血压

On admission, he was alert and fully oriented. His temperature was 38°C, pulse was regular (90/min), blood pressure was 150/80mmHg. His speech was severely dysarthric but he could name, repeat, read, and follow instructions. His cranial nerves and fundoscopic examination were normal. His gait was wide based and unsteady. He had four sided mild weakness, which was prominent on the right.

入院时体格检查示：T 38°C，脉搏规律90次/分，血压150/80mmHg；双下肢前方见暗红色疼痛性结节性红斑；眼科检查未见眼葡萄膜炎；患者主诉阴囊发热、疼痛，检查时见双侧附睾肿胀、质硬、明显触痛，呈附睾炎表现。

Essential hypertension caused by neurovascular compression of the left ventrolateral medulla was associated with malbalance of vasomotor center in the dorsal medulla. The possible pathogenesis was the following:① An irritation of the left RVLM by pulsatile compression of an ectatic vessel would increase activity of central sympathetic neuron.② Neurovascular compression at the REZ of the cranial nerves Ⅸ and Ⅹ decreased excitation of parasympathetic nerve.③ Decreased sensitivity of afferent inputs to neuron of nucleus tractus solitarii in the sensory area lead to hyperactivity of central sympathetic nervous system due to pulsatile compression of the left RVLM.④ Neurocompression of the left RVLM and REZ in the left cranial nerves Ⅸ and Ⅹ lead to an overactivity of central renin angiotensin system.

3，结论：左侧延髓腹外侧Ⅸ、Ⅹ颅神经REZ动脉血管压迫所导致的高血压的发生与左侧延髓血管运动中枢对血压的调节失衡有关，其可能机制是：①左侧RVLM在搏动性血管压迫刺激下，中枢交感神经元活性增高；②左侧Ⅸ、Ⅹ颅神经REZ受压导致副交感神经兴奋性降低；③感受区孤束核神经元接受迷走神经传入冲动的敏感性减低，导致中枢交感神经活性增高；④左侧RVLM及Ⅸ、Ⅹ颅神经REZ受压引起中枢RAS活性增加。

With the development of lesion inautonomic nervous system, i.e. the elevation of baroreflex set point, blood pressureincreases to stage 1 hypertension and worsens. Furthermore, the role of the effectors,including PVR, ventricular end-systolic elastance, venous unstressed volumes and heartrate, in the regulation of hypertension was analyzed. The results exhibit that the ANSregulation on hypertension works mainly by the reduction of PVR and the increase ofvenous unstressed volume.

随着自主神经系统损坏程度的不断加重，即工作调定点进一步升高，血压水平上升到了1级高血压并趋于严重；研究了神经调节的各效应器(外周血管阻力、心肌最大弹性度、心率和静脉非压力容积)对高血压的作用，表明神经调节机制对高血压的调节主要是通过降低外周血管阻力和增加静脉非压力容积实现的。

In this context, we have reported recently that the volume of myocardial tissue occupied by perimysial and endomysial collagen was lower in hypertensive patients with HF and depressed ejection fraction, than in hypertensive patients with HF and preserved ejection fraction and normotensive subjects.56 Of interest, the interstitial and perivascular accumulation of collagen fibres was abnormally high in the two groups of patients.

在这种情况下，我们已经说了占用体积perimysial心肌组织人肌内膜胶原水平低的高血压患者用高频和沮丧的射血分数在高血压患者的心力衰竭和保存被罚出场分数与正常血压subjects.56舒张压的利息、间质和血管堆积过高的胶原纤维是在两组病人。

Objective The anticogant to the endotheliotoxin receptor is a promising drug to treat with the pulmonary arterial hypertension therotically.But in our country there was few systemical clinical trial about the drug used in the disease.We study the curative effect and the side effect of an anticogant to the endotheliotoxin receptor-Tetramethylpyrazine on the pulmonary arterial hypertension.Methods The64newborn patients were continually main line the tetramethylpyrazine by the mini pump and stimutaneously treated with the respiratory machine.The injec-tion speed was controlled from5μg/kg·min to10μg/kg·min,or to20μg/kg·min.

目的 探讨内皮素受体拮抗剂—阿魏酸钠微量泵持续静脉注射治疗新生儿肺动脉高压的疗效和不良反应方法对64例肺动脉高压的新生儿在呼吸机械通气的情况下同时用微量泵持续静脉注射阿魏酸钠，阿魏酸钠微量泵静脉注射的速度由5μg/开始，在保证体循环血压的基础上可以逐渐加量至10μg/，直至20μg/。

In conclusion, catechins supplementation can improve endotoxic hypotension, its mechanism need further investigated.

总结而言，儿茶素补充能够改善内毒素性低血压反应，其机制需进一步探讨。

Increased H2S production might be partly involved in the pathogenesis of hypotension and tissue inflammatory damage during endotoxic shock.

2内毒素休克大鼠严重低血压和组织炎症损伤的发生与H2S生成增多有关。

It has no apparent influence toward blood pressure,conventional blood examination,conventional urea-examination,conventional excrementitious examination,liver function (transfer ammonia-lyase,total bilirubin,white protein) and kidney function.It shows no obvious poisonous side effect in clinical experiments.

培元通脑胶囊对血压、血常规、尿常规、粪常规、肝功能(转氨酶、总胆红素、白蛋白)、肾功能、心电图等均无明显影响，在临床试验中亦未出现明显的毒副反映。

Methods 106 hypertensive patients were randomized into lacidipine group (n=53) and fosinopril group (n=53). The excretive rate of urinary albumin, the clearance endogenous creatinine, and blood and urine β2 microglobulin (β2-MG) were detected before and after treatment.

选择106例高血压2~3级患者，随机分为拉西地平组和福辛普利组，治疗前后检测血压和尿蛋白排泄量、内生肌酐清除率、血清肌酐、血清尿素氮及血、尿β2微球蛋白(β2-MG)，采用彩色多普勒超声检查测量肾动脉管壁厚度及内径。

Methods The blood pressure, eye ground, urinalysis, renal function and extrarenal presentations of malignant hypertension patients, who had been hospitalized in recent eleven years, were analyzed retrospectively.

回顾性分析我院肾内科 11年来收治的 2 7例(男 2 1例，女 6例，年龄 19～ 5 1岁)MHPT患者的血压、眼底、尿和肾功能变化，对比分析原发性和肾实质性MHPT的临床与肾脏病理改变。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。