3.3三草降压汤对血浆内皮素、一氧化氮、心钠素及肾素-血管紧张素系统的影响 SC能明显降低SHR、RHR两种高血压大鼠模型血浆ET浓度、升高血浆NO浓度、调整二者的平衡，这可能是其发挥降压作用的重要机制。

AngiotensionⅡand endothelin-1 are two important vasoactive peptide,having powerful vasoconstricting and hemodynamic function,except this,both have nonhemodynamic effects as growth factor to induce proliferation,hypertrophy,to stimulate synthesis of matrix proteins,furthermore,also to inhibit matrix degradation, even to mediate inflammation reaction.

血管紧张素Ⅱ(angiotensinⅡ，AngⅡ)和内皮素1(endothelin1，ET-1)是两个重要的血管活性激素，除了血流动力学作用外，还有非血流动力学作用，如促进细胞增生、肥大，刺激细胞外基质的合成并抑制其降解，介导炎症反应。

The purpose of this study was to compare the vasodilating effects of angiotensin-(1-7) [Ang-(1-7)] on the different vessels and to clarify its mechanisms by using relaxing responses of preconstricted vascular rings.

实验采用兔外周动脉离体标本，在预收缩血管后，用血管紧张素[angiotensin--(1--7)，Ang--(1--7)]舒张血管，比较Ang--(1--7)对外周各血管床的舒张效应并分析其产生机制。

Aim: To study the effects of angiotensin receptor antaganist-valsartan on vascular hypertrophy、vasomotion function and aorta vascular smooth muscle cell EGF precursor mRNA expression in spontaneously hypertensive rats.

目的：本文探讨血管紧张素受体拮抗剂-缬沙坦对自发性高血压大鼠血管结构、功能以及主动脉血管平滑肌表皮生长因子前体 mRNA表达的影响。

Among all persons who finished questionnaire 21.68% were resident physician,36.95% were attending physician, 25.65% were vice chief physician/chief physician; the most common cardiovascular disease in the investigated persons hospitals were angina (55.42%),stroke(38.17%), myocardial infarction(28.70%), heart failure (28.24%), hypertension (28.24%); as for early vascular disease detection methods,57.40% of investigated persons thought artery endothelial function examination,46.72% thought angiography, pulse wave velocity measurement and carotid intima-media thickness measurement were 40.61% and 31.76%;76.49% and 53.89% of the investigated persons thought angiotension converting enzyme inhibitor and statins could revert early vascular disease;96.79% of the investigated persons thought promotion early vascular disease detection strategy could help for reducing total burden of cardiovascular disease in our country;78.47% of the investigated persons thought early vascular disease detection methods should be easily used and non-invasive.

被调查者所在医院最常见心血管疾病顺序分别心绞痛55.42%，脑卒中38.17%，心肌梗死28.70%，心力衰竭28.24%，高血压28.24%；关于血管病变早期检测57.40%的被调查者认为通过动脉内皮功能测定，认为通过血管造影者占46.72%，认为通过脉搏波速度和颈动脉内膜中层厚度测定者分别占40.61%和31.76%；分别有76.49%和53.89%的被调查人群认为血管紧张素转换酶抑制剂和他汀类药物能够逆转早期血管病变；96.79%的被调查者认为推广血管病变早期检测技术有利于降低我国心脑血管疾病总体负担；78.47%的被调查者认为用于推广的早期血管病变检测技术应该是操作方便和无创伤。

Among all persons who finished questionnaire 21.68% were resident physician,36.95% were attending physician, 25.65% were vice chief physician/chief physician;the most common cardiovascular disease in the investigated persons hospitals were angina (55.42%),stroke(38.17%),myocardial infarction(28.70%),heart failure(28.24%), hypertension(28.24%);as for early vascular disease detection methods,57.40% of investigated persons thought artery endothelial function examination,46.72% thought angiography,pulse wave velocity measurement and carotid intima-media thickness measurement were 40.61% and 31.76%;76.49% and 53.89% of the investigated persons thought angiotension converting enzyme inhibitor and statins could revert early vascular disease;96.79% of the investigated persons thought promotion early vascular disease detection strategy could help for reducing total burden of cardiovascular disease in our country;78.47% of the investigated persons thought early vascular disease detection methods should be easily used and non-invasive.

被调查者所在医院最常见心血管疾病顺序分别为心绞痛55.42%，脑卒中38.17%，心肌梗死28.70%，心力衰竭28.24%，高血压28.24%；关于血管病变早期检测57.40%的被调查者认为通过动脉内皮功能测定，认为通过血管造影者占46.72%，认为通过脉搏波速度和颈动脉内膜中层厚度测定者分别占40.61%和31.76%；分别有76.49%和53.89%的被调查人群认为血管紧张素转换酶抑制剂和他汀类药物能够逆转早期血管病变；96.79%的被调查者认为推广血管病变早期检测技术有利于降低我国心脑血管疾病总体负担；78.47%的被调查者认为用于推广的早期血管病变检测技术应该是操作方便和无创伤。

Objective: The purpose of this study is to investigate the relationship between the insertion/deletion polymorphism of the angiotensin- concerting enzyme gene and congenital heat disease and to ques the predisposing gene of congenital heart disease by analyzing the polymorphism of the ACE gene of the patients of congenital heart disease. So that we can intervene earlier and reduce the incidence of congenital heart disease.

目的 通过对先天性心脏病患儿血管紧张与转换酶基因多态性的分析，探讨血管紧张素转换酶基因插入/缺失多态性与先天性心脏病的关系，寻找与先天性心脏病发病有关的易感基因，以便及早进行干预，减少先天性心脏病的发病率。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。