血友病

Estimates range from 6,000 to 10,000 hemophiliacs in the United States becoming infected with HIV.

在美国，估计有6000到10000的血友病患者被感染了HIV。

This means they can suffer from internal bleeding - bruises and sprains can be much more serious for haemophiliacs.

这就意味着他们要遭受内部出血-瘀伤的痛苦，并且对血友病患者来说，扭伤会比正常人更严重。

However, about 2,000 people in the United States each year suffer from moderate and severe forms of the disease in which bleeding can be excessive if not treated and possibly cause delayed wound healing.

但是，在美国每年约有2，000名中重度的血管性血友病患者，如果不治疗将过度出血并可能导致创伤恢复延迟。

Hemophilia B is an X-linked bleeding disease, caused by the mutations of human coagulation factor IX gene located in chromosome X. It results in a dramatic decline of hFIX quantity or clotting activity in plasma, and the intrinsic clotting pathway is affected seriously.

血友病B是一种性连锁隐性遗传病，其发病机制是位于X染色体上的人凝血因子IX基因发生了突变，导致血浆中hFIX含量或活性大幅下降，从而使得内源性凝血途径受到阻碍，无法进行正常的凝血。

METHODS: The presence and number of recently developed extra-articular manifestations and a weighted EAM score, as well as the levels of serological markers, were compared between 31 patients with RA with histologically proven vasculitis and 50 patients with RA in whom vasculitis could not be documented histologically. The following markers were evaluated: circulating immune complexes, complement components C3 and C4, class-specific rheumatoid factors, antineutrophil cytoplasmic antibodies, antinuclear antibodies, antiendothelial antibodies, circulating intercellular adhesion molecule-1 and -3, circulating vascular cell adhesion molecule and E-selectin, cellular fibronectin, von Willebrand factor antigen, and C reactive protein.

对比组织学上已证实有血管炎的31例 RA 例和组织学上无血管炎的50例 RA 患者间的临床及血清学标记物，这些资料包括最近发生的关节外表现数量、关节外表现加权得分、循环免疫复合物、补体 C3和 C4、类风湿因子（ IgM-RF，IgG-RF，IgA-RF ）、抗中性粒细胞胞浆抗体、抗内皮细胞抗体、循环细胞间粘附分子-1和-3、循环血管内皮粘附分子和 E-选择素、细胞纤连蛋白、假性血友病因子抗原（ von Willebrand factor antigen ）及 C-反应蛋白。

Methods Forty-one patients were divided into two groups: stable angina group and acute coronary syndrom group. The levels of UA, alpha-granule membrane protein 140 (GMP-140), von Willebrand factor, plasminogen activator inhabitor type-1 (PAI-1), thromboxane B2 (TXB2), C-reactive protein were measured. Then all data as well as intercommunication were evaluated among two groups.

41例老年冠心病住院患者分为稳定型心绞痛组和急性冠脉综合征组，测定UA、血小板α-颗粒膜蛋白(GMP-140)、血管性假性血友病因子、纤溶酶原激活物抑制物－1(PAI-1)，血栓素B2(TXB2)、C-反应蛋白。

Sera from 18 Chinese haemophiliacs treated with factor Ⅷ produced in USA from 1982 to 1984 were tested for antibody to LAV/ H T L V-Ⅲ by ELISA. Four patients ( 22.2%) showed strong positive results which were confirmed by immunofluorescence test and Western blot,but none of them has developed symptoms related to AIDS.

对浙江省1982～1984年注射了美国产浓缩Ⅶ因子制剂的18例血友病患者，用酶联免疫吸附法检测了血清中淋巴腺病病毒/人T细胞Ⅲ型病毒抗体，发现4例阳性，并经免疫荧光试验和Western印迹法证实。2例应用了国产浓缩Ⅷ因子者抗体阴性。

Myoblasts can synthesize and secrete biologically active factor, and it is an ideal target cell in hemophilia B gene therapy.

成肌细胞具有合成、分泌活性FⅨ的功能，可作为血友病B基因治疗的一种理想靶细胞。

He Tsarevich was another victim of the dreaded disease inherited from his great-grandmother Queen Victoria, Hemophilia.

sarevich 是畏惧的疾病的其它受害者被继承从他的曾祖母女王维多利亚，血友病。

Newswise - Scientists at the Albert Einstein College of Medicine of Yeshiva University have shown for the first time that transplanted cells can cure hemophilia A (the most common form of the disease) in an animal model.

newswise -科学家爱因斯坦医学院的大学神学院的显示，对于第一次移植的干细胞可以治疗血友病A在动物模型。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。