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RESULTS: Stent materials play an important role in reducing inflammatory reaction and restenosis following stent implantation. As a medical material for humans, the features of stent should be meet the requirements of reliable distensibility, mechanical persistence, good flexibility and geometrical stability, possible small diameter, excellent blood compatibility, as well as good corrosion resistance. All of these depended on the mechanical and physical features of materials.

结果:支架材料的选择在减少机体炎症反应的强度和持续时间,减少支架置入后血管内再狭窄的发生起着重要的作用,作为人体医用材料,对支架各方面性能都提出了很高的要求,包括可靠的扩张性和力学持久性、良好的柔韧性和几何稳定性、尽可能小的外径,优异的血液相容性和耐蚀性,而支架上述特性都依赖于材料的力学和物理特性。

As a medical material for humans, the features of stent should be meet the requirements of reliable distensibility, mechanical persistence, good flexibility and geometrical stability, possible small diameter, excellent blood compatibility, as well as good corrosion resistance.

结果:支架材料的选择在减少机体炎症反应的强度和持续时间,减少支架置入后血管内再狭窄的发生起着重要的作用,作为人体医用材料,对支架各方面性能都提出了很高的要求,包括可靠的扩张性和力学持久性、良好的柔韧性和几何稳定性、尽可能小的外径,优异的血液相容性和耐蚀性,而支架上述特性都依赖于材料的力学和物理特性。

Large numbers of experiments internal and external had confirmed both direct current and square pulse of distal end cathodal could improve peripheral nerve regeneration, because it could speed up transmigration, creeper, growth and development of cell Schwann, derivate growth of nerve fiber; it also increased blood capillary of epineurium, brood blood vessel, amendment ischemic of impaired nerve, it still could accelerate Wallerian

国内外大量的基础实验及临床研究都证实远端负极电流的直流电场及脉冲电场等均有促进周围神经再生的作用,认为其可加速Schwann细胞的游走、爬行及生长发育,诱导神经纤维的生长;电刺激还能促使神经外膜毛细血管数量增多,扩张血管,改善神经损伤段缺血状态,并加速Wallerian变性及崩解组织的清除,为Schwann细胞发育和髓鞘化过程提供充足的能量与物质,同时为神经轴突的再生提供良好的内环境;在神经断端出现瘢痕或神经瘤时,电刺激可增加神经纤维穿越瘢痕的能力。

Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide,又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物,主要成分是倍半萜烯内酯,西方国家较为常用,主要用于治疗皮肤感染、风湿病和偏头痛,但近年来发现小白菊内酯能调控细胞内多种信号途径,如抑制巨噬细胞中脂多糖诱导的Cox,肿瘤坏死因子α和白细胞介素-1的表达,能抑制人单核细胞中iNOS的表达,能抑制Hela细胞中NF-κB的活性,抑制肿瘤细胞的生长,同时能减轻心肌缺血再灌注损伤等,但小白菊内酯在VSMC中的干预研究目前国内外非常罕见,为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制,我们进行了一些研究。

In plants , NO has recently been demonstrated to be involved in the regulation of growth and development in the response to abiotic and biotic stresses and it is a key signal messenger in disease resistance in plants. More important , it has been found that NOs function in plant is similar to the traditional phytohormone , so it is forecasted to be a new type of hormone in plant.

近年来的研究发现,它不仅在血管松弛、神经传导以及先天性免疫反应等动物生理代谢过程中是一种关键的第二信使,而且在植物中也起着非常重要的作用,是植物生长和发育的调节分子,能够对生物性和非生物性的胁迫作出反应,并且在植物体的抗病防御反应中也是一种重要的信号物质;更重要的是,近年来发现NO与各种植物激素的功能都有着重叠,因此有人预测NO可能是植物体内的一种新型激素。

Therefore, the purpose in this study is to observe the change of blood vessel endothelium function and cytokine (tumor necroses factor-α TNF-α, interleukin-6 IL-6) and to investigate the mechanism of Carvedilol improve cardiac function in the patients with CHF.

本实验通过观察CHF患者血管内皮功能和细胞因子:肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、白介素-6(interleukin-6,IL-6)的改变,以及使用卡维地洛后CHF患者这两方面的变化与心功能的改善的相关性,并探讨卡维地洛对CHF改善心功能的可能作用机制,为卡维地洛治疗慢性充血性心力衰竭提供临床依据。

Histologically, the seminiferous tubules contained numerous Sertoli cells and more Sertoli-spermatozoa complexes, accompanied by the depletion of Leydig cells with deeply stained nuclei. Mature spermatozoa were stored up in the epididymis, but only a few in the efferent ducts. In the second place was testicular atrophy(32/120; 26.7%). The seminiferous tubules showed moderate to severe inactivity of spermiogenesis with evidence of only spermatogonia, spermatocytes and Sertoli cells. The Leydig cells were obviously decreased in numbers associated with decrease of lipid droplets in their cytoplasms. Testicular hypoplasia was the third disorders(22/120; 18.3%). Only a few spermatogonia and Sertoli cells appeared without any spermiogenesis. The associated changes was decreased in Leydig cells and fibrous hyperplasia in the interstitium.Epididymal stones were sometimes found(12/120; 10%). Grossly, yellowish-white nodules with various sizes and firm in consistency were observed in the epididymis and the front efferent ducts. Microscopically, the epididymal ducts were dilated with voluminous spermatozoa storage, even showed calcification in severe cases. The deposited calcium salts were stained positively by Von Kossa and Alizarin red methods.Amyloidosis was also detected in 10 roosters(8.3%). Eosinophilic, homogeneous, amyloid-like substances were deposited mainly in the testicular interstitium and the periphery of blood vessels. These substances showed positive reaction by Congo red staining. Five roosters(4.2%)had Marek's lesions in the testis, epididymis and peripheral nerves with infiltration of pleomorphic lymphocytes. Only one case showed epithelial necrosis of seminiferous tubules accompanied by fibrous proliferation in the interstitium.

结果发现,在总共搜集的120个病例中,其中因年老所导致的产精力不佳为最多,占38例(31.7%),於镜下可见大量精虫黏附於Sertoli cell的表面,并可见Sertoli cell数量明显增多而Leydig cell明显减少,且其细胞核呈现浓染的现象,而在其副睪中仍可见到成熟精虫蓄留於管腔中,但在其输精管内却只有少量精虫存在;其次为睪丸萎缩,占32例(26.7%),镜下可见中度至重度无造精作用,其生精小管中只见到精母细胞、精原细胞及Sertoli cell存在,但Leydig cell数量明显减少且其细胞质内的脂质也明显减少;睪丸发育不全,占22例(18.3%),於生精小管内只见到精母细胞及少量Sertoli cell存在,不见造精细胞分化,於生精小管间质可见Leydig cell减少并伴随结缔组织增生;副睪结石,占12例(10%),肉眼下可在副睪及输精管前段见到黄白色大小不一的结节,触感坚硬,於镜下可见副睪管扩张并有大量成熟精虫蓄积,严重时可见钙化现象,以Von Kossa及茜素红染色均呈阳性反应;类淀粉沉著症,占10例(8.3%),镜下在睪丸间质及血管周围可见粉红均质样的物质沉积,以刚果红染色成阳性反应;马立克病,占5例(4.2%),镜下可在睪丸、副睪实质及周边神经内均可见到嗜碱性大小不一的淋巴样细胞浸润;睪丸坏死,占1例(0.8%),镜下可见生精小管上皮细胞坏死脱落及间质结缔组织增生。

Statistical data of VEGF grading scores showed that its expression was not significantly related to the size and location of glioma, sex, and age of patients, but closely related to the glioma gradings. The expression of TF was positively correlated with that of VEGF, suggesting that TF might participate in the anigogenesis of gliomas, and provide proper environment for the growth of gliomas through its coagulant effect.

根据VEGF分级计数统计学分析,显示VEGF表达与肿瘤的大小、部位及患者性别、发病年龄等临床因素无显著相关性,而与肿瘤的组织学分级密切相关。3、胶质细胞瘤中TF与VEGF的表达正相关,TF可能参与了肿瘤血管的生成过程,并通过其促凝血活性作用为胶质瘤的生长创造适宜的内环境。

Therefore with the match of Pre-Tang names of the five notes of the pentatonic scale corresponding roughly to do re mi sol la with the relations between the five elements including Wood, Fire, Earth, Metal, and Water and the function of organs, ideology of body function adjustment and clinical experience from the psychological experts, we specially designed some music with the Hui note to take direct effect on the limbic system and reticular system through the music wave to cause new focus of excitation on reticular system, unblock the blood vessels of heard blood pipes and quicken the waste elimination from the body for physical and emotional regulation.

为此,我们根据中医学界提出运用五音配以五行与人体的脏腑功能相联系,以调整人体功能的理念,同时结合心理专家的临床经验,专门编辑了一些徴调式的乐曲,通过乐曲的声波直接影响人体大脑边缘系统和脑干网状系统,使大脑皮层出现新的兴奋灶,令心脏血管的血脉畅通,加速排除体内废物,从而起到调节身心的作用。

The metabolism of plasma ANP in lung increases in patients with left to right shunt C.H.

①左向右分流的先心病患者血浆ANP在肺部的代谢量增加,可能用于发挥其扩张血管、支气管等作用,但在不同程度肺高压时,其代谢量有差异,提示ANP在肺部的代谢可能与肺高压的形成有一定的关系。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。