血管紧张素

Results (1)LVMI gradually increased from 5d to 30d in OG (P＜0.01);(2)Counts of intracardiac bFGF immune reaction and bFGF mRNA expression were increased at 5d, were essentially normalized at 30d;(3) Intracardial ACE activity, angiotensin II concentration, ACE protein and ACE mRNA expression were progressively risen from 0.5 h or 4 h to 30 d;(4)LVMI was positively correlated with the level of ACE protein and ACE mRNA expression following 5d.

2OG中心肌bFGF免疫反应特异性染色强度增加，半定量显示5天升高(P＜0.05)，30天基本恢复正常(P＞0.05)；bFGF mRNA表达1天升高(P＜0.05)，其后类似bFGF。(3)心肌血管紧张素转换酶活性和血管紧张素Ⅱ水平在术后0.5小时即升高(P＜0.05)，4小时明显增高(P＜0.01)，峰值在30天；心肌ACE蛋白及ACE mRNA表达均在术后4小时明显增高(P＜0.05或＜0.01)，其后逐渐升高，峰值在30天；5天及其后，LVMI与ACE蛋白及ACE mRNA表达数量呈正相关。

Treatment group was treated with valsartan and control group was treated without drugs such as ACEI or ARBs. Pmax,Pd and LADd,LVDs,LVDd were measured and compared before treatment and 6 months' after treatment. Result: There was significant difference in Pd , Pmax and LADd between treatment group and control group .

治疗组给予缬沙坦治疗，对照组给予非血管紧张素转化酶抑制剂类及非血管紧张素受体拮抗剂类降压药治疗，观察药物治疗6个月前后心电图中的Pmax和Pd及超声心动图中的左房舒张末内径、左室收缩末内径、左室舒张末内径的变化。

Recent eidence obtained in itro suggests that the type 2 Ang II receptor (AT2R) mediates the trophic action of Ang II on adipocyte differentiation and lipogenesis.

最近获得的体外试验研究表明2型血管紧张素Ⅱ受体介导血管紧张素Ⅱ引起的脂肪细胞分化的营养作用及脂肪生成。

Objective: Rennin angiotensin aldosterone system plays a crucial role in the initiation and development of cardiac remodeling. Angiotensin II has multiple physiological effects on the cardiovascular system.

目的：肾素-血管紧张素-醛固酮系统过度活跃在多种心血管疾病的发生、发展中发挥重要作用，血管紧张素Ⅱ作为重要的生长促进因子，对多种组织、细胞的生长具有促进作用，是刺激心肌肥厚的主要因素之一。

This enzyme catalyses the conversion of angiotensin I to angiotensin II in the blood plasma and endothelia and prevents the breakdown of bradykinin.

这种酶催化的血管紧张素一血管紧张素血液中的血浆和内皮二，防止故障的激肽转换。

Activities of chymase and ACE were tested by radioimmunological method. Expressions of phosphoric extracellular signal regulated kinase 1/2 (p-ERK1/2) in hearts were measured by western blot. Results: As compared to the control group levels of GSP, myocardial enzymes and myocardial Ang Ⅱ were much lower in those of APS group.

心肌组织的血管紧张素Ⅱ含量；RT-PCR法检测心肌糜酶和血管紧张素转换酶 mRNA表达；放免法检测chymase和ACE的活性；免疫蛋白印迹法检测心肌磷酸化的细胞外信号调节激酶1/2(p-ERK1/2)含量。

Importantly, activation of the renin-angiotensin system was noted in the triply n/i/eNOS-/- mice, and long-term oral treatment with an angiotensin II type 1 receptor blocker significantly suppressed coronary arteriosclerotic lesion formation and the occurrence of spontaneous myocardial infarction and improved the prognosis of those mice, along with ameliorating the metabolic abnormalities.

重要的一点是我们注重到三重缺陷小鼠的肾素-血管紧张素系统激活，而长期口服血管紧张素II 1型受体阻滞剂可以显著抑制冠状动脉硬化损伤的形成以及自发性心肌梗死的发生，并改善这些小鼠的预后，同时也能改善代谢异常情况。

Endothelin-1 (ET-1) is a potent vasoconstrictive peptide that was isolated initially from the conditioned medium of cultured endothelial cells. It is a pathogenic mediator with a number of deleterious effects, including vasoconstriction, fibrosis, vascular hypertrophy,and inflammation.Atrial natriuretic peptide, angiotensin II and nitric oxide also takes an important role in cardiovascular system.

内皮素-1(endothelia-1，ET-1)是一种由内皮细胞合成和分泌的、具有强烈收缩血管作用和促进细胞增生的血管活性多肽，心钠素(atrialnatriuretic peptide，ANP)、血管紧张素Ⅱ(angiotensin Ⅱ，AⅡ)、NO等在心血管系统功能的调节中也起着重要作用。

Additional｜y, although the polymorphism of angiotensin-converting enzyme liD is related with and cardi disease, the research results in different races, nations even the same race and nation are not exactly the same.

血管紧张素转换酶是肾素一血管紧张素系统的关键酶，其基因I/D多态性在不同种族、不同民族等正常人群中分布存在差异，与某些心脑血管疾病的易感性，严重性及预后相关。

objective to observe the protective effect of qiliqiangxin capsule in rabbit heart ventricle reconstitution of chronic heart failure.methods using the method of giving rabbit abdomen aorta half ligations to build the chronic heart failure model to observe qiliqiangxin capsule the effect to blood flow mechanics index,room wall thickness,heart exponent and heart ventricle reconstitution biochemistry index.results qiliqiangxin capsule could reduce effectively bp,lvsp,lvedp,t wave,improve room wall thickness and heart exponent,reduce angii and alt,all the paramenters ahd notable difference,composed to those of model group (p＜0.05,p＜0.01).conclusion qiliqiangxin capsule can improve the blood flow mechanics change of chronic heart failure rabbit,which has notable inhibitory action on heart ventricle reconstitution which originate from chronic heart failure.inhibition of ang ii,alt of immune nerve endocrine system may be a mechanism of qiliqiangxin capsule.

观察血流动力学、标志心室重构的室壁厚度及心脏指数及肾素―血管紧张素―醛固酮系统相关生化指标的变化。结果芪苈强心胶囊可有效降低血压、左室压、左室末期舒张压、t波，改善室壁厚度和心脏指数，降低血清血管紧张素ii及醛固酮水平，与模型组比较均有显著性差异(p＜0.05，p＜0.01)。结论芪苈强心胶囊可改善慢性心力衰竭兔血流动力学的变化，对慢性心力衰竭引起的心室重构具有显著抑制作用，其机制可能与该药发挥抑制神经内分泌免疫系统rass中angii、ald的水平有关。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。