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血栓形成

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Rabbit anti-thrombosis in oral fungus polysaccharides 18.5mg/kg, can significantly extend the specificity of thrombus and fibrin thrombus formation time and shorten the length of thrombus, reduce the thrombus wet weight and dry weight, reduce platelet count, lower platelet adhesion rate and blood viscosity, and can significantly shorten the guinea pig euglobulin lysis time, lower plasma fibrinogen levels, elevated plasmin activity, results showed that the fungus polysaccharides significantly antithrombotic effect.

血栓形成兔口服木耳多糖18.5mg/kg,可明显延长特异性血栓及纤维蛋白血栓的形成时间,缩短血栓长度,减轻血栓湿重和干重,减少血小板数,降低血小板粘附率和血液粘度,并可明显缩短豚鼠优球蛋白溶解时间,降低血浆纤维蛋白原含量,升高纤溶酶活性,结果表明,木耳多糖有明显的抗血栓作用。

Rabbit anti-thrombosis in oral fungus polysaccharides 18.5mg/kg, can significantly extend the specificity of thrombus and fibrin thrombus formation time and shorten the length of thrombus, reduce the thrombus wet weight and dry weight, reduce platelet count, lower platelet adhesion rateand blood viscosity, and can significantly shorten the guinea pig euglobulin lysis time, lower plasma fibrinogen levels, elevated plasmin activity, results showed that the fungus polysaccharides significantly antithrombotic effect.

血栓形成兔口服木耳多糖18.5mg/kg,可明显延长特异性血栓及纤维蛋白血栓的形成时间,缩短血栓长度,减轻血栓湿重和干重,减少血小板数,降低血小板粘附率和血液粘度,并可明显缩短豚鼠优球蛋白溶解时间,降低血浆纤维蛋白原含量,升高纤溶酶活性,结果表明,木耳多糖有明显的抗血栓作用。

Objective To discuss the clinical value of thrombolysis treatment of puerperium deep venous thrombosis of the lower limbs.

产褥期下肢深静脉血栓形成溶栓治疗临床探讨产褥期;下肢深静脉血栓形成;尿激酶目的:探讨产褥期下肢深静脉血栓形成的尿激酶治疗临床价值。

Research results indicate that varicosity can be treated by means of endovenous thrombus formation, blood vessel wall damnification and vessel enclosure induced by light absorption of haemoglobin irradiated by semiconductor laser.

研究结果表明:半导体激光进行腔内静脉照射,由于血红蛋白对光的吸收,可以引起静脉腔内血栓形成、血管壁损伤、血管闭合,实现对静脉曲张的治疗;激光照射导致静脉腔内血栓形成,与血栓性静脉炎的形成机制不同,并没有影响全身凝血功能。

Portal braches of 4-5 orders were found in all 19 cases of Child Grade I, with esophageal varices and paragastric varices and no fistula of hepatic artety-portal vein or portal vein embolus; Portal braches of 3-4 orders were displayed in all 16 cases of Child Grade II, besides esophageal varices and paragastric varices, cirsomphalos, retroperitoneal varices, paraesophageal varices, dilated azygos vein were also noted, some patients had fistula and portal vein embolus; in Child Grade III, portal branches of 3~4 orders were displayed with more collateral circulations, dilated left renal vein and paragallbladder varices were appeared, with fistula and portal vein embolus or not.

Child I级19例,肝内门静脉显影4~5级,侧枝循环以食管及胃周静脉曲张为主,没有肝动脉-门静脉瘘或门静脉血栓形成;Child Ⅱ级16例,肝内门静脉显影3~4级,侧枝循环除食管及胃周静脉外,脐周静脉、腹膜后静脉、食管周围静脉、奇静脉也有所开放,部分有肝动脉-门静脉瘘或门静脉血栓形成;Child Ⅲ级6例,肝内门静脉显影3~4级,侧枝循环开放较Ⅱ级增多,可出现左肾静脉扩张或胆囊周围静脉曲张,伴或不伴有肝动脉-门静脉瘘或门静脉血栓形成。16排螺旋CT门静脉造影对上述病例分级为一级17例,二级18例,三级6例,与Child分级结果高度相关。

Results Stable venous thrombus were observed in all inferior caval vein in thrombosis model group, and the proximal part of venous thrombus was unobstructed and consistent with the pathological change of venous thrombosis during acute stage in human body.

结果 采用改良法制作模型后,大鼠下腔静脉内不仅均形成稳定的血栓,而且形成血栓的血管段的近心端保持通畅,符合人体静脉血栓形成急性期的病理演变。

MAIN OUTCOME MEASURES: Adjusted rate ratios for all first time deep venous thrombosis, portal thrombosis, thrombosis of caval vein, thrombosis of renal vein, unspecified deep vein thrombosis, and pulmonary embolism during the study period.

主要观察指标:研究期间全部首次深静脉血栓形成、门静脉血栓形成、腔静脉血栓形成、肾静脉栓塞、非特异性深静脉血栓形成和肺栓塞调整比率。

Platelets play a central role in the spontaneous process of atherothrombosis and in the formation of thrombi following coronary stent implantation.

在动脉粥样硬化血栓形成的自发过程及血栓形成后的血栓冠状动脉支架植入术中血小板发挥中心作用。

Some cell dropped into the cavity and became free. Thrombosis or part organization could be seen. The internal elastic layer became thin, disappear or broken. In internal and middle layer existed fibroblasts, fibrocytes and collagen. Some of the wall indicated hyaline change, soomth muscle cell decreased greatly. The massive inflammatory cells invaded the middle and external layer. There were many foam cells in the capsule tissue. Cytoplasm was filled with fatty tissue and cholesterol. some cavities were full of thrombosis. Some thrombosis was fibrosis, the bottom was organization. The surface of the thrombosis existed red blood cell and librae.(2)Elatic fibrila staining: the internal elastic menbrane almost completely disappeared, the intact internal elastic menbran could be seen in the new small vessels.

动脉瘤管壁厚薄明显不均,全层或局部区域显著变薄向外膨出,内皮细胞空泡变性或坏死脱落,部分内皮细胞剥离并突入管腔成游离状,可见血栓形成及部分血栓机化;内弹力板变薄、消失或突然中断;在内膜及中膜部位主要为纤维母细胞、纤维细胞和大片胶原;部分动脉瘤壁呈均质状玻璃样变,平滑肌细胞明显减少;中膜和外膜可见大量的炎性细胞浸润;瘤壁组织有纤维母细胞、纤维细胞、大片胶原成分及较多泡沫细胞,胞浆内充满脂类物质及胆固醇结晶;部分动脉瘤腔内充满血栓,有的血拴已经纤维化,血栓基部机化,血栓表面有红细胞和纤维素。

Ruptured aneurysms may have high density blood in basal cisterns and sulci adjacent to them, in addition to subarachnoid hemorrhage.

破裂的动脉瘤可能在基底池及邻近脑沟内有高密度出血,未破裂的动脉瘤伴有部分或完全的血栓可以表现为稍高密度影,常常会有环状钙化壁或附壁血栓,增强扫描,伴有部分血栓的动脉瘤最特异的表现是靶征,完全血栓形成的动脉瘤可以有反应性的边缘强化,没有血栓形成的动脉瘤表现为明显均匀性管腔样强化。

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