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Objective To study the effects of mifepristone on the expression of IL6 in human decidua and chorion of early pregnancy in order to explore the molecular immune mechanism of mifepristoneinduced abortion.

目的 观察IL6在早孕绒毛、蜕膜组织中的表达及米非司酮对其表达的影响,探讨药物流产的分子免疫作用机制。

AIM: To detect the expressions of insulinlike growth factorⅠ in villus and IGFII in decidua and the levels in mother serum, and to explore their relationship with the embryogenesis of early pregnancy.

目的:探讨胰岛素样生长因子I和II在正常胚胎发育及早期胚胎发育终止绒毛及蜕膜组织中的表达及其在母体血中水平的改变与胚胎发育的关系。

Our results demonstrate that chemokines present in the uterus can support pbNK cell migration through human endothelial and stromal decidual cells.

我们的研究结果表明子宫中的化学因子支持pbNK细胞通过人的内皮和间质蜕膜细胞迁移。

Abstract〕 objective to investigate the separation methods and growth conditions of decidual dendritic cells, and establish the ground work for the research of dendritic cell's functionary mechanism in maternal immunity and tolerance to the fetus.

目的:探讨人子宫蜕膜树突状细胞的分离方法和诱导培养的最佳条件,为研究树突状细胞在母胎免疫耐受中的作用奠定基础。

Fig. 2.Expression of Fas and FasL mRNA in human deciduas during the early stage of pregnancy.

我们的研究结果(图2)显示,在人妊娠早期第6周的时候,在母体蜕膜中有大量细胞表达Fas 和FasL mRNA。

NK cells participate in the deciduas development and uterine blood vessels recasting, so it is an important immune cells in normal pregnancy.

NK细胞参与蜕膜发生及子宫血管的重铸,在正常妊娠中起着十分重要的作用。

AIM: To investigate the expression and histological localization of tumor necrosis factor receptor 1 (TNFR1) in deciduas of unexplained early spontaneous abortion.

目的:探讨肿瘤坏死因子受体Ⅰ(tumor necrosis factor receptor 1, TNFR1)在蜕膜中的表达及其与不明原因自然流产的关系。

Methods Expressions of TGF -β1 mRNA and its receptors were detemined in villi and deciduas by semi-quantitative reverse transcriptional-polymerase chain reaction from 38 cases of spontaneous abortion women and 35 cases of normal early pregnancy women.

应用半定量逆转录-聚合酶链反应技术,检测 38 例 RSA 患者和 35 例正常早孕妇女的绒毛及蜕膜组织中 TGF -β1 mRNA,TβRmRNA 的表达情况。

Objective: To investigate the expression and histological localization of tumor necrosis factor receptor 1 (TNFR1) in deciduas of unexplained early spontaneous abortion. Methods: 37 women with unexplained spontaneous abortion at 6~10 weeks of gestational period servedas abortion group.

目的:检测蜕膜组织肿瘤坏死因子受体1(Tumor necrosis factor receptor, TNFR1)的表达含量及其组织学、细胞学定位,探讨不明原因早期自然流产与患者TNFR1基因表达的关系。

In the pregnant group, p38MAPKpositive expression was weak at 3 days and peaked at 4 to 5 days in the endometrium of pregnant mice, then declined in the lumina epithelium, but increased in decidual cells.

d呈强阳性表达,此后腔上皮表达逐渐减弱;腺上皮p38MAPK的表达一直维持在阳性水平,而蜕膜细胞的表达从孕5d开始逐渐增强。

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