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Objective: To discuss expression levels of MMP10 gene and protein in human spontaneous abortion deciduas and its significance in clinic.

目的:探讨基质金属蛋白酶10(MMP10)基因及其蛋白在人自然流产蜕膜中的表达水平及临床意义。

Objective To analyze the levels of cell adhesion molecules on deciduas from patients with pregnancy induced hypertension.

目的 分析妊高征患者蜕膜粘附分子表达的变化。

RT-PCR were used to detect the expression of PRmRNA in the deciduas.

运用RT-PCR方法检测蜕膜PRmRNA的表达。

In experimental rats deciduas of implantation sides were obtained by 8th day and 15th day of pregnancy.

结果各辐照组LIF和MMP-9早孕蜕膜组织中表达明显小于对照组(p〈0.01),并随声强的增强而表达逐渐减弱。

Methods: By using immunohistochemical analysis EMMPRIN expressions in chorionic villi and deciduas were evaluated.

目的 探讨先兆流产时绒毛及蜕膜组织中细胞外基质金属蛋白酶诱导因子的表达情况。

Differential proteins found in deciduas from patients with severe preeclampsia might play an important role in the pathogenic process of preeclampsia.

子痫前期重度患者蜕膜组织中存在差异蛋白,这些蛋白质在子痫前期的发病过程可能起重要作用。

METHODS: The deciduas from 5 normal women of fullterm pregnancy and 5 preeclampsia patients were collected to obtain the total proteins.

收集5例正常足月妊娠妇女和5例足月子痫前期重度患者胎盘母面及宫壁上的蜕膜组织,提取总蛋白。

The positive staining of EMMPRIN was evident in deciduas of all the samples, but there was no significant difference between threatened abortion and normal early pregnancy.

EMMPRIN在先兆流产组、正常妊娠组蜕膜组织中均呈阳性表达,且二者表达的EMMPRIN无明显差异。

The immunohitochemisty was used to determine the histological localization of TNFR1 stainning in 31 abortion and 30 control group deciduas.

结果:(1)流式细胞仪检测流产组、对照组蜕膜组织中TNFR1的表达含量分别为(16.48±7.2)%,(12.52±5.6)%,流产组高于对照组,差异具有显著性(t=2.24, P.05)。

Methods immunohistochememstry(s-p technique) and pathologic image semi-quantification were used to detect the expression of mmp-9 and timp-1 in endometrium of 30 unexplained infertility patients and 20 normal early pregnant deciduas and 20 normal endometrium.

目的 检测基质金属蛋白酶-9(mmp-9)和组织金属蛋白酶抑制物-1(timp-1)在不明原因不孕、正常早孕蜕膜组织和正常子宫内膜中的表达,探讨其与不明原因不孕关系。

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