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血管紧张素

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AIM: To investigate the effect of aminoguanidine on plasma and renal levels of angiogenesis Ⅱ, and to identify the relationship of AGEs with AngⅡ in STZ-induced diabetic rats.

目的: 观察早期应用氨基胍对糖尿病大鼠循环及肾脏血管紧张素Ⅱ水平的影响,探讨其对糖尿病肾脏形态、功能的保护作用及潜在AGEs与AngⅡ之间的作用关系。

AIM:To observe the effects of aortal angiotensin Ⅱlevels and AngⅡ receptor in the hypertensive rat models.

目的:本文应用NO合酶竞争性抑制剂左旋硝基精氨酸诱导大鼠高血压,观察对主动脉血管紧张素Ⅱ和AngⅡ受体的影响。

Objective To investigate the correlation between the functional genetic variations of angiotensin-converting enzyme and Chymase genes and the risk of atrial fibrillation in hypertensive patients with left ventricular hypertrophy. Meth- ods From Dec.

目的 探讨高血压左心室肥厚患者血管紧张素转换酶基因和Chymase基因的多态性与心房颤动的相关性。

To study the function of chymase,the protease inhibitors including Lisinopril,Aprotinin and EDTA,and radioimmunuoassy were used to measure the activities of angiotensin converting enzyme and chymase in the heart tissues of transgenic mice harboring the human heart chymase gene and the controls.

为研究糜酶的功能,本文利用蛋白酶抑制剂Lisinopril、Aprotinin及EDTA结合放射免疫分析的方法同时测定了糜酶转基因小鼠心脏组织中血管紧张素转换酶(angiotensin converting enzyme,ACE)及糜酶样活性。

This provides evidence that angiotensin II plays a pathophysiological role in prothrombotic endocardial remodeling.

这提供的证据表明,血管紧张素II在血栓形成的内膜重构中,扮演了病理生理的作用。

Conclusions— AF and rapid atrial pacing both increase endocardial VCAM-1 expression, which can be attenuated by angiotensin II receptor blockade.

结论——房颤和快速心房起搏均可以提高内膜VCAM -1的表达,其可以被血管紧张素受体II阻滞剂所阻断。

Methods The concentrations of serum PCⅢand angiotensinⅡ were measured by radioimmunoassay in 43 patients with AMI, the serum concentrations of creatine kinase isoenzymes MB also were measured by enzym immounoassay at the same time.

采用放免法检测 4 3例AMI患者血清PCⅢ、血管紧张素Ⅱ(angiotensinⅡ,AngⅡ)水平,酶免疫测定法检测肌酸磷酸激酶同工酶MB水平。

Angiotensin II had stimulatory effect on erythroid progenitors invitro and this effect was mediated through its AT1 receptor.

血管紧张素Ⅱ对脐血红系造血祖细胞有优势扩增作用,且通过其表面的AT1R起作用。

AIM: To investigate the expressions of angiotensin Ⅱ and its subtype 2 receptor (AT2) in the aging progress of rat kidney, especially in gerontic rats.

目的:阐明血管紧张素Ⅱ及其2型受体(AT2)在大鼠肾脏增龄过程中的表达变化,探讨AngⅡ及AT2在肾脏衰老过程中的作用机制。

METHODS: Cultured rat cardiomyocytes were induced to be hypertrophy by angiotensin Ⅱ and norepinephrine. Glucose oxidation rate, glucolysis rate and fatty acid oxidation rate were determined by liquid scintillation counting, and cell apoptosis was detected by TUNEL.

应用血管紧张素Ⅱ(AngⅡ, 0.1mol/L)+去甲肾上腺素(NE 1mol/L)诱导培养大鼠心肌细胞肥大,以同位素液闪计数法测定葡萄糖有氧氧化率、葡萄糖酵解率和脂肪酸有氧氧化率,TUNEL法测定细胞凋亡。

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