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血浆酶

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MATERIALS AND METHODS: Formaldehyde, an oxidative deamination product of methylamine, was analyzed by HPLC.

材料与方法:利用弱阴离子交换柱层析分离兔血浆蛋白,测定各收集组分的SSAO酶活性;以甲胺为底物测定SSAO酶动力学参数。

The results showed that when the proportion of the resistant subpopulation within the h-VRSA was low, te level of the toxic factor and its pathogenicity to animals had no difference from that of the standard strain. If proportion of the resistant subpopulation increased the level of coagulase and lecithinase changing from positive from negative and the ring of hemolysis disappeared. The speed of proliferation of the organisms in the animal slowed down and the LD50 increased.

结果 当试验菌株中耐药亚群的比例较少时,其毒力因子及动物致病性检测结果与金葡菌标准菌株无显著差异;随着试验菌株中耐药亚群的比例增加,表现为血浆凝固酶、卵磷脂酶由阳性转为阴性,血琼脂平板上溶血环消失,细菌在动物体内增殖速度减慢,对动物的半数致死量(LD50)增加。

OBJECTIVES: Our goal was to evaluate the role of myocardial nicotinamide adenine dinucleotide phosphate oxidase activity and plasma markers of oxidative stress in the pathogenesis of post-operative atrial fibrillation.

摘要翻译:目的:我们的研究目的是评价心肌辅酶Ⅱ(NADPH氧化酶活性和血浆氧化应激标志物在术后房颤发病中的作用。

In order to study the ability to the thrombus formation,41 patients with essential hypertension and 34 patients with normotension were investigated.The plasma level of fibrinogen and tissue-type plasminogen activator antigen and plasminogen activator inhibitor 1(PAI-1)antigen were determined.

为了解高血压病人的血栓形成倾向,我们随机选取了41例高血压病人及34例正常血压者,分别观察了他们的纤维蛋白原及血浆组织型纤溶酶原激活物抗原及纤溶酶原激活物抑制物-1(PAI-1)的含量。

objective to invetigate the variations of plasminogen activator inhibitor-1(pai-1) and tissue-type plsminogen activator in patients with diabetic nephropathy.

目的 探讨2型糖尿病(t2dm)患者血浆纤溶酶原激活物抑制物(pai-1)和组织型纤溶酶原激活物活性水平的变化及其与糖尿病肾病的关系。

Alb, Che and PA were examined by end-point method, enzyme kinetics and immunologic projective turbidimetry method respectively.

血浆清蛋白为终点法、胆碱酯酶为酶动力学法、及前白蛋白免疫投射比浊法。

Wenxin capsule can promote endolethial cells releasing CO and synthesing 〓, enhance activity of HO, induce angiectasis through activating guanylic cyclase and adenglate cyclate of intracellar of vessel smooth muscle cell to enhance content of intracellar cGMP and AMP. 3. Wenxin capsule can inhibit releasing of platelet activiting factor 〓 which inhibit platelet aggregation and have antithrombosis function. 4. Wenxin capsule can promote activity of t-PA, reduce activity of PAI-1, strengthen fibrinolytic function, therefore inhibit fibrin disposition. 5. Wenxin capsule can inhibit synthesis of smooth muscle cellular DNA. Its function don't kill it directly but prevent transformation from period Go to peried S. 6. Wenxin capsule is an effective prescription of anti-coronary atherosclerosis atherosis. The results of image pattern analysis tastifies that area of lipid plaque in treating group reduce 54% and 58% in contrast with that in control group. The results of light, electro- microscopy show that structure of endolethial cell and smooth muscle cell in treating group is more integral than that in control group.

其作用机制之一是由于该药具有良好的调脂降脂作用,其不仅能明显降低血清LDL-c及升高HDL-c含量,且能有效阻止TC沉积于血管壁,从而保护内皮细胞结构完整;此外,温心胶囊尚具有明显的抗氧化作用,该药不仅能明显降低血浆LPO含量,且能提高SOD活性,同时其对血红素在细胞内代谢的调节作用也参与了抗氧化过程。2 温心胶囊能明显促进内皮细胞释放CO及合成〓,提高HO活性,通过激活血管平滑肌细胞内鸟苷酸环化酶及腺苷酸环化酶引起细胞内cGMP、AMP浓度增加而引起血管舒张。3 温心胶囊能明显抑制血小板激活因子〓的释放,从而抑制血小板聚集,抗血栓形成。4 温心胶囊能明显提高t-PA活性,降低PAI-1活性,增强纤溶功能,从而抑制纤维蛋白沉积。5 温心胶囊能明显抑制平滑肌细胞DNA合成,其抑制作用不是直接杀伤抑制,而是阻止细胞由Go期向S期转化。6 温心胶囊是抗冠状动脉粥样硬化的有效制剂,图象分析结果证实,该药治疗组脂斑面积比对照组缩小了54%和58%,光电镜结果显示内皮细胞及平滑肌细胞结构较为完整。

objective to study the changes of t-pa and t-pa inhibitorduring the acute stage of cor pulmonale.methods to measure the plasmatic activity of t-pa and pai by chrom-substrate in60cases of cor pulmonale,compared with the corresponding index of55cases in the control group.results pai was significantly higher in acute stage than in remission stage of corpulmonale,and t-pa was lower in remission stage than in acute stage.the difference was significant(p.01).conclusion the unbalance between t-pa and pai can promote the formation of micro-thrombus and further exacerbate high pulmonary pressure.

目的 探讨血浆组织型纤溶酶原激活物及t-pa抑制物在肺心病急性加重期的变化。方法用发色底物法测定60例肺心病急性加重期的血浆t-pa及pai的活性,并与对照组55例肺心病缓解期的相应指标作比较。结果肺心病急性加重期患者pai显著高于肺心病缓解期,而t-pa低于肺心病缓解期,其差异具有非常显著性(p.01)。结论 t-pa及pai关系失衡,有助于动脉内微血栓形成,促进或加重肺动脉高压的形成。

Methods The Biotin-Strept -Avidin enzyme linked immunosorbent assay, spectrophoto-metric assay were used to measure the plasma levels of CT-1 and sICAM-1 in 56 patients with hypertension before and after treatment of Perinopril or Benidipine and 30 normal controls.

应用生物素-链霉亲和素酶联免疫吸附法对56例高血压患者应用培哚普利和贝尼地平治疗前后及30名正常健康人,测定血浆CT-1水平和血浆sICAM-1水平。

Rats administrating Aluminum and monosodium glutamate or sodium citrate had lower zinc level of red blood cell, but same levels in tissues comparing with only AlCl〓 and control.

试鼠同时服用铝和柠檬酸钠或谷氨酸钠将减弱血浆的抗氧化能力,血浆中MDA的量明显增加,SOD酶活力也显著降低(P.01)。

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