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Plasma Ang Ⅰ and Ang Ⅱ levels, chymase mRNA levels, arteries' PCNA positive percents and the thickness of carotid artery were measured.

通过测定血浆Ang Ⅰ及AngⅡ住水平、糜酶 mRNA表达水平、颈动脉细胞增殖核杭原阳性率及颈动脉各层厚度观察曲尼司特对犬颈动脉损伤后狭窄的作用。

Methods; In APS treatment group and control group, levels of insulin, C-peptide, myocardial enzymes, glycosylated serum protein and angiotensin were measured; Expression levels of chymase and angiotensin-coverting enzyme mRNA were detected by RT-PCR.

检测APS治疗组和对照组DM仓鼠的胰岛素、C肽、心肌酶谱、糖化血清蛋白和血浆。

Results As compared to DM control group, levels of GSP, myocardial enzymes and myocardial Ang Ⅱ were much lower in APS group, while levels of insulin, C-peptide and plasma Ang Ⅱ were the same. Levels of expression of collagen Ⅰ and the ratio of collagen Ⅰ/collagen Ⅲ in APS group were lower than those in DM group. APS group showed lower levels of chymase mRNA expression and activity than those in DM control group, while there was no diference in ACE mRNA expression and activity between the two groups.

结果 APS组血糖、糖化血清蛋白、心肌酶谱和心肌Ang Ⅱ水平较DM组显著下降,胰岛素、C肽、血浆AngⅡ水平和DM组无差异;APS组心肌Ⅰ型胶原表达和Ⅰ/Ⅲ型胶原比值较DM组显著下降;APS组chymase mRNA表达和活性均显著低于DM组,ACE基因的表达和活性与DM组无显著性差异。

While levels of insulin. C-peptide and plasma Ang Ⅱ were similar. APS group showed lower levels of chymase mRNA expression and activity than those of DM control group, while there was no diference in ACE mRNA expression and activity between two groups. Compared with DM group, expression level of p-ERK1/2 in APS group was much lower.

结果:APS治疗组GSP、心肌酶谱和心肌AngⅡ水平较对照组显著下降;血胰岛素、C肽、血浆AngⅡ水平与对照组无显著差异;APS组chymase mRNA表达和活性均显著低于对照组,ACE基因的表达和活性与对照组无显著差异;APS组心肌p-ERK1/2含量较对照组明显降低。

Maximum absorbency (reflecting the amount of coagulable plasmic fibrinogen in blood specimen).

最大吸光度(反映标本中凝固性血浆纤维蛋白原的量)。

Any of a class of proteins found extensively in blood plasma, milk, muscle, and plant seeds that are insoluble in pure water, soluble in dilute salt solution, and coagulable by heat.

一类蛋白,广泛见于血浆、奶、肌肉和植物种子中,不溶于纯水,溶于稀盐溶液,受热凝聚coagulable可凝结的。

Colorimetric method was used to determine PGE and MDA contents.

采用比色法分别测定了大鼠血浆中PGE含量及肝脏匀浆中MDA的含量。

Methods The plasma concentration of epigoitrin after ig administration with total alkaloids of Radix Isatidis was determined by HPLC method and the body temperature was recorded by electronic thermometer. The individual PK parameters were fitted using one compartmental model.

给大鼠ig板蓝根总生物碱,不同时间取血并对体温进行观察,采用高效液相法测定血浆中表告依春的浓度,用一房室模型计算药动学参数,采用3种药动学与药效学拟合模型,分别对药效学参数进行拟合。

The serous and coriaceous alcohol of depressed patient increases, coriaceous mellow eduction measures uric dissociate elevatory.

抑郁病人的血浆皮质醇增加、尿游离皮质醇排出量升高。

Methods The plasma concentrations of gliclazide were determined by HPLC with solide-phase extraction in 18 healthy male volunteers after an oral dose of 80 mg standard or tested formulations in crossways.

18名健康受试者单剂量交叉口服格列齐特供试制剂和参比制剂80mg后,用固相萃取高效液相色谱法测定血浆中格列齐特的浓度。

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