血管内膜

The vascular adventitia is involved in the pathological process of intimal hyperplasia, and oxidative stress caused by increased NADPH oxidase activity may be one of the mechanisms.

血管外膜参与了内膜病变形成的病理过程；NADPH氧化酶活性升高导致的氧化应激可能是外膜损伤致内膜病变的机制之一。

DPE10 and DPE12 were tested for their antagonistic effect on AA-induced capillary contractions of human endometrium implanted in hamster cheek, pouch.

利用金地鼠颊囊小窗移植人子宫内膜的方法初步观察AA对内膜血管的作用及DPE10和DPE12的影响。

Doxy treatment significantly reduced intimal SMCs proliferation from 62.76%±1.02% in the controls to 43.23%±1.06% at 7 days after injury (P.01). CONCLUSION: Doxy treatment inhibits the activity of MMPs, the SMCs proliferation of intimal, neointimal hyperplasia and vascular remodeling, suggesting that Doxy treatment is useful in preventing restenosis after PTCA.

强力霉素可以显著降低血管损伤后MMPs活性，抑制内膜平滑肌细胞的增殖、新生内膜增生以及管腔重构，提示它可能具有防治PTCA术后再狭窄的作用。

Doxy treatment inhibits the activity of MMPs, the SMC proliferation ofintimal, neointimal hyperplasia and vascular remodeling which suggesting Doxy treatmentbe useful in preventing restenosis after PTCA.

用球囊扩张法可成功建立大鼠颈总动脉损伤膜型；Doxy 可以显著降低血管损伤后 MMPs 活性，抑制内膜 SMCs 的增殖、新生内膜增生以及后期的管腔重构，提示它可能具有防治 PTCA 术后再狭窄的作用。

The results of experiment demonstrate:GuiFu and LiQi capsule can lower the content of ER and PR in ectopia endometrium;raise the activity of NK cells;restrain the generation of VEGF.

实验研究显示：桂附胶囊及理气胶囊能够降低子宫内膜异位症大鼠外周血中E2、P水平，降低异位内膜ER、PR的含量；提高NK细胞活性；抑制血管内皮生长因子的生成。

MAIN OUTCOME MEASURES: Integrality of transplanted vessels, intimal thickness and nitric oxide synthase activity in the intima.

主要观察指标：静脉移植段血管内皮的完整性、内膜厚度及内膜一氧化氮合酶活性。

Results Four weeks after transplantation, fluorescence-labeled cells were found in the media, neointima and on the luminal surface of injured segments.

结果：术后4周，荧光显微镜下，在血管中膜、新生内膜层和内膜表面均可见荧光标记的细胞。

Decidual tissue is a very complex and highly concordant tiny environment between mother and embryo during pregnancy, which is constituted of the variety cells such as extravi11ous trophoblast,endometrium cells, bone marrow cells, decidua l microphage,T cells and a few B cells and so on.

正常蜕膜组织是母-胎界面间一个非常复杂而又高度协调的微环境，它由多种细胞如侵袭至蜕膜的绒毛外滋养细胞(extravi11ous trophoblast，EVT)、子宫内膜源性细胞(如上皮细胞和血管内皮细胞)、骨髓源性细胞(如大颗粒淋巴细胞、蜕膜巨噬细胞、T细胞和少许B细胞)构成，这些细胞以及由这些细胞、母体和胎儿所分泌到蜕膜的细胞因子共同形成了母-胎间信息交流的平台，并对胚胎滋养细胞"有控性"侵袭、子宫内膜的免疫容受性、蜕膜化和胎盘的形成进行精细的调控。

There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.

人及哺乳动物体内有四种结构及药理学性质略有差异的异物体，分别为ET-1、ET-2、ET-3、ET-β，而在人主要是ET-1，在生理条件下，ET-1在血浆中含量较低，约为5ng〓，故ET-1不是一个循环激素，而是局部合成释放，局部起作用的活性物质，半衰期约1小时，ET-1是目前已知的最强的血管收缩剂，对静脉的作用比动脉强，在血管床，ET受体有A、B两型，A型主要分布在平滑肌细胞，B型主要分布在内皮细胞，它可以通过旁分泌途径刺激内膜增生，具有有丝分裂原效应，可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩，使静止期SMC进入增殖期，还可以通过信号传导途径，与bFGF、GTF-β、PDGF等生长因子协同作用，起共有丝分裂原作用。

Supplementation of folate in diets may reduce hyperhomocysteinemia induced by excess intake of methionine and decrease the expression of NF-κBP65 protein and monocyte chemoattractant protein-1 (MCP-1) in carotid common artery after balloon angioplasty, These data show that Hcy may exacerbate neointima hyperplasia after denuding injury by increasing the expression of inflammatory factors via the activation of NF-kB, Folate can reverse the effect of Hcy on the activation of NF-κB and the expression of MCP-1, an effect of preventing the restenosis postangioplasty.

而Hcy有可能通过激活核转录因子通路增加损伤血管组织炎症因子的表达而加重血管球能损伤后新内膜的过度增生过程，叶酸能对抗Hcy的上述作用，对高同型半胱氨酸血症引起的血管成形术后再狭窄可能有一定的预防作用。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。