血管作用的

Isabellina producing γ-linolenic acid, the number of the chromosomes and the size of genome of M.

深黄被孢霉是毛霉目中具有重要经济价值的丝状真菌，因其产生γ—亚麻酸(γ—Linolenic acid，GLA)，而γ—亚麻酸作为人体必需的不饱和脂肪酸，对人体的激素调节及脂肪酸代谢发挥着重要的生理作用，尤其它在心血管疾病、糖尿病以及癌症等方面的医疗价值而成为学术界研究的热点。

This high-density lipoprotein the role of the United States because of the Brown and Augustan found through research, and HDL in the blood vessel wall and blood can excess cholesterol and other "blood-fouling" seize the dissolved excreted by the liver break down.

这种高密度脂蛋白的作用，是美国的布朗和古斯坦因通过研究实验发现的，血液中的HDL能把血管壁上和血中多余的胆固醇等"血垢"抓住溶解经肝脏分解排出体外。

Potential applications of the company's DNA delivery technology include DNA vaccines for infectious diseases or cancer, in which the expressed protein is an immunogen; cancer immunotherapeutics, in which the expressed protein is an immune system stimulant; and cardiovascular therapies, in which the expressed protein is an angiogenic growth factor.

潜在的应用，该公司的DNA给药技术，包括DNA疫苗，为感染性疾病或癌症，其中所表达的蛋白是一种免疫；癌症免疫疗法，其中所表达的蛋白是一种免疫系统的刺激作用；心血管治疗药物，其中所表达的蛋白质一种血管生长因子。

The dose-response curve of histamine was shifted parallely to the right. pA2 was 9.34±0.61. The guinea-pigs were effectively reduced the rate of histamine induced death, decreased reaction extent of shock (P＜0.01) and prolonged latency period of shock (P＜0.05) by orally administered cetirizine ranged from 0.1, 0.2 and 0.4 mg.kg-1. The capillary permeability to intracutaneous injection of histamine was potently inhibited by orally administered cetirizine ranged from 0.0625 to 0.25 mg.kg-1 in mice, blue area obviously decreased (P＜0.01), and dose-response curve existed obviously. In which the effect of these dosage groups were superior to the group of chlorphenamine.

结果：西替利嗪3×10-8～3×10-7mol.L-1可剂量依赖性地对抗组胺引起的肠肌收缩，使组胺的量效曲线平行右移，pA2为9.34 ± s 0.61，西替利嗪0.1，0.2及0.4 mg.kg-1口服给药时，能明显减轻豚鼠静脉注射组胺所致休克反应的严重程度(P＜0.01)，并可延长豚鼠惊厥反应的潜伏期及降低死亡率(P＜0.05)，西替利嗪0.0625～0.25 mg.kg-1口服给药可显著对抗组胺引起的小鼠皮肤血管通透性的增高，使蓝染面积显著缩小(P＜0.01)，且存在明显的量效关系，3个剂量组的作用均优于氯苯那敏组。

AGEs is not only the products of diabetes, but also act as one of medium, can induce extensive abnormal reaction in cells and tissue such as unreasonable expression of growth factor, accumulation of extracellular matrix, regulation dysfunction of blood vessel, etc.

AGEs不仅仅是糖尿病的并发产物，还可能充当了一种介质作用，在细胞和组织上启动广泛不正常的反应如生长因子不适当地表达、细胞外基质的积聚、血管调节功能障碍以及死亡通道的启动。

Chronic and persistent hypertension will activate circulatory and focal rennin-angiotensin-aldosterole-system, which plays an important role in hypertension development and target organ detriments.

高血压时持续的压力负荷增加可激活一系列神经-体液因子，如循环和局部的肾素-血管紧张素-醛固酮系统在高血压的发生、发展和靶器官损害过程中具有重要的作用。

HIF-1α is an oxygen-regulated protein and is recognized as a positive factor to tumorigenesis. During nomoxia, HIF-1α is rapidly hydroxylated by prolyl hydroxylase then goes into 26S proteasome degradation pathway. During hypoxia, HIF-1α accumulates and dimerizes with HIF-1β to transactivate hypoxia-responsive gene expression.

中文摘要缺氧诱导性因子-1α(HIF-1α)为一种对於氧分压敏感的转录因子，在正常氧分压下HIF-1α很快就被prolyl hydroxylase氢氧化进入26S蛋白酶体降解，当细胞处理缺氧环境时HIF-1α会累积并与HIF-1β形成复合物进行转录活化的作用；HIF-1α所调控的基因包括影响能量供给、细胞生长、血管新生等，被认为在肿瘤发育过程扮演促进者的角色。

HIF-1α is an oxygen-regulated protein and is recognized as a positive factor to tumorigenesis. During nomoxia, HIF-1α is rapidly hydroxylated by prolyl hydroxylase then goes into 26S proteasome degradation pathway. During hypoxia, HIF-1α accumulates and dimerizes with HIF-1β to transactivate hypoxia-responsive gene expression.

缺氧诱导性因子-1α(HIF-1α)为一种对於氧分压敏感的转录因子，在正常氧分压下HIF-1α很快就被prolyl hydroxylase氢氧化进入26S蛋白酶体降解，当细胞处理缺氧环境时HIF-1α会累积并与HIF-1β形成复合物进行转录活化的作用；HIF-1α所调控的基因包括影响能量供给、细胞生长、血管新生等，被认为在肿瘤发育过程扮演促进者的角色。

The cytotoxicity of NO has a relevant role in apoptosis of endothelial cells induced by angiotensin Ⅱ,and can increases the activity of PARP.

NO含量增加导致的细胞毒性在血管紧张素Ⅱ引起内皮细胞的凋亡中有着重要的作用，在这一过程中PARP活性的变化是先上升后下降。

Cellular growth, constrictions function and free Ca2+ in cultured pulmonary artery smooth muscle cells were measured by the methods of MCT, morphometry and calcium fluorescent probe Fura 2-Am.

肺动脉和体动脉不同，对5-HT的缩血管效应比对去甲肾上腺素的更敏感。对5-HT在不同原因形成的肺动脉高压中的作用要做具体分析。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。