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血小板减少

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The report makes a number of practical recommendations to eliminate early discontinuation of antiplatelet therapy.

这个报道列出了多条实用的建议来减少早期停用抗血小板治疗。

Result: Platelet aggregation rate of pretreatment and 8 weeks after treatment had significant difference, but hemostatic functions were similar. The incidence of cardiac event of two groups had no significant difference. The side effect of Clopidogrel and Ticlopidine had significant difference with granulocytopenia (3.4% vs. 0), gastrointestinal tract response (11.2% vs. 6.3%) and exanthem (9.0% vs. 3.2%) respectively, which need no drug withdrawal.

结果:治疗8周后的血小板聚集率与治疗前相比,差异具有显著性,而止血和血栓功能相似;治疗后两组心脏事件的发生率相似;噻氯匹定与氯吡格雷的副作用中性粒细胞减少(3.4%比0)、胃肠道反应(11.2%比6.3%)、皮疹(9.0%比3.2%),两组差异具有显著性,两组均无需要停药病。

In the experiment, an approach was made to the cause of DRP and the mechanism of it's prevention and treatmend by acupuncture. The experimental results indicated that in rat with diabetes,(1) plasma TXB2 and the ratio of TXB2 to 6-keto-PGF1α increased obviously, suggesting hyperfunction of platelet and injury to endothelial function, which tend to result in thrombosis;(2) erythrocytic filtration index increased remarkably, suggesting erythrocytic transforming and oxygen carring hypofunction, which is one of the factors leading to retinal anoxia;(3) hyperglycemia persisted, which is related to the thickening of basilar membrane of and the decrease of mural cell of retinal blood vessels;(4) serum growth hormone rose notably, which is not only one of the important factors causing basilar membrane thickening but also promotes the synthesis or Von Willebrand Factor that participates in a tendency to thrombosis.

本实验对糖尿病性视网膜病变(Diabetic Retinopathy,DRP)的成因以及针刺防治DRP的作用机理进行了探讨,实验结果表明:糖尿病大鼠(1)血浆TXB2及TXB2/6-ket0-PGF1α比值均显著升高,提示其血小板机能亢进,内皮细胞功能损伤,具有血栓形成倾向;(2)红细胞滤过指数(Filtration Index,IF)显著增高,提示其红细胞变形能力低下,携氧运行功能降低,是造成视网膜缺氧状态的因素之一;(3)呈持续高血糖状态,与视网膜血管基底膜增厚及管壁细胞减少有关;(4)血清生长激素(Growth Hormone,GH)水平明显升高,既是导致基底膜增厚的重要因素之一,又促进VWF合成,参与血栓形成倾向。

The main manifestations of typical IAHS are continuing hyperpyrexia, hepatomegaly and splenomegaly; laboratory findings are decrease of white blood count, hemoglobin or blood platelet, hypertriglyceridemia, liver disfunction, elevation of serum ferritin, and the hemophagocytes in bone marrow.

典型的儿童感染相关性噬血细胞综合征临床以持续高热、肝脾大为主要表现,实验室检查以白细胞计数、血红蛋白及血小板中两系或三系减少、低纤维蛋白血症、高三酰甘油血症、肝功能异常及血清铁蛋白升高,骨髓找到噬血细胞为主要特点。

It can be said thatblood stasis is the main pathology of DN,which is in line with Chinese medicine in "invalidism must accompany with blood stagnation""invalidism develop into collaterals" The view of blood stasis also match the modern medical point of hemodynamics changes and capillaries disease in patients with DN,such as increased hemorheology general index,blood viscosity and lipids, reduced kidney blood flow,platelet aggregation,sclerosis of blood vessels, renal microcirculation disturbance,even hypercoagulability.

可以说,瘀血阻络是糖尿病肾病的主要病机,这既符合于中医"久病必瘀""久病入络"的学术观点,也与现代医学认识的糖尿病肾病患者血液动力学和肾脏微血管病理学实验中,血液流变学的指数普遍升高、血浆粘度增加、血脂增高、肾血流量减少,血小板聚集、血管硬化,肾微循环障碍,甚至出现高凝状态的研究相当吻合。

Results:Compound lumbrical capsule can improve blood supply in ischemi c area of brain,increase blood inflow in brain blood vessel,decrease platelet ad he...

结果 :复方地龙胶囊能改善缺血引起的组织损伤,促进其梗死病灶的修复,能增加脑内血流量和减少其血管阻力,降低血小板的粘附率和延长体内血栓形成时间等。

Monkshood can inhibit the gathering of platelet and improve the microcirculation of ischemic tissue simultaneously.

同时人参皂甙能提供能量基质,增加底物水平磷酸化,促进三磷酸腺苷、磷酸肌酸的合成,保护细胞线粒体钙泵活性,减少线粒体膜磷脂降解,保护膜系统完整;附子能抑制血小板的聚集,改善缺血组织的微循环。

To compare it with the effect of aspirin in nondiabetic counterparts.

卒中和TIA通过两年的抗血小板治疗,每千人减少36

PLT and PCT of RA patients in active phase were increased, and have correlation with reactive indexes. It suggests that PLT, PCT can reflect reactiveness of RA as objective indexes. XFC can not only treat inflammation and delay the aggravation of RA patient by improving platelet ultrastructure.

活动期RA患者PLT、PCT显著升高,且与各活动性指标具有相关性,提示PLT、PCT可作为反映RA活动性的客观指标;新风胶囊能通过改善血小板超微结构从而减少CD62P释放来改善RA患者的关节炎症病变,延缓病情进展。

These results suggested that adrenocorticosteroid could improve the effect of platelet transfusion, increase CCI and recovery rate after transfusion, and decrease the incidence of transfusion refractoriness.

肾上腺皮质激素的应用可提高血小板输注的疗效,增加输注后的CCI及回升率,减少输注无效性的发生。

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