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Results: The concentrations of sIL-2R, IL-6 and ET in serum in asthma group were higher than that in control group (P.01), Manifestation of the lung tissue under electron microscope: the lung organism of the animal was infiltrated lamellarly by eosinophile granulocyte in the model set.

结果:模型组血浆中sIL-2R、IL-6和ET的含量与正常对照组比较明显增高(P.01),肺组织光镜和电镜下观察显示:模型组动物的肺组织可见嗜酸性粒细胞片状浸润,Ⅱ型细胞部分线粒体脊突消失、膨胀,板层小体减少,有较多排空现象。

METHODS: Eighty guinea pigs were randomized into control group, model group, salbutamol treated group and Maxin liquid treated group. Asthma model s were established by ovalhumin. The changes of eosinophile in bronchoalveolar lavage fluid, thromboxane B2 and 6-Keto-prostaglandin F1a in blood, the airway resistance and the pulmonary compliance were observed by Pap staining, radio-immunity , and pulmonary function test instrument of MIL type specially for experimental animal.

实验设正常对照组、模型对照组、复方麻辛组、沙丁胺醇组,选用豚鼠共80只,采用清蛋白造模,并运用巴氏染色法、放射免疫法、MIL型实验动物肺功能测量仪,分别检测肺泡灌洗液中嗜酸粒细胞数、血浆凝血恶烷(TXB2)、6-酮-前列腺素(6-K-PGF1a)以及清蛋白激发后气道阻力和肺顺应性。

A nonlinear regression is adopted to analyze the changes of plasma vitellogenin concentration in crucian carp via the environmental pollutant exposure concentration, and the concentration-response relationship is determined for the single chemical of estradiol (E2), ethynylestradiol (EE2), bisphenol A, 4-tert-octylphenol, and that of the mixed compounds at equipotent concentrations, the mixture being tested using a fixed-ratio design.

通过对鲫鱼血浆卵黄蛋白原含量的相对变化和暴露浓度的非线性回归分析得出17α-乙炔基雌二醇(EE2)、17β-雌二醇(E2)、双酚A、辛基苯酚及其等毒性固定浓度比例混合物产生雌激素效应的剂量-反应关系;应用相加作用数学模型根据单个化合物的数据预测混合物效应。

Rh blood; erythroblastosis, fetal; infant, newborn; plasma exchange; blood transfusion

本文对孕妇进行产前血浆置换降低血清中致病性Rh 抗体的效价,对产后患儿采用Rh阳性血代替Rh 阴性血换血治疗,收到满意的疗效。

At the age of 34 weeks, the plasma estradiol concentration of rat showed dose-dependent effects.

第34周血浆中雌激素浓度在各大组中皆呈现剂量依赖效应。

Rabbit anti-thrombosis in oral fungus polysaccharides 18.5mg/kg, can significantly extend the specificity of thrombus and fibrin thrombus formation time and shorten the length of thrombus, reduce the thrombus wet weight and dry weight, reduce platelet count, lower platelet adhesion rate and blood viscosity, and can significantly shorten the guinea pig euglobulin lysis time, lower plasma fibrinogen levels, elevated plasmin activity, results showed that the fungus polysaccharides significantly antithrombotic effect.

抗血栓形成兔口服木耳多糖18.5mg/kg,可明显延长特异性血栓及纤维蛋白血栓的形成时间,缩短血栓长度,减轻血栓湿重和干重,减少血小板数,降低血小板粘附率和血液粘度,并可明显缩短豚鼠优球蛋白溶解时间,降低血浆纤维蛋白原含量,升高纤溶酶活性,结果表明,木耳多糖有明显的抗血栓作用。

Rabbit anti-thrombosis in oral fungus polysaccharides 18.5mg/kg, can significantly extend the specificity of thrombus and fibrin thrombus formation time and shorten the length of thrombus, reduce the thrombus wet weight and dry weight, reduce platelet count, lower platelet adhesion rateand blood viscosity, and can significantly shorten the guinea pig euglobulin lysis time, lower plasma fibrinogen levels, elevated plasmin activity, results showed that the fungus polysaccharides significantly antithrombotic effect.

抗血栓形成兔口服木耳多糖18.5mg/kg,可明显延长特异性血栓及纤维蛋白血栓的形成时间,缩短血栓长度,减轻血栓湿重和干重,减少血小板数,降低血小板粘附率和血液粘度,并可明显缩短豚鼠优球蛋白溶解时间,降低血浆纤维蛋白原含量,升高纤溶酶活性,结果表明,木耳多糖有明显的抗血栓作用。

PART ONEInvestigation on Hp CagA+ strain infection condition and pathogenesis risk analyze in patients of carotid atherosclerosisObjective To observate pathological changes of carotid atherosclerosis as well as Hp infection situation, examinate blood fats, blood serum hs-CRP, blood plasma YKL-40, blood serum sCD14, analyze relations between Hp or Hp CagA+ strain and carotid atherosclerosis, and explore possible mechanism of carotid atherosclerosis caused by infection.

然后进行基础动物实验,应用Hp CagA+菌株干预高脂血症大兔,建立Hp CagA+菌株感染致兔颈动脉粥样硬化模型,进行血清Hp抗体、hs-CRP、血浆YKL-40水平检测、斑块内Hp DNA,进一步求证Hp CagA+菌株感染和颈动脉粥样硬化形成的相关性,Hp CagA+菌株感染是否可促进颈动脉粥样硬化的形成,深入探讨其可能机制,以期为颈动脉粥样硬化形成的病因学研究提供实验基础,为临床治疗颈动脉粥样硬化提供新的策略,从而完善其防治模式。

Results Therehave 2 cases phlebitis,9 cases fluid exosmose and 3 cases other adverse effects in A group; Therehave 8 cases phlebitis,18 cases fluid exosmose and 4 cases other adverse effects in B group.

将236例需行血浆置换的患者随机分为A和B两组,A组采用BD静脉密闭式留置针穿刺(120例),B组采用普通静脉穿刺针穿刺(116例)。

Moreover, IL-8 and α2-macroglobulin were analyzed as markers of pro-inflammatory cytokine production and plasma exudation.

IL-8 和α2-巨球蛋白分别作为分析促炎因子的产生和血浆渗出的指标。

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