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The mice inoculated with Coxiella burnetii intrana- sally developed interstitial pneumonia,while the primary pathological changes of mice inoculated intraperitoneally are granulomas in spleen and liver.2.The pathological changes became more severe followed the dosage increasing.3.Coxiella burnetii can be detected in spleen and liver at day 2 after inoculation.the lesion became more and more serious from day 2 to day 12.The characteristic changes were observed at day 7,and recovered at day 14. 4.The reticuloendothelial system are main target of Coxiella burnetii.The pathogen was detected in cytoplasm of monocyte -macrophages of spleen, liver, lung, and endothelioid cells of blood vessel. 5. Coxiella burnetii can be found in macrophages lysosomes by electron microscopy. Most of them are round or rod, and polymorphic shape can also be observed in different size.

结果:1、通过不同感染途径的实验证实,滴鼻感染的小鼠主要表现为间质性肺炎,而腹腔注射感染小鼠则以脾脏、肝脏肉芽肿为主要病变。2、通过不同剂量的感染实验发现,随着感染Q热立克次体剂量的加大,动物病变愈加严重。3、通过感染后不同时间的动态病理学观察发现,在腹腔注射后第2d的脾和肝脏即可发现病原体,主要脏器的病理变化从第2d到第12d逐渐加重,第7d动物的病变最典型,至感染后14d动物的受损器官已开始出现修复性变化。4、 Q热立克次体主要侵害机体的网状内皮系统,在感染小鼠的肝、脾、肺和外周血管单核巨噬细胞以及血管内皮细胞胞浆中查见病原体。5、透射电镜观察可见Q热立克次体主要位于巨噬细胞吞噬溶酶体内,呈多形性,多见圆形和杆状,大小不一。

Methods One case of epithelioid hemangioendotheloma was observed on hi-stopathologic characteristics and immunohistochemical staining with review of the literatures.

观察和分析1例子宫上皮样血管内皮瘤的病理形态特征和免疫组化标记并结合文献复习总结子宫上皮样血管内皮瘤的临床病理学特点和鉴别诊断。

Methods One case of epithelioid hemangioendotheloma was observed on hi-stopathologic characteristics and immunohistochemical staining with review of the literatures.

观察和分析1例子宫上皮样血管内皮瘤病理形态特征和免疫组化标记,并结合文献复习,总结子宫上皮样血管内皮瘤临床病理学特点和鉴别诊断。

Furthermore, the index-evaluated angiogenesis has a significant correlation with microvascular density. So contrast-enhanced ultrasound can help predict prognosis and select treatment plan of anti-angiogenic therapy and exairesis et al.

同时其反映肿瘤血管的指标与肿瘤微血管密度具有较高的相关性,从而为预测预后及抗肿瘤血管生成的疗法、手术切除等治疗方案的选择提供重要的依据。

Meanwhile the lung tissue slide was prepared for electron microscopic observation at 180 minutes after reperfusion.Result: HO-1 expression was upregulated in two groups in the pulmonary endothelial cells,part of pulmonary vascular smooth muscle cells,extima of vessels and epithelial cells of airway,the absorbance was 0.148±0.013,0.158±0.012,respectively.The Shenmai injection group showed higher absorbance than those of the IRI group( P .01),lower W/D and IAR values than those of the IRI group( P .01) significantly and lighter abnormal changes of the lung tissue in morphologically than those of the PIRI group.

结果:HO-1在I-R组、SM组肺血管内皮、部分血管平滑肌、外膜层及部分气道上皮均有阳性表达,原位杂交的平均吸光度分别为0.148±0.013,0.158±0.012,SM组HO-1的表达水平明显高于I-R组( P 。01),W/D,IAR值显著低于I-R组( P 。01),肺组织形态学异常改变轻于I-R组。

The extracerebral CCM group,completely different from the intracerebral one, presented elastic and thick-wall vessel.

脑外组CCM表现为弹性较好的厚壁血管,脑内组为弹性较差的薄壁血管

Objective To explore the incidence of extrarenal vascular complications of hypertension in aged patients with micro-albuminuria and to investigate the relationship between the urinary albumin excretion rate and the endothelial dysfunction.

目的 观察老年高血压患者伴微量白蛋白尿时肾外血管病变的情况,并探讨尿白蛋白排泄率与血管内皮功能障碍之间的关系。

To explore the incidence of extrarenal vascular complications of hypertension in aged patients with microalbuminuria and to investigate the relationship between the urinary albumin excretion rate and the endothelial dysfunction.

目的 观察老年高血压患者伴微量白蛋白尿时肾外血管病变的情况,并探讨尿白蛋白排泄率与血管内皮功能障碍之间的关系。

When AT1 receptors are eliminated from the kidney, the residual repertoire of systemic, extrarenal AT1 receptors is not sufficient to induce hypertension or cardiac hypertrophy.

当从肾脏中去除血管紧张素Ⅰ受体,肾外的周身其余部分的血管紧张素Ⅰ受体不足以导致高血压及心脏肥厚。

It had advantages regarding demonstration of extravascular lesions.

结果 23例患者的3d dce mra显示血管清晰,达到诊断要求,并且具有能同时显示血管外病灶的特点。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。