血管紧张素

Objective To investigate the expression and pathobiological implications of angiotensin Ⅱ type 1 receptor in development of myocardial fibrosis of rats.

目的 探讨血管紧张素Ⅱl型受体在心肌纤维化中的表达及其意义。

Abstract］ AIM: To investigate the effects of angiotensin II receptor antagonist on remodeling of renal arterioles in hypertension.

摘 要］目的：研究血管紧张素II受体拮抗剂对高血压肾小动脉重建的影响。

He ligand of Tie2 is angiotonin,while the one of Tie1 is unknown until now.

ie1的配体目前还不清楚，Tie2的配体是血管紧张素。

PCI triggers inflammatory reaction at early period after percutaneous transluminal coronary stent implantation, and maintain intimal proliferation and apoptosis on a high level by increasing the levels of angiotonin Ⅱ and activating Fas/FasL system.

支架置入在早期即能够诱发明显的炎症反应，并能通过促使血管紧张素Ⅱ水平增高及Fas-FasL系统激活，使得支架置入后的内膜细胞增殖和凋亡在相当一段时间内维持于高水平。

Armando et al9 showed that intact female mice have higher AT2R expression in the kidney compared with ovariectomized females.

Armando等19人研究显示正常的成年雌鼠比卵巢切除后雌鼠肾脏血管紧张素II受体表达水平高。

This increase in angiotensin II result s in a dramatically increased renal tubular avidity for Na+.

血管紧张素Ⅱ增多导致肾小管对Na+的亲和力大大增强。

This increase in angiotensin II results in a dramatically increased renal tubular avidity for Na+.

血管紧张素Ⅱ增多导致肾小管对Na+的亲和力大大增强。

Abstract］Objective:To investigate the effect of berberine on proliferation of pulmonary artery smooth muscle cellsin rats.

目的：观察小檗碱对血管紧张素Ⅱ诱导的培养大鼠肺动脉平滑肌细胞增殖的影响。

Methods the rabbit arterial smooth muscle cells were cultured ex vivo, cells of 4-7 generation were divided into groups interfered with ang-（1-7）, positive control groupsinterfered with ang-ii(10-6mol/l) and blank control group .cell counting with trypanblau dying and mtt were used to evaluate the growth of cells in different groups and results were compared .

体外培养兔肺动脉平滑肌细胞，鉴定后传代培养，取4～7代细胞，应用不同浓度ang-（1-7）干预，并与血管紧张素-ii(ang-ii，浓度10-6mol/l)、空白组对照。通过台盼蓝染色法细胞计数、四甲基偶氮唑蓝比色法，确定肺动脉平滑肌细胞的生长趋势变化。

This review and our recent studies suggest that:(1) baroreceptor reflex is blunted in heart failure;(2) central angiotensin Ⅱ and reactive oxygen species play an important role in blunted baroreceptor reflex;(3) cardiac sympathetic afferent stimulation and chemoreceptor reflex inhibit baroreceptor reflex; and (4) exercise training normalizes abnormal reflexes in the heart failure state.

本综述及我们近年的研究表明：(1)在心力衰竭状态下压力感受性反射功能明显减弱；(2)中枢血管紧张素Ⅱ和活性氧在压力感受性反射功能失调中发挥关键作用；(3)心交感传入刺激和化学感受性反射能抑制压力感受性反射；(4)适当的运动可以部分纠正异常的心血管反射活动。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。