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血清疫苗

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Materials and 64 dust acarid allergic rhinitis outpatients were randomly divided into 2 groups, 31 patients in the control group were treated with general immunotherapy, 33 patients in the trial group were treated with NHD, the serum level of IL-4, IL-5 was detected by ELISA.

常年性变应性鼻炎患者64例,随机分为常规免疫治疗组31例,标准化尘满变应原疫苗治疗组33例,比较两组患者在接受免疫治疗后的疗效及血清IL-4、IL-5水平。

At that time, the company was already working jointly with Tokyo's Kitasato Institute, founded by Japanese bacteriologist Shibasaburo Kitasato, the discoverer of antibodies.

国光1960年代开始在台北县树林镇生产血清及动物疫苗,当时就已和日本东京的「北里研究所」进行合作。北里的创办人,就是发现「抗体」的日本细菌学家北里柴三郎。

Objective Isolation of Hantaan-serotype virus strain that could be provided as a better candidate strain for bivalent inactivated vaccine.

目的 从病人血清分离汉坦病毒Ⅰ型毒株,为双价疫苗的配伍提供更好的候选株。

Coli BL21 and purified. The binding activities of immune sera to three EDs were examined with ELISA and Western blotting analysis.②Asthma model was induced with ovalbumin in mice of vaccine group, control vector group and asthma group. Airway pressure-time index and number of cells in BALF were checked. The quantity of goblet cells in bronchiole and the level of MUC5AC mRNA in lung were investigated by PAS staining and RT-PCR assay.

采用ELISA和Western blotting法检测免疫血清抗体对ED的亲合力。2、对DNA疫苗组小鼠制备OVA致敏哮喘模型,检测气道压力峰值—时间指数、支气管/肺泡灌洗液中炎性细胞数量,PAS特染观察小支气管杯状细胞数量及RT-PCR法检测肺组织中粘蛋白MUC5AC mRNA水平,免疫组化和RT-PCR法检测GM-CSF的蛋白与mRNA水平。

This study aimed to compare the effeciveness of ELISA and FAVA in detection of antibody against rabies vaccine.

比较酶联免疫吸附试验与细胞培养病毒中和试验检测狂犬病疫苗免疫后血清抗体。

Results Both GAMP-ADH and GAMP-ADH-Pep10 showed GAMP antigenic specificity. The serum IgG level against GAMP induced by GAMP-ADH-Pep10 conjugate was significantly higher than that by GAMP and showed no significant difference with that by GAMP-ADH-TT vaccine. The conjugate also induced immunological memory.

结果 所制备的多糖衍生物GAMP-ADH及多糖-蛋白结合物GAMP-ADH-Pep10均具有GAMP抗原特异活性,免疫小鼠后可诱生比多糖单独免疫更高水平的GAMP血清IgG抗体,且接近GAMP-ADH-TT疫苗诱生的抗体水平,并能形成免疫记忆。

It is demonstrated CAV 2 adenovirus and named CAV 2 XN 3,after analysing the morphological,physical,chemical and biological features.The authors replicate the virus into hypotoxic and immunize 8 local young canines of two months old,without harmful reactivity being found.

实验将该病毒复制成弱毒疫苗,免疫 8只 2月龄当地幼犬,经临床观察证明,试验犬未出现不良反应;免疫后 14天采血测定血清中和抗体效价达到 1∶12 8,免疫后 2 5天血清中和抗体效价达到 1∶2 5 6 ,免疫后 10个月降至 1∶32 ,但仍能耐受强毒攻击,而对照组 4只犬则发病死亡。

SW-BSA vaccine was used twice to rabbits, the serum antibody titer changes were tested by indirect ELISA assay and attacking toxic with Oxytropis kansuensis (10 g/kg/d) when the antibody titers were in higher level.

SW-BSA疫苗免疫山羊2次,间接ELISA法检测血清抗体效价的变化,抗体效价达到较高后进行甘肃棘豆(10 g/kg/d)攻毒饲喂试验,同时检测血清各项生化指标。

Rabbits were immuned with SW-BSA vaccined twice, the serum antibody titer changes were tested by indirect ELISA assay and attacking toxic with Oxytropis kansuensis (10 g/kg/d) when the antibody titers were in higher. At the same time, the serum biochemical indicators were detected.

SW-BSA白油佐剂疫苗免疫家兔2次,间接ELISA法检测血清抗体效价的变化,抗体效价达到较高后进行甘肃棘豆(10 g/kg/d)攻毒试验,同时检测血清各项生化指标。

These are serologically distinct viruses that are not well protected against by standard serotype 1 vaccine.

这些变异株病毒是血清学差异较大的病毒,使用标准血清1型疫苗不能产生有效的保护。

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