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The results suggest that Ca 2+ CaM system might be directly involved in the development and maintenance of uterine decidua and play an important role in it.

由此推测,Ca2+-钙调素系统可能直接参与子宫蜕膜的发育和维持,并在其中发挥重要作用。

There was a high level of PGT expression inthe primary decidual zone on days 6 to 8 of pregnancy and in artificially induced decidua.

在妊娠第6-8天蜕膜或人工诱导的蜕膜组织中,PGT mRNA和蛋白在初级蜕膜区有高水平表达。

Methods: Expression levels of MMP10 gene and protein in human spontaneous abortion decidua were determined by RT-PCR, Western blotting and distribution by immunohistochemistry.

利用RT-PCR和Western blotting技术分别检测MMP10基因和蛋白在人正常蜕膜和自然流产蜕膜的表达水平、利用免疫组织化学技术检测MMP10在人正常蜕膜和自然流产蜕膜组织中的分布。

Decidual tissue is a very complex and highly concordant tiny environment between mother and embryo during pregnancy, which is constituted of the variety cells such as extravi11ous trophoblast,endometrium cells, bone marrow cells, decidua l microphage,T cells and a few B cells and so on.

正常蜕膜组织是母-胎界面间一个非常复杂而又高度协调的微环境,它由多种细胞如侵袭至蜕膜的绒毛外滋养细胞(extravi11ous trophoblast,EVT)、子宫内膜源性细胞(如上皮细胞和血管内皮细胞)、骨髓源性细胞(如大颗粒淋巴细胞、蜕膜巨噬细胞、T细胞和少许B细胞)构成,这些细胞以及由这些细胞、母体和胎儿所分泌到蜕膜的细胞因子共同形成了母-胎间信息交流的平台,并对胚胎滋养细胞"有控性"侵袭、子宫内膜的免疫容受性、蜕膜化和胎盘的形成进行精细的调控。

Results: IL-8 protein was located in the epithelium of viii. The expression of IL-8 was significantly increased in RSA group than that in the control group. Positive IL-8 cells was shown in decidua of RSA group, and its IL-8 level was higher than that in the control group. By hematoxylin-eosin staining. trophoblastic layer was found to get thinner, cells of trophoblastic layer denatured or necrotized, and turned acidophily, and the fibration of villous axis increased in RSA; decidual cells lost connection, a part of decidual cells appeared cytoclasis and turned more acidophilic, and nuclei disappeared in RSA.

结果:在绒毛组织中,IL-8蛋白定位于绒毛上皮细胞的细胞质内,且病例组的表达明显高于对照组;在蜕膜组织中;病例组蜕膜细胞的胞质内可见IL-8蛋白表达,且高于对照组;H-E染色可见病例组绒毛组织的滋养层变薄,细胞变性甚至坏死、嗜酸性增强,绒毛中轴纤维化程度增强;蜕膜组织中蜕膜细胞失去细胞间连接,部分蜕膜细胞解体、核消失。

A strong level of caveolin-1 expression was observed in the decidualized cells and vascular endothelial cells at mesometrium side from days 6 to 8 of pregnancy.

小窝蛋白-1在妊娠第5天的基质中以及第6-8天的子宫次级蜕膜区有较强的表达,特别是在第6-8天系膜侧的次级蜕膜区的蜕膜基质细胞及血管内皮细胞中表达很强。

Under artificial decidualization, caveolin-1 mRNA and immunostaining were mainly seen in the decidualized cells and vascular endothelial cells at the mesometrium side.

在人工诱导蜕膜化的子宫内膜中,小窝蛋白-1 mRNA和蛋白主要在近肌层和系膜侧次级蜕膜区表达,并且在系膜侧次级蜕膜区血管内皮细胞中也有较强的表达。

On day 8 of pregnancy, STAT3 immunostaining was mainly located in the decidual area near the lumen, and tyrosine-phosphorylated STAT3 immunostaining was seen in the decidual area near the myometrium, being stronger in the mesometrium side.

妊娠第8天时,STAT3免疫染色主要位于近腔蜕膜区,而酪氨酸磷酸化的STAT3主要位于近肌层蜕膜区,在子宫系膜侧的蜕膜中酪氨酸磷酸化STAT3的信号较强。

We have demonstrated that the expression of protein kinase Cisoform are associated with the development of deciduomata in the pseudopregnant and pregnant rats.

我们过去的研究中已经发现,在蜕膜的形成过程中,不论是在真怀孕或假怀孕大鼠蛋白激酵素C异构体都参与其中蜕膜的形成,因此我们猜测PKC可能参与调节蜕膜细胞的增殖。

The mechanism of mifepristone for termination of early pregnancy might be related to the down-regu- lated expression of OPN and up-regulated expression of p53 protein in the chorion and deciduas.

米非司酮终止早孕的机制可能与绒毛及蜕膜的OPN表达下调,p53蛋白表达上调有关。

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