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Objective: Construct of cDNA expression library of Human decidua and Screen the antigen about the embryo development.

目的:构建人蜕膜组织的cDNA表达文库,筛选蜕膜组织中与胚胎发生有关的抗原。

ResultsThe expression of STAT 4、STAT 6 were both positive and located mainly in the decidua cells.

结果① 对照组和URSA组蜕膜组织中STAT 4、STAT 6均呈阳性表达,阳性染色主要位于蜕膜细胞的胞浆,胞核多数无明显着色。

Under artificial decidualization, cPLA2α mRNA signal and immunostaining were mainly seen in the decidualized cells at the mesometrium side.cPLA2α immunostaining was observed in luminal and glandular epithelium of mouse uterus on days 1, 4, 5 and 8 of pseudopregnancy.

在人工诱导蜕膜化的子宫中,cPLA2α蛋白和mRNA主要在系膜侧的次级蜕膜区表达。

Through upregulating the production of MMPs in deciduas and chorionic villi, the upregulation of the expression of EMMPRIN in syncytiotrophoblast and cytotrophoblast column of the villi in the threatened abortion can degenerate deciduas and denudates embryo.

发生先兆流产时合体滋养细胞、细胞滋养层柱所表达的EMMPRIN增强可能通过上调绒毛及蜕膜组织中基质金属蛋白酶的水平,降解细胞外基质,使绒毛剥离、蜕膜组织剥脱。

The results showed that the expression of PKCα was observed in both endometrial and decidual tissues by immunohistochemical staining.

在子宫蜕膜中PKCα主要位於蜕膜细胞的细胞膜上,然而在子宫内膜的细胞膜上却仅有少量染色的发现。

This study aimed to establish a culture method for DSC in mouse uterus. The construction of a co-cultured system of decidual cells will lay a good foundation to study pathological pregnancy.

实验拟建立良好的小鼠子宫蜕膜基质细胞培养方法,为进一步建立蜕膜细胞共培养系统将为研究病理性妊娠打下良好的基础。

The HBsAg was located in the intervillous space (21 placentas) and...

HBsAg主要分布于蜕膜血管内皮细胞(18例)、蜕膜细胞(21例)、滋养层细胞(8例)、绒毛间质细胞(8例)和绒毛血管内皮细胞(5例)的胞浆和绒毛间隙(21例)中。

HBV transplacental transmission route may be realized by cell to cell transfer in placenta, which means that HBVs in maternal blood and/or intervillous space infect DCEC and/or DC and/or TC, then transmit to VMC, then to VCEC, and finally to fetus.

HBV经胎盘感染胎儿的路径可能是通过胎盘细胞至细胞的传递而实现的。即母血和/或绒毛间隙HBV→蜕膜毛细胞管内皮细胞和/或蜕膜细胞和/或滋养层细胞→绒毛间质细胞→绒毛毛细血管内皮细胞→胎儿。

CPLA2α mRNA and immunostaining were located in decidualized cells in the mesometrium side from days 6 to 8 of pregnancy.

在妊娠第6天系膜侧的初级蜕膜区,以及第7~8天的系膜侧的次级蜕膜区,可以检测到cPLA2α蛋白和mRNA的表达。

Results: The mRNA expression of VEGF and its reccptors, KDR and flt-1, was significantly higher in the tubal pregnant decidual tissue compared with the normal oviductal tissue, but lower than that in the early pregnant human endometrial decidual tissue.

结果:半定量结果表明,VEGF、KDR、Flt-1 mRNA在输卵管妊娠蜕膜组织中的表达强于正常输卵管组织,但弱于正常宫内早孕蜕膜组织,差异均有显著性。

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