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Results In those patients with marrow invasion , 4 cases in I phase(4.2%),12 cases in II phase(12.6%),36 cases in Ⅲ phase(37.9%)and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%), 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal(31.6%)and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.

结果发生骨髓侵犯病例中I期4例(4.2%), II期12例(12.6%),Ⅲ期36例(37.9%),Ⅳ期43例(47.4%);病理类型以小淋巴细胞性,弥漫型裂细胞性(改为:弥漫性大B细胞型淋巴瘤)和淋巴母细胞性淋巴瘤多见;纵隔淋巴结肿大、脾脏肿大和脾受侵患者易发生骨髓侵犯;骨髓侵犯患者外周血中贫血56例(58.9%),血小板减少42例(44.2%),白细胞减少27例(28.4%),白细胞增高49例(51.6%),以贫血多见;三项均异常30例(31.6%),至少一项不正常65例(68.4%),淋巴瘤细胞白血病患者外周血象异常发生率高于骨髓浸润患者,尤其是白细胞增高或三项均异常者更常见于白血病;66例(69.5%)外周血分类中发现异常细胞;骨髓侵犯化疗有效率65.2%,中位生存期11.5个月。

Results In those patients with marrow invasion , 4 cases in I phase(4.2%),12 cases in II phase(12.6%),36 cases in Ⅲ phase(37.9%)and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%)恶性淋巴瘤症状, 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal(31.6%)and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.

结果发生骨髓侵犯病例中I期4例(4.2%), II期12例(12.6%),Ⅲ期36例(37.9%)恶性淋巴瘤分期,Ⅳ期43例(47.4%);病理类型以小淋巴细胞性,弥漫型裂细胞性(改为:弥漫性大B细胞型淋巴瘤)和淋巴母细胞性淋巴瘤多见;纵隔淋巴结肿大、脾脏肿大和脾受侵患者易发生骨髓侵犯;骨髓侵犯患者外周血中贫血56例(58.9%),血小板减少42例(44.2%),白细胞减少27例(28.4%),白细胞增高49例(51.6%),以贫血多见;三项均异常30例(31.6%),至少一项不正常65例(68.4%),淋巴瘤细胞白血病患者外周血象异常发生率高于骨髓浸润患者,尤其是白细胞增高或三项均异常者更常见于白血病;66例(69.5%)外周血分类中发现异常细胞;骨髓侵犯化疗有效率65.2%,中位生存期11.5个月。

Objective To study the treating effect of middle and high doses of acetone and aether extracts from Rumex.

目的:研究羊蹄根丙酮、乙醚提取物对小鼠血小板减少症的治疗作用。

The mechanism by which this occurs may be through competitive inhibition of the acetylation site of cyclooxygenase in the platelet.

这一制度出现的,可通过竞争性抑制乙酰网站化酶与血小板

OBJECTIVE:To study the effects of acetylsalicylic magnesium-ureaon thrombosis and platelet aggregation and its mechanism in animals.

目的:观察乙酰水杨酸镁-脲对血栓形成及血小板聚集的影响并探讨其机制。

Methods: According to their urinary albumin excretion rate, Diabetes mellitus patients with micrangium disease were further divided into three subgroups: normo-albuminuria、micro-albuminuria and clinical proteinuria; The expression of platelet membrane α-glucoprotein (CD62p) and cytolysosome protein (CD63)、platelet aggregation function and mean platelet volume was determined with flow cytometer、blood aggregation analyzer、automated blood cell counter (MEK-6318K) respectively, and compared with 30 normal controls.

对糖尿病微血管病变患者按尿清蛋白排泄率分为正常清蛋白尿组、微量清蛋白尿组、临床清蛋白尿组三组,分别用流式细胞术、血液聚集仪、全自动血细胞分析仪测定血小板内α-颗粒膜蛋白(CD62p)、溶酶体蛋白(CD63)的表达及血小板聚集功能和平均体积,并与30例正常对照组比较。

Objective:To investigate platelet transfusions after chemotherapy on tumor reduction in platelet effect.

目的:探讨输注血小板对肿瘤化疗后血小板减少的疗效。

The inhibitory effect against platelet aggregation induced by ADP of 4 watersoluble components was studied in vitro.

丹参4种水溶性单体对血小板功能的影响研究结果表明,丹参酚酸B、迷迭香酸、丹参素、原儿茶醛均具有体外抗ADP诱导的兔血小板聚集活性。

This flow chamber allows realtime observation and record of the interaction between platelets and vWF under welldefined shear rate.This approach can be applied to platelet adhesion research.

本研究方法可以在精确剪切率和不同流态的流体环境条件下,实时地观察、记录血小板与vWF相互作用的情况,为血小板各种生理功能的研究以及相关药物的研究应用创造条件。

Methods The platelet NO production in 21 hypercholesterolemia patients and 26 normal individuals was assayed by spectrum, the NOS activity and the transportation of L Arg were determined by 3H labelled L Arg.

采用比色法检测 2 1例HC患者和 2 6名健康体检者血小板的NO水平,采用放射性核素(3H L 精氨酸)标记法检测血小板一氧化氮合成酶及L Arg转运系统活性。

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