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血小板

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Objective: To study the effect of polysaccharide of laminarin 01(L01) effect on inhibit platelet function, protect endothelia cells in vivo and the vWF secretion of endothelia cells in vivo and vitro, thus providing an experimental basis for developing a new drug for antithrombosis.

目的:观察海带多糖L01对血小板功能和血管内皮细胞的体内保护作用以及对体外培养内皮细胞分泌血管性假血友病因子的影响,为研究和开发新型抗血栓药物提供理论和实验室依据。

The result showed that platelet, leucocyte, albumin and total protein were higher than pretherapy.

结果显示,血小板、白细胞、白蛋白、总蛋白较治疗前明显提高(P 0 5 )。

The elder age,underlying diseases,continued high fever, thrombocytopenia,leucocytosis and bilateral lung involvement were the risk factors.

伴发糖尿病与预后转归显著相关,外周血淋巴细胞数下降、血小板减少、血清LDH和CPK升高与预后均有相关性。

The prognosis is poor in patients complicated with diabetes,leucocytosis,lymphocytopenia,thrombocytopenia and elevated serum LDH and CPK.

伴发糖尿病,外周血白细胞增高、淋巴细胞下降、血小板减少,血清LDH和CPK升高的患者预后转归不良。

The main side effects were leucopenia and thrombocytopenia,but they were tolerable.

最主要的毒副反应为白细胞及血小板降低,但均可耐受。

The main side effects were leucopenia and thrombocytopenia.

毒副作用以白细胞和血小板下降为常见,但均可耐受。

No one died or discontinued therapy for adverse effects, and 4 out of 67 (5.97%) had grade 3 or 4 thrombocytopenia and/or leucopenia in the STI571 group.

甲磺酸伊马替尼组治疗期间没有患者因药物副作用而停药、死亡,4例(5.97%)发生Ⅲ/Ⅳ级白细胞和/或血小板减少。

Diabetic Patient this disease incidence of a disease is apparently elevatory also, because Diabetic Much companion has tall lipemia, Hypertensive Reach plaque activation to increase, these all quicken the formation of sclerosis of arterial congee appearance and its thrombus.

糖尿病患者该病发病率也明显升高,因为糖尿病多伴有高脂血症、高血压及血小板活化增加,这些均加速动脉粥样硬化及其血栓的形成。

The method is right tall lipemia group (81) contrast with normal blood fat group (65), with analysis of appearance of gas phase color atlas all sorts of armour ester change the content of fatty acid of plaque phosphatide film, determine with standard method the thrombosis in blood endangers factor, serum is the same as model half Guang ammonia is acerbity and element of 11- dehydrogenation thrombus B2(TXB2), analyse the dependency between both with multivariate and linear regression.

方法对高脂血症组(81例)和正常血脂对照组(65例),用气相色谱仪分析各种甲酯化血小板磷脂膜脂肪酸的含量,用标准方法测定血液中血栓形成危害因子,血清同型半胱氨酸及11-脱氢血栓素B2(TXB2),并用多元线性回归分析二者之间的相关性。

Objective To investigate the effect and mechanism of lipoprotein[Lp] on platelet thrombosis.

目的研究脂蛋白[Lp]对血小板血栓形成的作用及其机理。

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