蛋白的

Results The expression of the Mahoganoid protein and its mRNA was showed by brown staining and observed in the Leydig cells, spermatogonia, primary spermatocytes, spermatids, Sertoli cells, and peritubular myoid cells of testicular tissues and principal cells, basic cells and epithelial cells of epididymal tissues.

结果1。免疫组化法检测Mahoganoid蛋白的实验结果显示的棕色阳性信号可见于各天龄段大鼠睾丸的生精细胞、支持细胞、间质细胞和管周肌样细胞以及附睾输出管的高柱状、低柱状上皮细胞和附睾管的上皮细胞、主细胞、基细胞。其中Mahoganoid蛋白主要表达于胞膜和胞浆。

These ES cells were introduced into host embryos from outbred KMW though blastocyst injection. Using GFP, the attractive genetic marker, we have been able to follow the fate of ES cells in living embryos and to observe directly the contribution of these cells to mouse embryos. Totally, four GFP-expressing 'green' chimeric mice expressing GFP were obtained.

为研究嵌合体动物中供体胚胎干细胞在宿主胚胎发育中的走向和定位，同时探讨绿色荧光蛋白基因作为报告基因在转基因动物制作中的应用价值，本研究将pEGFP-N1基因导入小鼠ES-D3细胞系，得到稳定表达GFP的胚胎干细胞亚系ES-D3-GFP，通过对昆明小鼠的囊胚腔注射，获得了4只表达绿色荧光蛋白的嵌合体小鼠。

When Shigella flexneri 2a 2457T is cultured at 30℃, it's phenotypically avirulent; when grown at 37℃, its virulence improves greately. There is clear evidence that the temperature-dependent expression of the virulence genes is controlled by H-NS protein.

痢疾杆菌在30℃时不具有侵袭力，37℃时毒力明显增强，已有的研究表明这种依赖于温度的毒力基因的表达受H-NS蛋白的调控。H-NS是一种重要的类核相关蛋白，在革兰氏阴性菌中普遍存在，能够调控大量基因的表达。

Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey 08854, USA3 Correspondence to: Charalampos G. Kalodimos1,2 Correspondence and requests for materials should be addressed to C.G.K.

一项新的研究表明，认为变构蛋白的活性纯粹由结构调控的观点应当予以修正，将来自蛋白动态的一个经常占支配地位的贡献包括进去。

Inhibition of PKCdelta by rottlerin or knockdown of TG2 protein by a TG2-specific siRNA resulted in a marked increase in autophagy shown by presence of autophagic vacuoles in the cytoplasm, formation of the acidic vesicular organelles, membrane association of microtubule-associated protein 1 light chain 3 (LC3) with autophagosomes, and a marked induction of LC3-II protein, important hallmarks of autophagy, and by electron microscopy.

抑制PKCdelta的rottlerin或击倒的TG2蛋白质的TG2特定的siRNA导致显着增加，表明自噬存在自泡在细胞质，形成酸性囊泡细胞，膜协会微管相关蛋白1轻链3（ LC3 ）与autophagosomes ，并显着诱导LC3 -Ⅱ蛋白的重要标志吞噬，并通过电子显微镜。

Coli pET32/IL-11/BL(DE21 that expressed recombinant human interleukin-11 in the flask have been studied by orthogonal experiment design, including the components of culture medium (glucose, tryptone, yeast extract and pH), shaking speed, medium volume and inoculum concentration.

为了探讨发酵条件对大肠杆菌表达人白细胞介素-11融合蛋白的影响，利用正交实验设计，对影响工程菌的生长及重组人白细胞介素11融合蛋白的表达因素如培养基中的葡萄糖浓度、蛋白胨浓度、酵母提取物浓度、无机盐浓度、pH及摇床转速、装液量、接种量等在摇瓶中进行了初步的研究。

Expanding on our demonstration that acylated peptides derived from the large HBV envelope protein block virus entry in vitro, we show their applicability to prevent HBV or woolly monkey hepatitis B virus infection in vivo, using immunodeficient urokinase-type plasminogen activator mice repopulated with primary human or Tupaia belangeri hepatocytes.

已有的研究《Hepatitis B virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans》（2007 Hepatology）表明来源于大蛋白的酰化多肽在体外能阻断病毒的进入。利用人源化肝脏或树鼩肝细胞的小鼠模型进行的新研究进一步证实，大蛋白的酰化多肽在防止HBV或者绒毛猴HBV体内感染中具有可行性。

The high-resolution crystal structure of TIPE2 reveals a previously uncharacterized fold that is different from the predicted fold of a death effector domain.

清华大学施一公的研究小组对TIPE2的晶体结构进行了分析，发现其真实的蛋白折叠结构与先前用软件预测的折叠结构有出入，尤其是该蛋白的死亡效应区域结构。

At the same time, the change of the fluorescence and the activity was detected when the enzyme was thermally denatured.

结果表明，该酶的稳定性非常好，蛋白的质量浓度为0.4 mg/mL时， 90 ℃的半衰期为20 h， 0.2 mg/mL时的半衰期为12 h；而蛋白的质量浓度为0.04 mg/mL时，保温2.5 h时残余活力仍在50%以上。

In this investigation, TP could inhibit the ATPase's activity of P-gp in dose-dependent manner, indicating that TP exerted their modulation effect on MDR through inhibiting the ATPase activity of P-gp, and consequently interdicting the pumping function of P-gp on anti-cancer drug.

研究发现TP剂量依赖性的抑制ATPase活性，说明TP可以通过抑制P-gp糖蛋白的ATP酶活性的方式阻断P-gp糖蛋白对抗癌药物的溢出作用从而发挥其逆转MDR的作用。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。