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After 6 months MCS and BS decreased a little more rapidly but were still above 10 Mpa after 12 months. Conclusion can be drawn that CBAB implanted had no remarkable negative affection on the concentration of Ca and P in blood and tissue response around, and didn't result in ectopia osteogenesis. The biomechanical strength decreased gradually and continuously.

提示:CBAB植入兔肌肉内对外周血Ca、P浓度无显著不良影响,未见感染等不良反应,也未见异位成骨,生物力学强度缓慢减低,有较好的连续性。

And it has half-life of elimination of 70-90 minutes.

密钙息的绝对生物利用率约为70%。1小时内其血药浓度可达高峰,其半衰期为 70~90分钟。

The biocompatibility of poly(3-hydroxybutyrate-co-hydroxyocatanoate), a new biodegradable co-polymer scaffold, was evaluated with a series of tests, including cytotoxicity test, acute systemic toxicity test, hemolysis test, pyrogen test, genetic toxicity test, intracutaneous stimulation test and subcutaneous implantation test.

文章选用细胞毒性实验、急性全身毒性实验、溶血实验、热源实验、皮内刺激实验、遗传毒性实验和皮下植入实验等7个生物相容性实验对生物可降解支架材料羟基丁酸与羟基辛酸共聚体的生物相容性进行评价。

Fig 1 Negative control Female umbilical cord sample has no Y-specific signal after in situ hybridization with the biotinylated Y-repeated sequence DNA probe PY3.4 Fig 2 Positive control Flow-sorted male umbilical cord cells hybridized to Y-specific DNA probe PY3.4,Every cell contains a Y-specific signal Fig 3 Fetal cells sorted from maternal blood Flow-sorted cells from a pregnant woman at 20 weeks of gestation hybridized to Y-specific DNA probe PY3.4,containing a Y-specific signal Fig 4 The result of polymerase chain reaction Lane 1:male umbilical cord NRBCs sorted by FITC-conjugated anti-monoclonal glycophorin A;Lane 2:sample of 2;Lane 3:male umbilical cord NRBCs sorted by FITC-conjugated anti-CD36;Lanes 4-5:samples of 1 and 3;Lane 6:50 cells of male;Lane 7:5 cells of male;Lane 8:200ng male DNA(positive+control);Lane 9:nonpregnant female DNA(negative+control);Lane 10:ΦX174 HaeⅢ Maker,271bp:amplified band of Y-specific gene SRY;383bp:amplified band of human β-globin gene

图1 阴性对照女性脐带血标本,经与生物素标记的Y-染色体重复序列DNA探针原位杂交后未见Y-染色体特异信号图2 阳性对照分选的男性脐血细胞经与Y-特异DNA探针杂交后,每一细胞都含有Y-染色体特异信号图3 母体外周血中分选的胎儿细胞从一位妊娠20周的孕妇外周血中分选出的细胞经与Y-特异DNA探针杂交细胞中含有Y-染色体特异信号图4 聚合酶链反应结果 1:GPA-FITC单抗分选男胎脐血NRBCs;2:2号标本;3:CD36-FITC单抗分选男胎脐血NRBCs;4、5:1、3号标本;6:50个男性细胞标本;7:5个男性细胞标本;8:200ng男性DNA;9:未孕女性DNA;10:ΦX174 HaeⅢ标准,271bp:为SRY基因扩增带;383bp:为人β-珠蛋白基因扩增带内参照

Keen Scent: A vampire bat can notice creatures by scent in a 180-foot radius and detect blood in the air at ranges up to a mile.

敏锐嗅觉:吸血蝙蝠能够注意到半径180尺内的生物气味,并且空气中鲜血的气味范围可以达到1里。

The biocompatibility of self-designed hydroxyapatite/poly rods was evaluated both in vitro and in vivo including Ames test, micronucleus test, acute and subacute systemic toxicity test, hemolysis test, hemopexis test and long-term muscle and bone implant test.

对自行研制的可吸收羟基磷灰石/聚DL-乳酸复合骨折内固定材料进行了一系列生物相容性实验,包括Ames实验、微核实验、急性和亚急性毒性实验、溶血实验、凝血试验和肌肉、骨内长期植入实验。

The biocompatibility of self-designed hydroxyapatite/poly rods was evaluated both in vitro and in vivo including Ames test, micronucleus test, acute and subacute systemic toxicity test, hemolysis test, hemopexis test and long-term muscle and bone implant test.

对自行研制的可吸收羟基磷灰石/聚DL-乳酸复合骨折瘦身内固定材料进行了一系列生物相容性实验,包括Ames实验、微核实验、急性和亚急性毒性实验、溶血实验、凝血试验和肌肉乙肝、骨内长期植入实验。

Objective To investigate the distribution statistics of tiny biology-eperythrozoon in leucocytes,and extends to the distribution of this tiny organism among animals and plants.Methods Human or animal blood plasma,or dissolved whole blood and plant juice were taken to make a slice,then oil microscope was used to observe.

目的 调查微小生物—附红细胞体在白细胞内的感染分布,并延伸调查部分动、植物内微小生物的分布方法用人、动物血浆、全血溶血液和植物内汁液制作压片后油镜观察。

Methods Explore the optimal concentration of phurbol-12-myristate-acetate and calcium ionophore (A23817) inducing time, and optimal concentration of biotinyl sheep anti mouce IgG (bio-SAM-IgG) and horse radish peroxidasestreptavidin. The CD4(superscript +) cell enriched from peripheral blood mononuclear cells using solid phase anti-CDs monoclonal antibodies were induced by PMA and A23817 under influence of monensin and harvested in vary hours.

从健康人外周血单个核细胞中富集CD4细胞,加入莫能霉素,用不同浓度的佛波醇酯和钙离子载体(A23817)诱导CD4细胞不同时间,比较其胞内表达白细胞介素-2(IL-2)/白细胞介素-4(IL-4)的细胞百分率,确定最适诱生条件;用不同稀释度的IL-2McAb、IL-4McAb、不同浓度的生物素化羊抗鼠IgG(bio-SAM IgG)和辣根过氧化物酶标记的链霉亲和素作棋盘配比试验,确认McAb、bio-SAM IgG和HRP-SA的最适浓度,根据上述结果建立了检测细胞内细胞因子的BSA-ICC法。

To study the effects on the body of animals after incorporation of 3H-TdR and its mechanism, the laws of distribution A retention and absorbed dose in blood , thymus, spleen, femur, heart, lung,kidney, liver, brain , spermary , small intestine and muscle were detected by liquid scintillation counter after 3H-TdR was injected into the tail vein of mouse; the process of dynamic incorporation of in the lymphocytic cell nucleus of blood , thymus , spleen and the nucleus of femur was monitored; the absorbed dose in the cell nucleus was estimated; the influence to RNA"s synthesizing and cell"s survival was observed using the technology of CLSM; A segment of Egr-1 gene was cloned with reverse transcriptase- polymerase chained reaction, the influence to the expression of Egr-1 gene in the spleen cells was observed.

为了探讨有机结合氚内污染对生物机体的影响及其作用机理,本课题应用均相液体闪烁测量技术研究了氚标记胸腺嘧啶核苷(~3H-TdR)经尾静脉注入小鼠机体后,在血液、脑、胸腺、心脏、肺脏、肝脏、脾脏、肾脏、小肠、睾丸、肌肉和股骨共12种组织器官的生物动力学分布规律及其吸收剂量;应用纸片法液体闪烁测量技术研究了~3H-TdR内污染在外周血、胸腺和脾脏淋巴细胞及骨髓细胞的动态滞留规律,估算了细胞核的吸收剂量;应用共聚焦显微镜观察了~3H-TdR内污染对脾细胞核酸合成及其存活率的作用,应用反转录PCR技术研究了~3H-TdR内污染对脾细胞早期生长反应基因-1(Egr-1)转录表达的影响。

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