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The antifungal activities of these materials were investigated and build foundation to develop low poison plant antifungal products. In experiment, polyphenols were extracted by reflux ectraction method which applyed petroleum ether to degrease and methyl alcohol solvent. Phenolic hydroxyl were examined and inspected by colour-developing reaction and the content of total polyphenols was determined by UV-spectrophotometry. Screening test were performed to the antifungal activities of polyphenol extraction by the tube dilution method to the selected ten pathogenic fungus such as Dothiorella gregaria, Rhizoctonia solani, Phyllosticta pirina, and the minimal inhibitory concentration were measured. The column chromatography and thin layer chromatography were applyed to separate and analyse cortex extracts of Dracaena cochinchinensi Lour.

实验部分采用以石油醚脱脂,甲醇为溶剂的回流提取法来提取植物多酚,用显色反应检识酚羟基;采用紫外分光光度法对多酚粗体物进行总多酚含量的测定;选取了聚生小穴壳菌、立枯丝核菌、梨叶点霉等10株常见农林业致病真菌,采用试管液基稀释法对多酚粗提取物进行了抗真菌活性筛选试验,并测定其最低抑菌浓度;采用柱层析法和薄层层析法对其中抑菌效果较好的龙血竭进行分离分析,根据其中3种化合物的光谱数据UV、IR、~(13C-NMR、1H-NMR和MS鉴定其结构。

Alpha Draconis has not been in alignment for thousands of years.

阿尔法血竭没有在调整了几千年。

AIM: To research protective effect of Sanguis Draconis flavones on cell injury in primary cultured cardiac myocytes.

目的:研究龙血竭总黄酮对乳鼠损伤心肌细胞的保护作用。

Object To investigate the effect of total flavone in Sanguis Draconis on platelet aggregation, thrombus formation and myocardial ischemia in rat and rabbit.

目的:观察血竭总黄酮对大鼠及兔血小板聚集,血栓形成及心肌缺血的影响。

RESULT: Cell survival and release of LDH in culture medium in normal cardiac myocytes were not changed between Sanguis Draconis flavones groups and control group.

结果:60、30、15μgmL^(-1)龙血竭总黄酮对正常生长条件下的心肌细胞活力及LDH浓度无影响。

Cell injury in primary cultured cardiac myocytes could be protected by Sanguis Draconis flavones.

血竭总黄酮对损伤心肌细胞具有一定的保护作用。

Effect of total flavone in Sanguis Draconis on platelet aggregation,thrombus formation and myocardial ischemia

马建建,宋艳,贾敏,李长龄。血竭总黄酮对血小板聚集、血栓形成及心肌缺血的影响。中草药,2002,(11):

ConclusionResina Draconis exerts have a good therapeutic effect on alloxan induced diabetic mice and its mechanism may be related to the increasing of the secretion of insulin and the absorbing of some of the components of Resina Draconis in vivo.

结论龙血竭提取物对糖尿病小鼠有较好的治疗作用,可升高血清胰岛素水平,其部分组分能够被动物体内吸收并进入血液发挥作用。

ResultsResina Draconis had no obvious effects of decreasing the serum glucose level in normal mice, but could decrease the serum glucose level in alloxaninduced diabetic mice.

结果龙血竭提取物对正常小鼠空腹血糖无明显降低作用,能降低四氧嘧啶糖尿病模型小鼠的空腹血糖水平,能改善小鼠对蔗糖的耐受力,增加正常小鼠的胰岛素分泌,血清样本中有药物成分检出。

Also, Resina Draconis improved the sucroseresistance in normal mice and diabetic mice and increased insulin in normal mice. Some of components of Resina Draconis had been measured in serum sample.

结论龙血竭提取物对糖尿病小鼠有较好的治疗作用,可升高血清胰岛素水平,其部分组分能够被动物体内吸收并进入血液发挥作用。

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