蛋白黑素

There are many complex and unique aspects of melanocortin signaling, such as the existence of endogenous antagonists, the agouti proteins, that act at three of the five melanocortin receptors.

点，比如内源性拮抗剂的存在，豚鼠蛋白充当了5个黑皮质素受体中的3个。然而，有一种黑色

There are many complex and unique aspects of melanocortin signaling, such as the existence of endogenous antagonists, the agouti proteins, that act at three of the fie melanocortin receptors.

点，比如内源性拮抗剂的存在，豚鼠蛋白充当了5个黑皮质素受体中的3个。然而，有一种黑色

RESULTSdiabetic rats showed typical symptoms involving elevated serum glucose and weight loss (2)The rats in DM+VaD group reacted slower and made more error numbers in Y-maze than the rats in VaD group did, with a prolonged total reacting time in a whole day.(3)More neurons with serious damages, such as edema, ischemia or pyknosis could be found in DM+VaD group than in VaD group. More disarrangement of cone neurons, obvious glia proliferation, and more neuron apoptosis were found in CA area of hippocampus. CONCLUSIONS (1)2-VO in STZ-induced diabetic rats succeeded in establishing VaD animal models.(2) The cognitive dysfunction induced by VaD rats had been deteriorated by diabetes mellitus.(3)Morphology evidences proved that diabetes mellitus aggravated brain damages induced by VaD.PART II Effect of diabetes mellitus on the cholinergic nervous systemin CA1 area of hippocampus of VaDOBJECTIVE To estimate the role of cholinergic nervous system in hippocampus during the process of cognitive dysfunction aggravated by diabetes mellitus in DM+VaD group. METHODS Observe the changes of ChAT protein by immunohistochemistry stain. Chose three rats randomly from each group at each pointat two week, four week, and eight week, then sepa

经腹腔注射链脲佐菌素诱导慢性实验性糖尿病，1周后永久性结扎双侧颈总动脉(2-VO)制作VaD模型记录术后2周、4周和8周各组大鼠的体重及血糖；应用Y-迷宫检测空间定向学第二军医大学博士论文中…丈摘…要1ia；一色恤~﹁染澎糕行HE染色观察组织病理学孪叱；胶质细胞原纤维酸性蛋白protellZ，Cf冰尸标记观察星形胶质细舱的激活情况、橄声软公点娜育票票众糯黑橄居端粗默孺篇筑价井袱第二部分糖尿病对血管性痴呆大鼠海马c心区胆碱能神经系统的影响探讨海马CAI区胆碱能神经系统在糖尿病加重确D一大鼠认知障碍中所实验动物及分组同第一部分，应用免疫组织化学染色方法现察海马CAI{介狱牛第晕军l袭拔常博粗{论义

Objective: To investigate the expression of melanoma inhibitory protein in mammary buds of transgenic mice.

目的：检测黑素瘤抑制蛋白在小鼠胚胎乳腺组织中的表达。

Methods The expression of COX-2 was determined by immunohistochemistry in 45 cases of malignant melanoma and 25 intradermal nevi.

方法免疫组化法比较性研究25例皮内痣、45例恶性黑素瘤COX-2蛋白的表达情况。

The foamy substances cover foam protein, polypeptide, isohumulone, melanoid, metal ions, amylase, alcohol and barm etc.

使啤酒形成泡沫的物质有泡沫蛋白和多肽、异律草酮、类黑素、金属离子、多糖、酒精、二氧化碳及酵母等。

Objective To evaluate the effects of 308 nm monochromatic excimer light on cell apoptosis, cycle of and KIT expression in human melanocytes. Methods Melanocytes were obtained from circumcised prepuce, and subjected to primary culture.

目的 探讨308 nm单频准分子光对体外培养的人黑素细胞凋亡、细胞周期和KIT蛋白表达的影响。

Its protein product was found to also suppress metastasis of melanoma cells and murine mammary carcinoma cells.

它所编码的蛋白还可以抑制黑素瘤细胞和小鼠乳腺癌细胞的转移。

Methods Huma n brain glioma cell lines, GBM and BT325 were incubated in the medium containing 59Fe-Citrate.

目的 探讨黑素转铁蛋白p97在人脑胶质瘤细胞铁摄取中的作用。

Here we report frequent somatic mutations in the heterotrimeric G protein alpha-subunit, GNAQ, in blue naevi (83%) and ocular melanoma of the uvea (46%).

我们在此报道了蓝痣(83%)和眼葡萄膜黑素瘤(46%)中异源三聚体G蛋白α亚单位——GNAQ——的屡次突变。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐