血浆的

Subject: The purpose of this.thesis is to explore the therapeutic mechanism of Radix Astragli injection from the point of view of modern medicine through studying its clinical therapeutic effect on patients with chronic glomerulonephritis characteristic of "qi" deficiency in lung - kindney , and its effect on urine protein, plasma albumin, plasma cholesterol, plasma creatinine, urea, hemodynamies urine2-microgiobulin , T lymphocyte , plasma endothelin , nitric oxide .

目的：本文通过研究黄芪注射液对肺肾气瘀证慢性肾小球肾炎患者的临床治疗效果以及对蛋白尿、血浆白蛋白、血浆胆固醇、血肌酐、尿素氮、尿β_2-微球蛋白(β_2-MG)、血流变学、T细胞亚群、血浆内皮素、一氧化氮的影响，从现代医学的角度探讨其治疗作用机理。

SC acan turn pneuma fine, add appetite, increase activity and improve color pattern and anischuria of RHR rats.SC didn't have evidence effect on SHR rats'body weight, but can increase RHR rats'body weight. 3.3.3 Find The effect on endothelin、nitrogen monoxidum、atrial natriuretic peptide and renin-angiotensin system of SC .

3.3.3三草降压汤对血浆内皮素、一氧化氮、心钠素及肾素-血管紧张素系统的影响 SC能明显降低SHR、RHR两种高血压大鼠模型血浆ET浓度、升高血浆NO浓度、调整二者的平衡，这可能是其发挥降压作用的重要机制。

Result:① In NC group,the levels of plasmic and lymphocytic NO were higher in the morning than those in the afternoon.② The plasmic and lymphocytic NO were significantly decreased in CAD patients then those in NC group (P＜0.01).③The physiological NO curve disappeard in CAD patients.The concentrations were no obvious changes and maintained lower levels in 24 hours.Conclusion:As similar as other endocrinic hormones,the NO secretion was not equal in 24 hours.

结果：①正常人24 h血浆和淋巴细胞中NO分泌呈上午高、下午低的趋势，晨6时最高，下午6时呈低谷，晚10时起又渐升高至早晨；②CAD心绞痛患者血浆和淋巴细胞中NO含量明显低于正常人，其差异具有统计学意义(P＜0.01)；③CAD患者失去了正常的NO生理性分泌曲线，血浆和淋巴细胞中24 h均在较低水平，波动范围不大。

We detected the result with the chi square test and concluded that it has statistical significance (P.05). Conclusion The detection of 1-3-β-D glucosan in patients blood samples is a both effective and quick way to diagnose the fungal rhinosinusitis. The positive rate of the way is about 90%.

本研究共计对20例真菌性鼻窦炎(19例为真菌球型，1例为慢性侵袭性真菌性鼻窦炎)患者及5例对照组患者血浆中1-3-β-D葡聚糖进行检测，发现其中18例真菌性鼻窦炎患者血浆中1-3-β-D葡聚糖的含量大于试剂盒的诊断标准10pg/ml，实验的阳性率为90%，血浆1-3-β-D葡聚糖水平可以用于诊断真菌性鼻窦炎。

According to the theory of the coagulation method it can be classified two types, one is the measure with photoelectric and nephelometric analysis; the other is the measure with double coil and a magnetic steel ball. coagulation method is physical quantity changes below coagulant acting on blood plasma, for example light、electricity、machine movement etc, and then the data is analyzed by computer to final result, so coagulation method is also called biology-physics method. Photics'blood coagulation apparatus determines coagulation by nephelometric'changes in the coagulate process.

凝固法是通过检测血浆在凝血激活剂作用下的一系列物理量的变化，由计算机分析所得数据并将之换算成最终结果，所以也可将其称作生物物理法；光学式血凝仪是根据凝固过程中浊度的变化来测定凝血的；双磁路磁珠法其原理是利用血浆凝固过程中，在其内部运动的物体所受阻力增加，因此通过测定受阻情况可以反映血浆凝固情况；另外近些年还有很多人采用压电石英晶体法来进行血凝研究。

Catecholamine requirements were significantlyless in the treated than in the nontreated patients.

记录基础值、体外循环开始前后、监护室直至术后第一天的血流动力学、内脏灌注压（胃动脉 CO2间隙）、肝功能（血浆谷胱甘肽α转换酶浓度）、肾功能（肌酐清除率、尿中 N-乙酰基-β-D-氨基葡萄糖酶）、心肌缺血（血浆肌酐激酶 MB 和肌钙蛋白 T 的浓度）、炎性反应（弹性蛋白酶、白介素-6和-8的血浆水平）和内皮细胞的完整性。

Results: Small round or linear haemorrhagic erosions were induced in the oxyntic glandular area after rats exposed to WRS. Meanwhile, GMBF decreased and NO contents in plasma and gastric mucosa increased significangly compared with those without WRS. L-NAME not only further decreased GMBF and inhibited the increases of NO contents but also aggravated the extent of gastric mucosal lesions. In contrast, L-Arg increased both GMBF and NO contents resulting in the lessening of mucosal injuries. All these changes were significant compared with control group.

结果：浸水束缚应激4 h可致严重的胃粘膜损伤，同时粘膜血流量明显下降，血浆及粘膜NO含量明显升高，与正常对照组相比差异非常显著（P＜0.01）；L-NAME明显加重粘膜损伤，并阻抑了应激所致的血浆及粘膜内NO含量的升高，使粘膜血流量更趋下降，与实验对照组相比差异显著（P＜0.05）；L-Arg可明显升高粘膜血流量及血浆、粘膜内NO含量，明显减轻粘膜损伤程度，与实验对照组相比差异非常显著（P＜0.01）。

Objective To establish the determination method of cefadroxil in healthy volunteers plasma. Methods Plasma protein was precipitated by perchloric acid (10%), and paraaminobenzoic acid was used as internal standard.

目的 建立用内标法测定人血浆中头孢羟氨苄浓度的HPLC-UV方法方法用10％高氯酸直接沉淀血浆蛋白，以对氨基苯甲酸内标，测定血浆中头孢羟氨苄的浓度。

It is also found that the level of IL-18BPa has a negative correlation with PASI score. This finding indicates that IL-18BPa as an inhibitor decreases in the plasma of psoriatic patients.

我们既往的研究发现银屑病血清中存在细胞因子异常，本文的研究发现银屑病患者血浆中IL-18BPa的浓度比正常人减少，进行期血浆中的浓度最低，退行期血浆中的浓度与正常人相近，与银屑病PASI评分呈负相关性，说明在银屑病外周血中存在抑制因子IL-18BPa的下降，IL-18/IL-18BP负反馈环路的异常，使Th1反应增强，可能在银屑病的发病机制中起到重要作用。

METHODS: After isolated the PBMCs and blood-plasma from adult human peripheral blood by Ficoll-Hypaque centrifugation, the PBMC culture procedure with or without the self-blood -plasma was applied to polarize T cells in vitro , these cells were polarized by PHA(20 mg/L),non-PHA respectively.

用Ficoll-Hypaque梯度离心法分离出正常成人抗凝外周血单个核细胞和血浆，将PBMC置于含或不含有自身血浆环境中，并在植物血凝素(PHA ，2 0mg L)的刺激下进行培养，培养 2 4、48、72h后收获细胞，分别用双色免疫荧光标记，以流式细胞术对CD4+ T细胞表达表面分子CCR3、CCR5进行分析。结果：CD4+ T细胞受自身血浆和PHA刺激后向Th1 Th2两个方向极化，2 4、48、72h后极化率分别达到(13 2 8± 1 5 9)%(12 70± 1 6 5 )%、(17 19± 1 0 3)%(17 5 0± 1 30 )%、(19 49± 2 87)%(18 5 8± 1 49)%；而只有PHA刺激的极化率很低，两组有显著性差异(P 0 1)；Th1∶Th2之比约等于 1。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

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