蛋白核

High mobility group protein; enhanceosome ; nucleosome ; regulation of gene expression

高迁移率族蛋白；增强体；核小体；基因表达调控

And we get the nucleosome structure. DNA wraps around histone about 2 loops.

在适当的参数条件下，得到了合理的结果，即DNA能够缠绕组蛋白约两圈形成准核小体结构。

The histone, nucleosome and DNA models were derived from their PDB ( http://www.rcsb.org/pdb/) structures and other published data.

组蛋白、核小体和DNA分子的结构，源自它们在PDB等公开资料中的数据。

These modifications regulate histone-DNA interactions, adding a new dimension to the epigenetic regulation of nucleosome mobility.

这些修饰调控组蛋白-DNA相互作用，为核小体迁移率的表观调控添加了新的内容。

Objective The aim of this study was to investigate the expression of NF-κB and the re-expression of α-and β-catenin in cancer cells of metastatic lymph nodes in advanced gastric carcinoma.

目的 探讨进展期胃癌核因子κB(nuclear factor kappa B， NF-κB)蛋白的表达与α-catenin及β-catenin在转移淋巴结内癌细胞中的再表达情况及其与临床病理因素的关系。

Aromatase protein and its mRNA were abundant in the forebrain, midbrain, spinal cord, wheel organ and Hatschek's pit, but not abundant in the hindbrain or early ovary and testis. No aromatase expression was detected in both irregularshaped cells and ciliated mucous cells in the Hatschek's pit or in the mature ovary and testis. Aromatase immunoreactive material was distributed in the cytoplasm with negative nuclei.

芳香化酶蛋白和转录物在前脑、中脑、脊髓、轮器和哈氏窝十分丰富，而后脑、早期卵巢和精巢不够丰富；没有芳香化酶表达的部位是哈氏窝另两种细胞(不规则形细胞和带纤毛粘液细胞)以及成熟卵巢和精巢；芳香化酶免疫活性物质分布在胞质，核为阴性。

Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, suppressing expression of integrin expression in cultured glomerular epithelial cells.

氨基核苷嘌呤霉素诱导肾病变是人原发性肾病综合症的模型，抑制培养的肾小球上皮细胞整联蛋白的表达。

The mice in experimental group and control group were exposed to 350 cGy radiation produced by 60Co. After 3 h, karyocytes at different concentrations in the fresh human umbilical cord blood were injected into the mice in experimental group A, B, C via their tail veins, and the equal volume of normal sodium was also injected into control group via tail veins. After one month, carbon tetrachloride (CCl4) was injected into experimental group A, B and control group via abdominal cavity, and the equal volume of normal sodium was injected into experimental group C. After two months, immunohistochemistry and reverse transcriptase polymerase chain reaction were used to detect the expressions of human cytokeratin-18 (CK18), cytokeratin-19 (CK19) and albumin in liver tissues of all mice.

采用60Co治疗仪γ射线对实验组和对照组行350cGy的亚致死剂量照射，实验组A、B、C3组照射后3h内经尾静脉分别输入1.0×10^7个/只、2.0×10^7个/只和3.0×l0^7个/只人新鲜脐血有核细胞，对照组经尾静脉注入等体积无菌生理盐水。1个月后对实验A、B组和对照组裸鼠经腹膜腔注射四氯化碳(CCl4)，实验C组注射等体积生理盐水。2个月后采用免疫组化和RT-PCR方法检测裸鼠肝组织人源性CK18、CK19和人源性白蛋白的表达。

We determined the nucleoporin 85 (Nup85) Seh1 structure, a module in the heptameric Nup84 complex, at 3.5 angstroms resolution.

研究人员以3.5埃的分辨率确定了七聚Nup84复合体的一个组件，核孔蛋白85 (Nup85) Seh1的结构。

And 98. 3% respectively Conclusions To all the eleven antinuclear autoantibodies , the sensitivity is all above 95.0% and specificity is all above 98.0%, which indicate that there is high concordances between the ANAs protein chip and the methods used in clinical screening and confirmation, and it could meet the requirement of clinical autoantibodies profile detection.

结论蛋白芯片技术检测11种抗核抗体谱自身抗体的检测敏感度（均〉95.0％）和特异度（均〉98.0％）均较高，且与IIF和EHSA法有较高的符合率，能满足临床检测自身抗体谱的要求。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐