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Background and objective It has been known that vasoactive intestinal peptide has the effect of promoting the growth of some malignant tumors, but its mechanism is not clear.

背景与目的血管活性肠肽对多种肿瘤细胞的生长具有促进作用,但其作用机制尚有许多未解之处。

The NO content and the NOS activity were down in the PIH pregnant women placenta.This showed that the ghrelin regulated the VEGF and influenced the the NO down.And the placenta angiospasm,blood pressure highten, and the PIH were caused also by this. The ghrelin,VEGF,Flt-1,NO and NOS were detected by the SP-immunochemistry, RQ-PCR,cell culture in vitro,ASODN and nitrate reductase in the normal pregnancy,PIH placenta and the cultured HUVEC antisense blocking ghrelin in vitro.

结果证实:PIH孕妇胎盘组织中Ghrelin,VEGF、Flt-1蛋白和mRNA水平下降与正常孕妇比较有显著性差异p<0.05提示在PIH发病过程中Ghrelin可能对VEGF,Flt-1蛋白和mRNA的表达具有下调作用,进而影响胎盘血管网的形成和发育;NO含量与NOS活力水平在PIH孕妇胎盘组织中下降,提示Ghrelin可能通过下调VEGF的表达进一步影响血管舒张因子NO水平下降,进而引起胎盘血管痉挛,血压升高,最终导致PIH的发生。

Aim To observe the effects of Chlamydia pneumoniae infection on migration of endothelial cells, to investigate the interventive effect of Berberine on Chlamydia pneumoniae induced-endothelial cell migration and to explore its possible mechanism.

目的 观察肺炎衣原体感染对人血管内皮细胞迁移的影响,探讨黄连素对其干预作用及作用机制。

Objectives In order to investigate how does King's Brain pill work or mechanism of King's Brain pill effective in treating AD clinically, we observed effects of extract of King's Brain on neuronal and vascular lesions induced by Aβ combining with praxiology and neuropathology.

目的 运用现代分子神经病理学和行为学技术,围绕炎症假说、淀粉样蛋白瀑布流假说,以神经元和脑血管为保护目标,着眼于AD的关键病理机制Aβ(β淀粉样蛋白沉积和淀粉样血管病变)及其代谢,开展中药补肾活血化痰复方制剂金思维对损伤的神经元和血管的保护作用机理研究,从而探讨其防治老年性痴呆的机理。

The above-mentioned results illustrate: the mechanism of pseudobulbar palsy treated with nape needle was possible about brain plasticity after stroke, for example, it could relieve spasm of muscle, recovery muscle strength, facilitate pharyngeal muscle to move coordinated; formate long term protention with uninterrupt mechamism stimulations , reconstructe damaged reflex arch ; accelerate blood circulation, ameliorate ischemia and anoxia; influence metabolism of angeogenesis growth factors, improve angiogenesis and protect neurons.

项针治疗脑卒中后假性延髓麻痹的疗效肯定,其机理可能主要与缓解肌肉痉挛,恢复肌力,促进咽部肌肉的协调运动;对病变部位长期不断的机械刺激,形成长期强化作用,使受损反射弧得以重建;促进血液循环,改善病变局部缺血缺氧状态;影响血管生成生长因子的代谢,促进血管生成,保护神经元等,脑卒中后脑可塑性改变有关。

Shed blood reinfusion alone did not restore the decreased vascular reactivity. ICI174,864 improved the decreased vascular reactivity in dose-dependent manner.

单纯回输失血不能纠正血管的低反应性,ICI174,864对休克血管的低反应性有不同程度的恢复作用,且呈一定的剂量依赖关系。

The arise of Ang II was found in thecal cells specially, the reason could be due to an abundance of blood vessels in the thecal cell layer, but not in the granulosa layer. E2, P, T may play very important roles in the follicle development and atresia.

RAS的变化主要发生在卵泡膜细胞,可能与卵泡膜细胞层具有丰富的血管而颗粒细胞层中无血管有关。E2、P、T具有不同程度的促进卵泡发育和抑制闭锁的作用。

The expression of p-p38 and Rho GDIαwas upregulated in LCA by either low shear stress or hypertension. However, the highest expression of p-p38 and Rho GDIαwas observed in LCA of low shear stress accompanied by hypertension.(4) Effect of low shear stress on both decreasing apoptosis and increasing proliferation of VSMCs in LCA was reversed by tributyrin, a HDAC inhibitor.

当高血压伴有低切应力时,两者的协同作用诱导p-Akt的表达水平进一步增加;(3)高血压和低切应力都可以诱导颈总动脉p38和Rho GDIα表达增加;当高血压伴有低切应力时,两者的协同作用诱导颈总动脉p38和Rho GDIα表达进一步增加;(4)HDAC抑制剂Tributyrin可以通过抑制VSMCs增殖,促进VSMCs凋亡,在干预低切应力诱导的血管重建中发挥作用。

Conclusion] Octreotide has inhibition to the growth of rat HCC .This effect may be completed by inhibiting vasculogenesis.

结论] 生长抑素对大鼠肝癌的生长具有抑制作用,这种抑制作用可能通过抑制血管生成完成。

Excessive neural input does not mediate diminished vasoconstrictive responses in the ACL transected knee; inflammatory mediators may play a role in the deficient vascular responsiveness of the ACL transected knee.

过量的神经输入没有能够调节前交叉韧带切除了的膝关节的血管收缩应答反应;炎症调节因子可能在前交叉韧带切除的膝关节血管应答不良中期重要作用。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。