血管作用的

Changes in blood flow are secondary to a relaxation of small arteries and arterioles, whilst changes in microvascular permeability, leading to inflammatory edema formation and cell accumulation, are mediated via changes that occur at the postcapillary venule level.

血管活性肽分子及其相关肽段可以内分泌的方式发挥循环激素的作用，还可以旁、自分泌的方式，通过其靶细胞表面的G蛋白偶联受体，在血管局部发挥其调节血管舒缩、细胞增殖迁移和分泌等复杂的生物学作用。

According to the above results, we discuss the effective mechanism of Wenxin capsule anti- atherosclerosis atherosis in detail which is protecting vessel endolethial cell, regulating angiotasis, anti-platleo aggregation and inhibiting proliferation of smooth muscle cell.

依据上述结果对温心胶囊抗动脉粥样硬化作用机理进行了详细论述，认为其作用主要是通过保护血管内皮细胞、调节血管张力、抗血小板聚集及抑制平滑肌细胞增殖而实现的。

The pressor effect of adenosine was due to carotid body cheoreceptor activation. However, a slight increase of ABP induced by intracarotid bolus injection of adenosine following the section of carotid sinus nerves was observed in a few rats, which implied that the central effect might be involved in the pressor effect of adenosine. The delayed effect of adenosine may be attributed to the direct actions (including the negative chronotropic action, thenegative dromotropic action, the negative inotropic action and the vasodilator effect) of adenosine on the heart and blood vessels.

前一效应主要与颈动脉体化学感受器的激活有关，但在少数动物，颈动脉内注射腺苷的升压效应在切除窦神经后并未完全消除，表明腺苷有可能进入神经中枢而发挥作用；后一效应可能由腺苷直接作用于心脏和血管，通过其负性变力、变时、变传导和血管扩张等作用，导致心脏自律性降低，输出量减少和外周阻力下降。

To pay attention to carry out effective cardiopulmonary resuscitation, hemostasis by compression and deep vein intubation rapidly in the initial stage of emergency. The carotid shunt tube plays an important role in severe carotid injury and re-establishment process. We use external jugular vein to transplant and re-establish,which are rung with artificial blood vessels for the long distance carotid injury and achieved the best result. We expose as fully as possible for the hepatic venae and the posthepatic post caval injury,and adopt effective methods to stop bleeding and repair. The application of blood shunt pump could raise the success rate for those severe patients. The self-double vastransplantation with both ends being all trousers-style one opening solve some problems such as there are no suitable caliber self-transplantation blood vessels and the artificial blood vessels are easy to occur obliteration for long-term and so on for the great or middle blood vessels.We use improved Fogarty duct and anterograde intubation to eliminate thrombus could eliminate thrombus effectively and avoid accessory injury for the deep vein injury and extensive thrombosis.

抢救初期要注意进行有效的心肺复苏、压迫止血和快速进行深静脉插管；颈动脉转流管在严重颈动脉损伤重建过程中有重要作用；对长距离颈动脉损伤用颈外静脉移植外环包人造血管重建，可取得最佳效果；对肝静脉及肝后下腔静脉损伤，要充分暴露，采用有效方法止血和修复，对病情极危重的凶险性出血者，血液转流泵的应用可提高成功率；对大、中血管损伤，两端均为裤式单开口自体双血管移植，解决了无适宜口径自体移植血管和应用人造血管远期易闭塞等问题；对深静脉损伤并广泛血栓形成者，应用改进的Fogarty导管和顺行插管取栓法，可有效取栓并避免了副损伤。

To pay attention to carry out effective cardiopulmonary resus-citation,hemostasis by compression and deep vein intubation rapidly in the initial stage of emergency.The carotid shunt tube plays an important role in severe carotid injury and re-establishment process.We use external jugular vein to transplant and re-establish,which are rungwith artificial blood vessels for the long distance carotid injury and achieved the best result.We expose as fully as possible for the hepatic venae and the posthepatic post caval injury,and adopt effective methods to stop bleeding and repair.The application of blood shunt pump could raise the success rate for those severe patients.The self-double vastransplantation with both ends being all trousers-style one opening solve some problems such as there are no suitable caliber self-transplantation blood vessels and the artificial blood vessels are easy to occur obliteration for long-term and so on for the great or middle blood vessels.We use improved Fogarty duct and anterograde intubation to eliminate thrombus could eliminate thrombus effectively and avoid accessory injury for the deep vein injury and extensive thrombosis.

抢救初期要注意进行有效的心肺复苏、压迫止血和快速进行深静脉插管；颈动脉转流管在严重颈动脉损伤重建过程中有重要作用；对长距离颈动脉损伤用颈外静脉移植外环包人造血管重建，可取得最佳效果；对肝静脉及肝后下腔静脉损伤，要充分暴露，采用有效方法止血和修复，对病情极危重的凶险性出血者，血液转流泵的应用可提高成功率；对大、中血管损伤，两端均为裤式单开口自体双血管移植，解决了无适宜口径自体移植血管和应用人造血管远期易闭塞等问题；对深静脉损伤并广泛血栓形成者，应用改进的Fogarty导管和顺行插管取栓法，可有效取栓并避免了副损伤。

Supplementation of folate in diets may reduce hyperhomocysteinemia induced by excess intake of methionine and decrease the expression of NF-κBP65 protein and monocyte chemoattractant protein-1 (MCP-1) in carotid common artery after balloon angioplasty, These data show that Hcy may exacerbate neointima hyperplasia after denuding injury by increasing the expression of inflammatory factors via the activation of NF-kB, Folate can reverse the effect of Hcy on the activation of NF-κB and the expression of MCP-1, an effect of preventing the restenosis postangioplasty.

而Hcy有可能通过激活核转录因子通路增加损伤血管组织炎症因子的表达而加重血管球能损伤后新内膜的过度增生过程，叶酸能对抗Hcy的上述作用，对高同型半胱氨酸血症引起的血管成形术后再狭窄可能有一定的预防作用。

Vascular endothelial growth factoris a new kind of blood vessel active factors was finded in recent years. It not only plays a very important role in the process of micrangium proliferation but also contributs to the stabilizing, maturating and refraining from apoptosis of nascent micrangium, it participates the vascular endothelial cell through specific binding with corresponding receptor.

血管内皮生长因子(vascular endothelial growth factor， VEGF)是近年来新发现的血管活性因子，通过与相应受体结合特异性的作用于血管内皮细胞，不仅在毛细血管增生中起着十分重要的作用，而且对于稳定新生的毛细血管，使之成熟，避免凋亡具有重要意义。

The positive expression rates of Tissue Inhibitors of Metalloproteinase-2 protein in the cases of involuting groups were significantly higher than those in proliferating group and vascular malformation groups and normal skin group (P.05). Its difference was significant. Conclusions: Matrix MetallProtinase-2 and Tissue Inhibitors of Metalloproteinase-2 may play an important role in the pathogenesis of hemangiomas through angiogenesis. They may have no effect on vascular malformation and normal skin

血管瘤退化期，TIMP-2表达明显升高，说明 TIMP-2与血管瘤纤维化、消退有关，其机制可能是一方面通过抑制MMP-2介导的基底膜降解而在内皮细胞迁移、聚集中起作用，另一方面直接抑制内皮细胞的增殖及迁移，使内皮细胞高频率调亡，细胞外基质增多，组织出现纤维化，最终导致血管瘤的退化。2、血管畸形和正常皮肤小血管中MMP-2和TIMP-2不表达或表达较弱，说明血管畸形和正常皮肤小血管中并不存在异常的血管生成，据此可以对血管性疾病进行分型、分期，并指导临床治疗。

Screened with cOnidia of hauIthe mp, the bo of myce1iageednated frOm cOnidia of Prtubo mp was Observd Whe the mixtUr of CS-l l andcs-l2, aS well aS the COmPoUnd cs-7 were Presot. And the mtw of Cs-1l and cs-12shOwed grOWth-inhibitory activity ofendothlial cells and NIH-3T3 fibrobast in the.

稻瘟霉活性筛选结果显示CS-11和CS-12的混合物、CS-7具有使稻瘟霉孢子菌丝体变形的作用；体外药理实验显示，CS-11和CS-12的混合物具有显著的体外抑制血管内皮细胞生长作用及抑制血管成纤维细胞生长作用。

Vascular endothelial cell growth factoris a kind of glucoprotein ,which has separated by culturing stellate cells of bovine glandula pituitaria in vitro by Ferrara etc. in 1989.lt can express that anxo-act vascular endothelial cell growth specificly and induce vasotropic growth ,so it is called VEGF.

血管内皮细胞生长因子(Vascular endothelial cell growth factor)是1989年Ferrara等牛垂体星状细胞体外培养分离出的一种糖蛋白，其在体内外都表现出特异性地促进血管内皮细胞的生长并诱导血管生成作用，故此称为血管内皮细胞生长因子。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。