蛋白酶

Objective To explore the significance of expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases -2(TIMP-2) in benign and malignant hydatidiform molr.

目的 探讨基质金属蛋白酶(MMP- 2 )及金属蛋白酶组织抑制因子(TIMP- 2 )在良、恶性葡萄胎组织中的表达及临床意义。

Objective The aim of this study was to evaluate the reaction of the rat－ lung to elastase by a single intratracheal instillation of elastase.

目的在 SD大鼠气管内滴入猪胰弹性蛋白酶，复制肺气肿模型，观察鼠肺对弹性蛋白酶的反应。

Except for control group, rats in the other groups were intratracheally administered with bleomycin. Animals in pulmonary fibrosis model groups were sacrificed on day 3, 7, 14, 28 and 56. The sections of the right lung were stained by HE, Masson and sirius red. The left lung was weighed and its hydroxyproline content was assayed. The mRNAs of TGF-β1, MMP-9 and TIMP-1 in the lung homogenate were measured by semi-quantitative RT-PCR.

除N组外，其余各组采用气管内注入BLM致大鼠肺纤维化模型，分别于3、7、14、28、56d处死各组大鼠，右肺行苏木精－依红、Masson胶原及天狼猩红染色，测定左肺经脯氨酸的含量RT-PCR法半定量测定转化生长因子－1(TGF-β1)、基质金属蛋白酶－9(MMP-9)和基质金属蛋白酶组织抑制物－1(nMP-1)mRNA在肺内的表达。

Objective To investigate the relationship between serum level of matrix metalloproteases-9 (MMP-9), tissue inhibitors of matris metalloproteinase-1 (TIMP-1) and coronary atherosclerotic plaque rupture, and the correlations between MMP-9,TIMP-1 and the degrees of coronary artery lesion .

目的 探讨血清基质金属蛋白酶(MMP-9)及基质金属蛋白酶抑制因子-1(TIMP-1)与动脉粥样硬化斑块破裂关系，分析MMP-9及TIMP-1与冠脉病变程度的相关性，进一步了解MMP-9及TIMP-1在冠脉粥样硬化发生发展中的作用及临床意义。

The MEROPS database provides a catalogue and structure-based classification of proteases (termed "peptidases" within the database), together with a wealth of additional information about them.

MEROPS是蛋白酶数据库。它提供蛋白酶的目录和基于结构的分类以及一些它们的附加信息。

The process of osteoarthritis mesochondrium degradation is possibly attributed to the synergistical consequence of MMPs and other factors. Pilose antler peptide can promote the proliferation of OA chondrocytes of rabbits ,inhibit the overexpression of MMPs of OA chondrocytes.It can possibly play a effective role in the treatment of OA.

结论骨性关节炎软骨细胞在骨性关节炎发病过程中，软骨细胞正常分化及增殖发生改变；骨性关节炎软骨基质降解过程可能是金属蛋白酶与其它因子协同作用的结果；鹿茸多肽可促进骨性关节炎软骨细胞增殖，并可抑制骨性关节炎软骨细胞中金属蛋白酶的过度表达，可能对治疗骨性关节炎有较好的作用。

This review focused on the biological significance of matrix metalloproteinases in its regulation when mesenchymal stem cells differentiate into myoblastic, osteoblastic, chondroblastic, neural, and apidoblastic lineages.

文章详细阐述了基质金属蛋白酶在间充质干细胞分化为成肌细胞、成骨细胞、破骨细胞、神经细胞、脂肪细胞过程中所起的重要生物学作用，并对基质金属蛋白酶在间充质干细胞分化中的调控作用进行分析。

In nonclinical studies, normal cells appear to beable to recover from intermittent proteasome inhibition, but many types of cancercells undergo apoptosis when proteasomes are inhibited, even for a short time.

它可以选择性地抑制蛋白酶小体的苏氨酸蛋白酶活性，减少对特定细胞周期调节蛋白(IkB、p53、p27、p21等)的降解。由于这些调节蛋白的集聚，肿瘤细胞分裂周期受到干扰，细胞分裂停止，最终导致细胞凋亡。

Periploca sepium Bunge;protease;trypsin-like;chymotrypsin-like;lipase;amylase

杠柳；蛋白酶；类胰蛋白酶；类胰凝乳蛋白酶；脂肪酶；淀粉酶

The number of proteinase inhibitor genes required to protect the pathogens from plant proteases is also expanded in the Phytophthora genomes.

有多少蛋白酶抑制剂基因要求，以保护病原体从植物蛋白酶，也扩大了在疫霉基因组中。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。