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The main adverse effects occurred in the patients were leucocytopenia and thrombocytopenia. No severe infection and chemotherapy-related death occurred.

不良反应主要为粒细胞及血小板减少等骨髓抑制,未出现严重感染,无化疗相关死亡。

Results:The overall response rate was 48.57%. The main toxicity was thrombocytopenia, leucocytopenia and peripheral nervous toxicity.

结果:全组CR 2例,PR 15例,有效率48.57 %,主要不良反应为白细胞及血小板减少,外周神经炎。

Of 150 cycles could be applied without dose modifications or delay. Leucocytopenia grade 3/4 was observed in 15%, anemia in 7%, and thrombocytopenia in 49% of the patients. Grade 3/4 nonhematologic toxicities (diarrhoea, nausea and neurotoxicity) occurred in one patient each (2%).

在150个疗程中,51%的疗程不需要调整剂量或延迟化疗时间。15%患者出现3/4级白细胞降低,7%患者出现贫血和49%的患者有血小板降低。2%患者(各有1例患者)出现3/4级非血液学毒性。

Smear diagnostic cell measures true sex to reduce disease or verdict (aplastic anemia and hematopoiesis bring down) false positive is respectively 29.0% with 37.1%, diagnose true sex to increase a disease (lienal function hyperfunction, special disease of disease of grow in quantity of the plaque that send a gender, grow in quantity of true sex red blood cell) false negative rate is 22.6% with 21.8%, diagnostic index performance is evaluated all not beautiful.

涂片诊断细胞量真性减少疾病或结论(再生障碍性贫血和造血减低)的假阳性分别为29.0%和37.1%,诊断真性增加疾病(脾功能亢进、特发性血小板增多症、真性红细胞增多症等)假阴性率为22.6%和21.8%,诊断指标性能评价均不佳。

The frequency of thrombocytopenia, prolonged prothrombin time, livedo reticularis and dental ulcer was higher in patients with anti-beta 2-GPI than those patients without anti-beta 2-GPI.

aβ2GPI阳性SLE患者血小板减少、凝血酶原时间延长、网状青斑、口腔溃疡发生率高于aβ2GPI阴性组,差异具有统计学意义。

Hematological changes in patients with SARS were common and included lymphopenia (68%-90% of adults; 100% of children, n=10), thrombocytopenia 20%-45% of adults, 50% of child...

SARS患者常常出现异常的血液学改变,包括淋巴细胞减少(在成人为 6 8%- 90 %;在儿童为 10 0 %,n =10 ),血小板减少(成人 2 0 %- 4 5 %,儿童 5 0 %),和白细胞减少(成人 2 0 %- 34%,儿童 70 %)。

Lymphopenia and hypocalcemia were the prominent laboratory findings. Severe thrombocytopenia was rarely observed.

实验室发现最明显的特征是淋巴细胞减少症和低钙血症,很少观察到严重的血小板减少症。

The most common adverse reactions in Study 1 were nausea, fatigue, infections, vomiting and anorexia and in Study 2 were nausea, fatigue, anemia, thrombocytopenia, ECG T-wave changes, neutropenia and lymphopenia.

研究1中最常见的不良反应是恶心,疲劳,感染,呕吐,厌食,在读二是恶心,疲劳,贫血,血小板减少,心电图T波变化,中性粒细胞和淋巴细胞。

And lymphopenia,andanemia;therefore,thesehematological parameters should be monitored during treatment with ISTODAX, and the dose should be modified, as necessary.

与ISTODAX治疗可引起血小板减少,白细胞减少,贫血,因此,这些血液学参数应在与ISTODAX监测治疗,剂量应修改,必要的。

Themostcommonadversereactions in Study 1 were nausea, fatigue, infections, vomiting and anorexia and in Study 2 were nausea,fatigue,anemia,thrombocytopenia, ECG T-wave changes, neutropenia and lymphopenia.

研究1中最常见的不良反应是恶心,疲劳,感染,呕吐,厌食,在读二是恶心,疲劳,贫血,血小板减少,心电图T波变化,中性粒细胞和淋巴细胞。

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