血管收缩的

In the recent 20 years,evidences have proved that endothelial cell barrier function and vascular permeability depend on the endothelial morphologic changes and the formation of intercellular gap. It is thought that change of endothelial contractility is the last congenerous pathway of different signal transduction in permeability changes.

近二十多年来从细胞学水平的研究已证明，内皮细胞形态变化和细胞间缝隙的形成决定了内皮细胞的屏障功能和血管的通透性，内皮细胞收缩性的改变被认为是不同的信号机制导致通透性变化的最后共同通路。

And it is involved in the energy metabolism, cell proliferation, hemogenesis and vessel formation and remodeling.

HIF-1α通过调节多种基因的表达来调节细胞对低氧的适应性反应，是迄今为止发现的唯一的一个在缺氧状态下发挥特异性活性的调节分子，被认为是调节缺氧相关基因表达的关键分子，它同激活蛋白(activated protein 1， AP-1)，核转录因子(nuclear factorκB， NF-κB)和p53等协同作用调节机体对缺氧的反应，其功能涉及能量代谢、细胞增殖、造血作用、血管形成、重塑与收缩等诸多方面。

While the tissue spaces surrounding a few blood vessels wasAl and Fg positive,no Al or Fg positive cells were observed.In antemortem injurygroup,diffuse subarachnoid hemorrhage,cerebral edema,swelling or pyknotic neu-rons could be observed.The axons showed irregular swelling and disconnection at1～3h,marked swelling and disconnection at 6h,and retraction ball at 15h whichwas more remarkable at 24h after injury.The space between myelin sheaths andaxons was increased at 3～6h after injury.Tortuous and wavelike myelin sheathswhich adhered on axons incompletely,or even peeled off could be found from 15hto 24h after injury.Perinuclear lysis of Nissl bodies began at 24h after injury.Thenumber of GFAP positive cells in cerebrum and brain-stem increased significantlyfollowed by decrease,and then increased again,but the time courses of the changesin different areas of brain were not same.Al and Fg positive neural cells,mainlysurrounded blood vessels,with diffuse or peripherally distributed positive matter incytoplasm could be observed at 0.5h after injury.The number of Al or Fg positivecells and the intensity of immunoreaction increased with the time of injury.The areaof SYN positivity in medulla oblongata and pons decreased notably 3～6h afterinjury,then return to normal levels and continued to 24h after injury.

生前损伤组，可见广泛蛛网膜下腔出血，脑组织水肿，神经细胞肿胀，晚期神经元固缩；伤后1～3h见部分神经轴突不规则增粗、断裂，伤后6h断端膨大，伤后15h可见收缩球，至伤后24h更为明显；伤后3～6h可见部分神经髓鞘与轴突之间的间隙增宽，伤后15h髓鞘明显曲折，不完全附着在轴突两侧，甚至剥脱，持续到伤后24h；核周尼氏体减少在伤后24h才开始出现；同一部位的GFAP阳性细胞数目随损伤时间发生改变，先增多（最早在伤后0.5h），达到高峰后减少，其后又有增多趋势，但不同部位的GFAP阳性细胞数目增减的时间过程不尽相同，同时，大脑中的GFAP阳性细胞数目也有改变；伤后0.5h，可在脑干组织中见到Al和Fg阳性神经细胞，主要位于血管周围，阳性物在胞浆中呈弥散性分布，但部分细胞的阳性物仅分布于靠近胞膜的胞浆中而呈环状，随损伤时间延长，阳性细胞数目增多，反应强度增加；伤后3～6h，延髓及桥脑中的SYN阳性物面积减少，其后恢复到正常水平，并持续到伤后24h。

The heart is a hollow, muscular organ in vertebrates responsible for pumping blood through the blood vessels by repeated, rhythmic contractions, or a similar structure in annelids, mollusks, and arthropods.

英文版的这个句子概述的很出色，另外中国大百科全书的首句是血液循环的动力器官﹐心脏的自动节律性收缩，推动血液在循环系统的各种血管中环流﹐使机体各组织﹑器官能不断地吐故纳新﹑新陈代谢。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新