血管作用的

Objective To investigate the application of anterolateral thigh fasciocutaneous flap on abdominal chronic ulcer,and provide evidence for its clinical use. Methods From Oct 2005 to Dec 2008,5patients with abdominal ulcer caused by different reasons were repaired with anterolateral thigh fasciocutaneous flap, the flap pedicled with rami descenden of lateral circumflex femoral artery was designed according to the size of abdominal defect,the vessel pedicle was dissociated adequately, the flap was transferred to the abdominal wound under appropriate tension through tunnel, the donor site was sutured directly or repaired with skin-grafting. Results The anterolateral thigh fasciocutaneous flap survived well in all 5 patients,there were no other complication such as skin necrosis.

目的：探讨股前外侧皮瓣在下腹部慢性溃疡中的作用，为其临床应用提供依据；方法：2005年10月～2008年12月间，对5例不同原因引起的下腹部慢性溃疡患者进行修复，术前根据腹部组织缺损的大小设计以旋股外侧动脉降支为血管蒂的岛状股前外侧皮瓣，充分游离血管蒂部，在合适张力下经过皮下或开放隧道将皮瓣带蒂转移至下腹部创面，供区直接缝合或植皮修复。

These results suggest that the inhibitoryeffect of sevoflurane on Ang II-induced vasoconstriction is,at least in part, caused by the inhibition of the p44/42 MAPK-mediatedsignaling pathway.

这一结果表明：七氟醚对於血管紧张素 II 介导的血管收缩的抑制作用，至少部分是由於对 p44/42 MAPK 介导的信号通道的抑制引起。

Therapeutic angiogenesis has been studied widely in the treatment of vascular insufficiency. VEGF is a potent and specific angiogenic factor .

治疗性的血管生成在许多缺血性疾病中研究的较多，其中VEGF促血管生成作用的研究是最令人关注的项目。

After injury 5d-7d, the protein expressed strengthly. Conclusion The stage of the VEGF expression at maxillofacial blast injury is similar to the angiopoietic stage during wound healing, and the Flt-1 expression is also occurring at that period.

VEGF在颌面部爆炸伤后的表达与创伤愈合过程中新生血管形成的时间相似，其受体Flt-1的表达也多发生于此时期，说明VEGF参与调节了创伤愈合过程中的血管再生阶段，对毛细血管的发生有积极促进作用。

After injury 5d-7d, the protein expressed strengthly. Conclusion The stage of the VEGF expression at maxillofacial blast injury is similar to the angiopoietic stage during wound healing, and the Flt-1 expression is also occurring at that period. It illustrates that VEGF take part in angiogenic cascades of traumatic wound healing and product auxo-action to the regeneration of blood vessel.

VEGF在颌面部爆炸伤后的表达与创伤愈合过程中新生血管形成的时间相似，其受体Flt-1的表达也多发生于此时期，说明VEGF参与调节了创伤愈合过程中的血管再生阶段，对毛细血管的发生有积极促进作用。

VSMCsstruction changes and vas wall incrassation have the resembled represent indifferent type hypertension, namely, the result of VSMC growth and vasremodeling.

VSMC结构的变化及血管壁肥厚在不同类型的高血压表现都较为相似，即通过VSMC生长和血管壁&重塑&共同作用的结果。

Among those aggresive growth,poor differentiated,with lymphy node or liver metastased,the presence of MMP-1 were significantly higher than their counterparts,also was increased in Dukes C,D stage than DukesA, B stagep

MMP-1对大肠癌的浸润转移有促进作用，MMP-1高表达者提示预后不良；MMP-1与大肠癌的肿瘤血管生成有正相关性，两者可能存在某些内在联系，MMP-1可能是促进大肠癌血管生成的因素之一。

PAB, isolated from the traditional Chinese medical plant Pseudolarix kaempferi Gorden , was found to be an early pregnancy-terminating agent in 1980s.

在国家973项目的支持下，我们展开了一系列新生血管生成抑制剂的筛选和研究，并得到了几个具有较强抗新生血管生成作用的先导化合物。

HAase may degrade antiangiogenic HA of extracellular matrix, which may stim ulate proliferation of endothelial cells and enhance the curative effect of grow th factors to myocardial ischemia.

HAase可降解细胞外基质中具有抗血管新生作用的HA，促进内皮细胞的增殖，有可能提高促血管生长因子治疗心肌缺血的局部疗效。

Carvedilol, a non-cardioselective vasodilating BB is more effective in reducing portal pressure than propranolol, but to date there have been no clinical studies assessing the efficacy of carvedilol in primary prophylaxis.

与心得安相比，卡维地洛，这种非心脏选择性扩张血管的BB，能更有效的降低血管入口处的压力，但至今尚没有临床研究对卡维地洛的主要预防作用进行评估。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。