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Objective To determine whether the angiotensin Ⅱ type Ⅰ receptor gene might be implicated in human essential hypertension.

目的确定血管紧张素Ⅱ的Ⅰ型受体与原发性高血压的关系,探索原发性高血压的发病机理。

This review and our recent studies suggest that:(1) baroreceptor reflex is blunted in heart failure;(2) central angiotensin Ⅱ and reactive oxygen species play an important role in blunted baroreceptor reflex;(3) cardiac sympathetic afferent stimulation and chemoreceptor reflex inhibit baroreceptor reflex; and (4) exercise training normalizes abnormal reflexes in the heart failure state.

本综述及我们近年的研究表明:(1)在心力衰竭状态下压力感受性反射功能明显减弱;(2)中枢血管紧张素Ⅱ和活性氧在压力感受性反射功能失调中发挥关键作用;(3)心交感传入刺激和化学感受性反射能抑制压力感受性反射;(4)适当的运动可以部分纠正异常的心血管反射活动。

This review and our recent studies suggest that:(1) baroreceptor reflex is blunted in heart failure;(2) central angiotensin II and reactive oxygen species play an important role in blunted baroreceptor reflex;(3) cardiac sympathetic afferent stimulation and chemoreceptor reflex inhibit baroreceptor reflex; and (4) exercise training normalizes abnormal reflexes in the heart failure state.

本综述及我们近年的研究表明:(1)在心力衰状态下压力感受性反射功能明显减弱(2)中枢血管紧张素Ⅱ和活性氧在压力感受性反射功能失调中发挥关键作用;(3)心交感传入刺激和化学感受性反射能抑制压力感受性反射;(4)适当的运动可以部分纠正异常的心血管反射活动。

Clinical trials are currently underway assessing the effects of aliskiren combined with an angiotensin receptor blocker on intermediate markers of end organ damage, and long-term end point trials are planned.

目前这些正在进行的临床试验旨在评价阿利吉仑与血管紧张素受体拮抗剂合用时对终末器官损伤的中间标志物的效果及其长期临床终点。

Our study demonstrates that FHL2 is essential in modulating the physical state of vSMCs, which is essential in regulating vascular motor function, says Hata.

我们的研究证实FHL2在调整vSMCs生理状态中是必要的,后者是调节血管紧张性功能的要素。

ACE inhibitors, which are now widely used for the treatment of hypertension and heart failure, not only block the generation of Ang II from Ang I, but also prevent the degradation of bradykinin.

血管紧张素转换酶抑制剂现今被广泛应用于高血压和心脏病的治疗中,不仅可以抑制Ang I 到Ang II 的转化,同时还可抑制BK 的降解。

To investigate the relationship between circulating renin-angiotensin system and finger plethysmography in patients with coronary heart disease treated with external counterpulsation.

观察冠心病患者在体外反搏治疗前后循环血液中肾素血管紧张素系统与指脉的变化,分析它们之间的关系,探讨ECP防治冠心病的机制。

Objective To investigate the changes of hemodynamical parameter in rats with myocardial ischemea and the relationship between the changes and the renin angiotensin system.

目的 观察急性心肌缺血大鼠的血流动力学参数的变化过程及其与肾素-血管紧张素系统的关系。

The promise of these drugs is also connected to the fact that we have begun to understand that rennin may have effects independently on the formation of angiotensin II to the traditional pathways.

之所以说这种新药很有前景还有一部分原因是,我们已经开始懂得肾素对血管紧张素II的形成有一定的作用,且这种作用不依赖于传统的作用途径。

It is very important to the preventions, diagnoses and treatments of diseases, especially the complicated ones.

近年来,国内外学者对妊高征的肾素-血管紧张素系统的相关基因进行了研究。

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