蛋白质

Protein tyrosine phosphtases are a superfamily of structurally and functionally related enzymes for dephosphorylation of pr...

蛋白质酪氨酸磷酸酶是催化蛋白质去磷酸化的一类庞大的酶家族，在细胞信号传导及代谢的调节中起重要作用。

The extent of inhibition of depolarization by superfusion of ethanol for 5 minutes was 41.8±3.3 ％(n=17). The addition of 5 nM and 20 nM KT5720 (a selective protein kinase A inhibitor) and 250 μM H9 dihydrochloride (a non-selective protein kinase inhibitor), into the intracellular solution significantly attenuated the inhibitory effects of ethanol.

当分别将5 nM或20 nM KT5720（选择性蛋白质激酶A抑制剂）或250 μM H9 dihydrochoride（非选择性蛋白质激酶抑制剂）置入细胞内液时，乙醇的抑制作用明显被减弱；但乙醇的抑制作用不受到5 nM或20 nM calyculin A（磷酸酶1/2A抑制剂）的影响。

The regulation of gene expression is to have relations to the assembly of the DNA binding proteins which bind to DNA to initiate the transcription. Some of these proteins have the ability to promote bending or looping of DNA. The FIS protein regulates gene expression in Escherichia coli by this property of bending DNA. There are many researches to discover the mechanism of FIS protein binds to DNA. However the experiment data only show the supposititious results and figure out the model of FIS-DNA complex structure. This research uses molecular dynamics simulation to compute the detail of the interaction between FIS and DNA. We observed FIS prominently affects the DNA bending by the type of local bending. Analyzing the DNA structure properties, roll and slide, also demonstrates the local bending type and region. The hydrogen bonds between FIS and DNA are analyzed to compare with the experiment data. Finally we compute the binding free energy between FIS and DNA to estimate the result of simulation and compare with the value of λ-repressor-DNA complex.

基因的表现与结合於DNA促使DNA转录作用起始的DNA结合蛋白组装有关，一些这类的蛋白质具有促使DNA扭曲或将DNA形成环状的能力，FIS蛋白质即是藉由扭曲DNA的特性调控大肠杆菌基因的表现，目前已有很多的研究发现FIS与DNA结合的机转，然而这些实验的数据仅能显示推测性的结果，进而利用这些结果推论出FIS与DNA聚合体结构的模型，本研究利用分子动态模拟的方式计算FIS与DNA交互作用的细节，我们观察到FIS主要影响DNA的扭曲方式为DNA区域扭曲的类型，并且分析DNA结构特性roll与slide也指出扭曲方式为区域扭曲与其扭曲的区域，我们也分析FIS与DNA之间的氢键，并且与实验的资料作比较，最后我们计算FIS与DNA之间的结合自由能评估模拟的结果，并且计算出的值和λ-repressor与DNA聚合体结构的实验值作比较。

Many studies have shown that the protein " surface " structure , the function of the protein has a decisive influence on ...

许多的研究显示出，蛋白质的「表面」结构，对蛋白质的功能有著决定性的影响，。。。

Heat and pH stability of the protein make it an ideal system for investigating the chemical and structural requirements of a sweet-tasting protein.

热和酸碱度稳定蛋白质做它一个理想的系统为调查化工和结构要求sweet-tasting 蛋白质。

Aminoacyl-tRNA synthetase is a class of ancient proteins, catalyzing the first reaction of protein biosynthesis.

氨基酰-tRNA合成酶是一类古老的蛋白质，催化蛋白质生物合成中的第一步反应。

At the web-based control page, it is able to upload our 2-D PAGE data and download the Tag Image File Format image. The 2-D PAGE data can be searched easily by limitation such as Peptide, NCBI Accession number, Map, Organisms, pI/Mw range, Drug/Compound, and Operator.

在这个网路管理介面内，我们可上传二维聚丙烯醯胺胶体的电泳资料、下载标志图形档案格式的影像图片，并且我们可以很容易的藉由如：蛋白质的名称、NCBI的登录号码、图像、胶片所使用的物种、蛋白质的等电点值与分子量范围（pI/Mw range）、胶片使用的抗生素或化合物（Drug/Compound）以及实验操作者等条件来搜寻二维聚丙烯醯胺胶体电泳资讯。

Japonicum, covering 90% of its total genes; find 8400 protein-coding genes; set up the largest functional gene database and clone libraries in the world; for the first time, identify as many as 3260 proteins from variety of life stages of S. japonicum; analyse the eggshell proteins and tegument proteins, which were the putative targets for drugs and candidates of vaccines; reveal a large quantity of genetic polymorphisms in the genes of S.

对人CD34+造血干／祖细胞进行了转录组和蛋白质组学研究，鉴定了370个蛋白质，这是迄今为止鉴定最多的CD34+细胞蛋白，并且鉴定了各种转录组研究没能发现的133个CD34+细胞蛋白，发现了CD34+细胞具有可塑性的新的证据，证明了反义核酸未能完全阻止其相应基因的表达，并提出一些蛋白的异质性是由于翻译后修饰造成；2。

Virus hasn't cell construction. A lot of simple virus is only made of nucleus acid and protein tegument, so we can regard it as nucleoprotein. A type of virus pill usual has a kind of nucleus acid. After virus infect sensitive host cell, the nucleus acid of virus will enter cell and produce its descendant and new protein by reproduction and expression. Then, the new synthetic virus is made up of descendant that release form cell by regular way. This specific way of reproduction of virus called reproduction.

病毒不具有细胞结构，一些简单的病毒又由核酸和蛋白质构成，故可把它们视为核酸蛋白分子，一种病毒的毒粒内通常只含有一种核酸，病毒感染敏感宿主细胞后，病毒核酸进入细胞，通过其复制与表达产生子代病毒基因组和新的蛋白质，然后由这些新合成的病毒组分装配成子代毒粒，并以一定的方式释放到细胞外，病毒的这种特殊繁殖方式称为复制。

The major muscle protei , actin and myosin, convert chemical energy to mechanical work, while protei in tendo bind muscles to bones, skin, hairy fingernails, and toenails are pertinacious protective su tance.

重要的肌肉蛋白—肌动蛋白和肌球蛋白把化学能转变成机械能；而腱中的蛋白质则是将肌肉粘连在骨骼上。皮肤、毛发、指甲是蛋白质类的保护物质。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。