血管

There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.

人及哺乳动物体内有四种结构及药理学性质略有差异的异物体，分别为ET-1、ET-2、ET-3、ET-β，而在人主要是ET-1，在生理条件下，ET-1在血浆中含量较低，约为5ng〓，故ET-1不是一个循环激素，而是局部合成释放，局部起作用的活性物质，半衰期约1小时，ET-1是目前已知的最强的血管收缩剂，对静脉的作用比动脉强，在血管床，ET受体有A、B两型，A型主要分布在平滑肌细胞，B型主要分布在内皮细胞，它可以通过旁分泌途径刺激内膜增生，具有有丝分裂原效应，可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩，使静止期SMC进入增殖期，还可以通过信号传导途径，与bFGF、GTF-β、PDGF等生长因子协同作用，起共有丝分裂原作用。

The novel suture or occlusion device for puncture site used in clinic, such as Angio-Seal or Perclose, significantly reduces bed lying and hospital stay of the patients, and attenuates peripheral vascular damages.

而近年来临床上应用的一些新型的针对穿刺点局部的缝合或封堵装置，如：Angio-Seal血管封堵器，Perclose血管缝合器等，不仅可以明显减少患者的卧床时间和住院时间，也可以减少对外周血管的损伤。

The expression of the pulse wave characteristics is based on the physiological nature of the arterial wall,the arterial blood and the perivascular tissue from the physical and mathematical points.

从动脉血管系统的血管壁、血液以及动脉血管周围组织的生理物性出发，建立了脉搏波波形特征的数学表达式，从物理学以及数学的角度在理论上分析了脉搏波波形的特征随生理参数的变化情况。

Evidence of systemic vasculitis was found in a muscle biopsy of the rectus femoris in 9/14 (64%) patients with vasculitis with neuropathy and in 3/11 (27%) patients with purpura/petechiae and vasculitis of the skin.

有神经疾病和紫癜/紫斑及皮肤血管炎患者的类风湿血管炎患者进行股直肌肌活检，分别发现60%（9/14）和27%（3/11）有系统性血管炎证据。

Therefore, it is important for study molecular mechanism of VSMC phenotypic regulation.

由VSMC表型转化所引发的血管重构是血管再狭窄和动脉粥样硬化等血管病变发生发展的根本原因。

Special staining methods, such as Masson and the Van Gieson staining were used to study the distribution of collogen fibers and elastic fibers. ResultsBy HE staining, the subepithelial connective tissues and vessels in the pterygium were more prominent than normal conjunctival tissues. An amorphous subepithelial superficial hyalinized zone and coarse eosinophilic granular materials were observed in the pterygia, but they were not found in normal conjunctival specimens. Coarse fibers were visible only in the deeper subepithelial connective tissues of pterygial samples. With Masson′s staining, the dense staining of collagen fibers was also more prominent in the pterygium than in the subepithelial connective tissues of normal conjunctiva. Abnormal collagen fibers were visible in the deeper sub-epithelial connective tissues of pterygial samples. With Van Gieson staining, abnormal collagen fibers were visible in the deeper subepithelial connective tissues. Dark coarse elastic fibers were found in the abnormal fibers only in the subepithelial deep connective tissues of pinguecula in the pterygia but not in the conjunctiva. With immunohistochemistry staining, MMP-3 was strong in the pterygial epithelium, moderate in fibroblast and absent from pterygial vascular walls. LN was strongly expressed in the blood vessel wall, moderately in the epithelial basement membrane and absent from the entire stroma.

结果HE染色：翼状胬肉组织上皮下基质中存在结缔组织的增生和血管形成；基质浅层存在一无定形物质透明区及粗糙的颗粒样嗜酸性物质，在翼状胬肉体部深层基质中存在粗糙的纤维组织；正常球结膜组织细胞排列整齐；基质为疏松结缔组织，胶原纤维平行排列，其间可见成纤维细胞，散在少量中性粒细胞、毛细血管；Masson染色：翼状胬肉浅层基质中存在致密的胶原纤维染色，深层基质中的胶原纤维存在变性样改变；VG染色：翼状胬肉组织深层基质中存在大量变性的胶原纤维，其间夹杂黑色的弹性纤维；免疫组化染色法：MMP-3在翼状胬肉上皮细胞中呈强表达，成纤维细胞中呈中等强度表达，血管内皮细胞中未见表达；LN在血管壁中呈强表达，在上皮细胞基底膜中呈中等强度表达，在整个基质中未见明显表达；col Ⅲ在整个翼状胬肉基质中呈强表达。

Fluorescein and indocyanine green fundus angiography were used to evalute the macular morphologic results. Results The result of fundus angiography showed that 90 cases 98 eyes had choroidal neovacularization, There were exudation age-related macular degeneration 39 cases (44 eyes), idophaic CNV 23 cases (23 eyes) and highly myopia 22 cases (25 eyes), Polypoidal Choroidal Vasculpathy 4cases (4eyes), multifocal choroidit 1 case (1 eye )and nodifferentiate 1 cases.

结果 90例98只眼黄斑部出血患者的眼底血管造影结果显示有脉络膜新生血管，其中老年黄斑变性湿性型39例44只眼，中心性渗出性脉络膜视网膜病变23例23只眼，高度近视22例25只眼，息肉状脉络膜血管病变4例4只眼，多灶性脉络膜炎1例1只眼，诊断不明1例。

When contrast-enhanced CT depicts hyperascularity of the mesentery with ascular dilatation, tortuosity, and wide spacing of the asa recta, the comb sign is produced.

当增强CT显示血管扩张、迂曲而血管增多的肠系膜和广泛分布的直小血管，产生梳征。

This plaque will cause an obstruction that interferes with the man''''s ability to get an rection.

由于血管壁上形成血栓，高血压导致通往前列腺的血管血流量减少，血栓会造成血管堵塞，影响男性的勃起能力。

Objective: To discuss the protective effects of Fuwai modifed solution combined with nicoranil on the endothelium-derived hyperpolarizing factor-mediated relazation relaxation of saphena vessel graft.

目的：探讨常温下阜外改良(Fu Wai Modified， FWM)器官保护液＋尼可地尔对大隐静脉血管桥血管内皮超极化因子介导血管舒张功能的影响。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。