蜕膜

Methods: Separate and abstract the effective components of Huangqi (Omni-Saponin、total-flavone) and Danshen (Danshen-ketone、 Danshen-Quinone). Applying L-Arginine methyl ester to pregnant rats by I. P to make Nitrogen Oxide Synthesis blocking models (uterus-placenta-fetus lacking blood and oxygen model or pregnant hypertension syndrome model). On day 12, 18 of pregnancy paunched the rats and took out the fetus and placenta/uterus. Measured the basal BP during pregnant period and BP、protein、basal activity each day. Observed placenta/deciduas ultramicroscopic structure by electron microscope and took count of languishment cells. Measured the expressive intensity of bcl-2、Bax of placental nutrient cells by SABC method.

一氧化氮合成酶阻滞剂L-精氨酸甲酯妊娠大鼠腹腔给药，制作一氧化氮合成阻滞模型（子宫-胎盘-胎儿缺血缺氧或妊娠高血压模型），妊娠第12、18天剖腹取胎、胎盘／子宫，妊娠期测基础血压，每日测血压、蛋白质量、基本生理活动；电镜观察胎盘／蜕膜超微形态结构，并进行细胞凋亡计数；免疫组化检测胎盘滋养细胞bcl-2、Bax表达强度；原位杂交法检测胎盘滋养细胞、血管内皮细胞VEGF、eNOS、iNOS、MCP-1、MMP9（基质金属蛋白酶9）mRNA表达。

The extensive involvement of the peritoneal cavity and the presence of ascites militate against the diagnosis of deciduosis.

广泛的腹腔累犯和存在腹水，不支持蜕膜病的诊断。

In the deciduas of spontaneous abortion model group, IL-4, IL-10 cytokine content is clearly lower than that of the traditional Chinese medicine bundle and normal pregnancy group.

自然流产模型组蜕膜中IL-12、IFN-γ含量明显高于中药组及正常妊娠组，与中药组比较有显著性差异（p＜0.05），与正常妊娠模型组比较，有高度显著性差异（p＜0.01）。

After the establishmen of implantation,endometrial stromal cells begin to undergo decidualization for the subsequent embryo development and placentation.

在啮齿类动物，着床过程启动后，子宫内膜基质细胞发生广泛的蜕膜化，为接下来的胚胎及胎盘发育做准备。

MMP25 may play an important role in embryo implantation and placentation.

蜕膜组织中MMP25主要在腺上皮细胞表达，自然流产组的表达微弱，两组平均光密度分别为0.25±0.13和0.21±0.12，差异有统计学意义(P＜0.05)。

On day 10.5, trophoblast giant cell expressed both TIMP-1 and TIMP-3 mRNA, which may be consistent with their functional switch. So it is reasonable to suggest that MMP-2, TIMP-1 and TIMP-3 play an important role in the process of mouse placentation.

所以，MMPs和TIMPs在小鼠滋养层细胞和子宫蜕膜中的协同表达表明其在着床过程中可能发挥重要作用。

Both caveolin-1 mRNA and immunostaining were observed in the stroma on days 4 and 5 of pseudopregnancy.

这说明小窝蛋白-1在子宫基质细胞蜕膜化的和血管发生的过程中可能起重要作用。

There was a low level of PPAR5 mRNA expression in the luminalepithelium and the glandular epithelium from day l to 8 of pseudopregnancy.

在妊娠第6-9天子宫蜕膜中，PPARδmRNA和蛋白均有较强表达。

The aim of this study was to investigate the differential expression of mPGES-1 in rat uterus during early pregnancy, pseudopregnancy, delayed implantation and activation, artificial decidualization and inhibitor treatment by in situ hybridization and immunohistochemistry.

本实验利用原位杂交和免疫组化方法，检测了早期妊娠、假孕、延迟着床、人工诱导蜕膜化以及抑制剂处理等条件对大鼠子宫中mPGES-1表达的调节。

The aim of this project was to study basigin expression in rat uterus during early pregnancy and estrus cycle, and its regulation under pseudopregnancy, delayed implantation, artificial decidualization and steroid treatment by in situ hybridization and immunohistochemistry.

本实验以大鼠为材料，利用原位杂交和免疫组化方法检测了basigin基因在大鼠早期妊娠、发情周期子宫中的表达；并利用假孕、延迟着床、人工蜕膜化及卵巢切除等模型研究basigin基因在大鼠子宫中的表达与调节。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。