血管作用的

Endothelin-1(ET-1)is the most strong and lasting perfuse vaso-excitor material which known at present.

内皮素-1(endothelin-1， ET-1)是目前已知的作用最强和最持久的缩血管物质，对局部血流灌注调控具有重要作用。

Also found in the circulation, the des-ASPheptapeptide is as active as angiotensin II instimulating aldosterone release but has much less pressor activity.

同样可以在血循环中发现的去天门冬氨酸七肽，它在刺激醛固酮释放时的作用与血管紧张素Ⅱ一样，但其升压作用则不如后者。

NO could be synthezied for maintaining the resting cerebrovascular tonus in normoal condition and was involved in the vasodilatation mechanism under hypoxia. In these 2 aspects, the NO effects could be inhibited by L-NNA.

在静息状态时，NO有维持离体基底动脉血管条基态张力的作用；低氧时，NO在脑血管的舒张反应中也占有重要地位，两种作用都可以被L-NNA抑制。

Maximum tolerable dose and lowdose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells ［J］.

在肿瘤的新生血管形成过程中，内皮细胞起决定性的作用，这些内皮细胞一部分直接来自肿瘤组织内原有血管的内皮细胞的芽生生长，一部分来自于骨髓内的内皮祖细胞的动员和释放［2］。

The myodynamia had, to some extent, improved without nursing complications found. Conclusion: The DSA could promote the recall rate of ICVD, which is a necessary standard for evaluating the narrow of cerebral artery and cerebral arterial occlusion and also is necessary for the choice of treatment plan. It is very important for the further treatment of ICVD and the sound nursing care is one of the successful factors for DSA.

数字减影血管造影能够提高缺血性脑血管病的检出率，是评价脑血管狭窄、闭塞和选择治疗方案的金标准，它对缺血性脑血管病的进一步治疗起着关键性的作用，良好的护理配合是数字减影血管造影成功的因素之一。

The biological characteristics of the CCM are mainly relevant to the unmaturity of the vessel wall. A series of angiogenic factors play an important role in the development of the lesion. The proliferative activity of the CCM needs to be studied further. The different clinical presentations of CCM was based on its pathological diversity.

CCM生物学特性主要与其血管壁组织结构的不成熟有关，各种血管因子发挥了相当重要的促进作用，CCM本身的增殖活性有待进一步研究；CCM不同的临床表现与其病理特点的差异密切相关。

Angiogenesis is regulated by signals derived from receptors for both growth factors and ECM molecules. Recent studies have shown that activation of ERKs is closely involved in the migration or tubular-like formation of endothelial cells and induced by various angiogenic factors.

血管新生可以受到许多来自於生长因子受器及胞外基质受器的讯息所调控，而近年的研究也显示ERK的活化不但会受到许多促血管新生因子的诱导，而且跟内皮细胞的移型及管状形成作用有很大的关系。

objective:to investigate the expression and significance of rb in the occurrence, development and regression of infantile hemangiomas.methods:the expression of rb was examined in the proliferative stage and catagen of human hemangiomas and normal skin tissues by using immunohistochemical technique.immunohistochemical technique for factorⅷ-related antigen was used to prove that the cells which expressed rb were endothelium.image analysis system was applied to measure the expression level of rb at different stages of hemangiomas and in normal skin tissues.results:the expression of rb was significantly lower in proliferating hemangiomas than that in involuting hemangomas(p.05).conclusion:rb might play an important role in the regression of human hemangioma endothelial cells and anti-angiogenesis.

目的：探讨rb蛋白在血管瘤发生、发展及退化过程中的表达状况及其意义。方法：采用免疫组织化学方法检测人皮肤血管瘤增生期、退化期及正常皮肤组织中rb的表达水平，并结合第ⅷ因子相关抗原的免疫组织化学染色证实表达rb的细胞是血管内皮细胞。利用计算机图像分析技术测量不同时期血管瘤组织和正常皮肤组织rb表达的积分光密度和面积。结果：增生期血管瘤内皮细胞rb表达水平低于退化期，差异有显著性（p.05），退化期血管瘤内皮细胞rb表达水平与正常皮肤组织相比，差异有显著性（p.05）。结论：rb通过抑制血管瘤内皮细胞增殖和血管生成而在血管瘤的退化过程中起重要作用。

objective to observe the protective effect of qiliqiangxin capsule in rabbit heart ventricle reconstitution of chronic heart failure.methods using the method of giving rabbit abdomen aorta half ligations to build the chronic heart failure model to observe qiliqiangxin capsule the effect to blood flow mechanics index,room wall thickness,heart exponent and heart ventricle reconstitution biochemistry index.results qiliqiangxin capsule could reduce effectively bp,lvsp,lvedp,t wave,improve room wall thickness and heart exponent,reduce angii and alt,all the paramenters ahd notable difference,composed to those of model group (p＜0.05,p＜0.01).conclusion qiliqiangxin capsule can improve the blood flow mechanics change of chronic heart failure rabbit,which has notable inhibitory action on heart ventricle reconstitution which originate from chronic heart failure.inhibition of ang ii,alt of immune nerve endocrine system may be a mechanism of qiliqiangxin capsule.

观察血流动力学、标志心室重构的室壁厚度及心脏指数及肾素―血管紧张素―醛固酮系统相关生化指标的变化。结果芪苈强心胶囊可有效降低血压、左室压、左室末期舒张压、t波，改善室壁厚度和心脏指数，降低血清血管紧张素ii及醛固酮水平，与模型组比较均有显著性差异(p＜0.05，p＜0.01)。结论芪苈强心胶囊可改善慢性心力衰竭兔血流动力学的变化，对慢性心力衰竭引起的心室重构具有显著抑制作用，其机制可能与该药发挥抑制神经内分泌免疫系统rass中angii、ald的水平有关。

The gaseous monoxides nitric oxide and carbon monoxide, generated within the blood vessel wall, have been identified as important cellular messengers involved in the regulation of intracellular cGMP levels, platelet aggregation and smooth muscle relaxation, The mechanism by which carbon monoxide activates soluble guanylyl cyclase is similar to that of nitric oxide, and involves binding and dislocation of its heme-iron to induce a conformational change and activation of the catalytic site of guanylyl cyclase.

一氧化氮是体内最重要的气体信使分子，不仅是维持血管正常舒缩功能的重要介质，而且还有抑制单核细胞及血小板与内皮的粘附、聚集、抑制血管平滑肌细胞的增殖等作用。近年研究表明，内源性一氧化碳是体内另一个重要的气体信使分子，它是由血红素氧合酶氧化分解血红素产生的，具有与一氧化氮相似的生理功能。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐