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Result: The series of Muskone decreased arterial blood pressure significantly, dilated coronary artery and peripheral arteries significantly, increased coronary blood flow, decreased resistance in coronary artery, improved the work of left artrium, the oxygen availability of cardiac muscles and the complaisance of arteries in cardiac muscles.

结果:冠心苏合丸系列组方可明显降低动脉血压,扩张冠脉血管及外周血管,增加冠脉流量,降低冠脉阻力;改善左室做功和心肌氧利用率,调整心脏血管的顺应性。结论:对心血管系统起到调整和改善作用。

The mechanism probably is that Pishang can inhibit the growth, movement and adheresion to extracellular matrix and endothelial cell of liver tumor cells, up-regulate the expression of nm23, down-regulate the expression of CD44, MMP-2, and inhibit the tumor neovascular by supressing the vascular endothelial cell, down-regulating the expression of VEGF, damaging the primitive mesenchymal cells and inhibiting neovascular gemmation.

砒霜具有明显的抗肝癌细胞作用,并有一定的抗侵袭与转移作用,其机制可能与其能抑制肝癌细胞增殖、迁移、阻止肝癌细胞与细胞外基质和内皮细胞粘附、上调肿瘤转移抑制基因nm23表达、下调肿瘤侵袭分子CD44、MMP-2表达以及通过抑制内皮细胞增殖、下调VEGF表达、损伤间充质细胞、阻止新生血管芽生等途径从而抑制肿瘤新生血管形成有关。

Although a single intracardial injection of an adenovirus containing the AT2R into male Sprague-Dawley rats did not affect the MAP, the effectiveness of an AT1R antagonist was greater in the AT2R-overexpressing animals compared with those expressing a control vector.7

虽然在雄性斯普拉-道来大鼠心内注射包含血管紧张素II受体血管紧张素II受体的腺病毒后没有观察到平均动脉压的上升,但是在血管紧张素II受体过度表达的个体血管紧张素I受体拮抗剂在血压调控中起到了更为有效的作用。

RESULTS MMF and DEX were found to inhibit angiogenesis of HUVEC in vitro, and this effect was more potent in MMF.

结果:霉酚酸酯对血管内皮细胞体外血管发生有着较强的抑制作用,而地塞米松的抑制作用相对较弱。

Although angiogenic roles of hypoxia-inducible factors are well known, the roles of PHDs in the ascular system remain to be established.

HIF在血管生成中的作用已经明确,但是PHDs在血管系统中的作用尚无报道。

Objective: To asterin whether the tutor's experience prescription-Cooling vessel 791-2 granulae prescription can promote collateral vessel generatation and stimulate angiogenesis in severe hind limb ischemia animal model, in order to get a clear unstanding of the curative effect mechanism, so that providing theory foundation for clinical using.

目的:探讨导师经验方清脉791-2冲剂对肢体缺血动物模型的促血管生成作用及其疗效机理,为临床应用提供理论基础。目的:探讨导师经验方清脉791-2冲剂对肢体缺血动物模型的促血管生成作用及其疗效机理,为临床应用提供理论基础。

Under the direct current electric field, the expression of PDGFR were increased obviously and distributed asymmetricly on the membrane of VSMC. This receptor were mainly focused on the cathodal side of cellular membrane in electric field. The AT1R were also enhanced in the cells after exposure to the electric field, and the expression of AT2R had showed the changeless.

改进的电场干预装置作用下,血管平滑肌细胞膜血小板源生长因子受体表达增加,部分细胞内血小板源生长因子受体表达上调,呈不对称分布,在电场负极面较集中;细胞中血管紧张素Ⅱ1型受体表达亦增加,但无明显不对称分布现象;血管紧张素Ⅱ2型受体表达改变不显著。

As a new messenger factor,carbon monoxide can activate soluble guanyl cyclas,relax angio-smooth muscle,prevent platelet from aggregation and inhibit angio-smooth muscle cells proliferation,therefore it can maintain normal blood stream in coronary artery.

一氧化碳是一种新的信使因子,通过激活可溶性鸟苷酸环化酶,舒张血管平滑肌,抑制血小板聚集和抑制血管平滑肌细胞增殖,从而恢复冠状动脉的正常血流。血红素氧合酶通过其抗动脉粥样硬化作用对冠状动脉起保护作用。

These include physical characteristics, such as repulsive forces resulting from the electronegative charge of both platelet and endothelial cell membranes, and biochemical attributes, such as the synthesis and release of inhibitors of platelet activation. Platelets respond rapidly to alterations of endothelial cells and to exposure of subendothelial structures by attaching firmly to the site of the lesion.

正常情况下,循环中的血小板与血管壁内皮细胞层紧密接触但不发生黏附,是因为血管内皮细胞具有一定的活性功能,包括一些物理特性如血小板和内皮细胞膜均带有负电荷产生相互排斥作用以及生化作用如合成和释放血小板活化抑制剂。

As a biomarker of vascular endothelial cells proliferation,CD105 stimulates vasculogenesis and plays key role in tumor angiogenesis.

CD105是血管内皮细胞增殖的标志之一,同时直接参与血管生成,在肿瘤血管生成过程中发挥重要作用。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。