蛋白样的

The feature of this disease was characteristized by hyper gammaglobulinemia,elevated serum IgG4 levels,the presence of autoantibodies against carbonic anhydrase and lactoferrin,a diffused intumescence on pancreas,prominent lymphocyte infiltration with fibrosis in the pancreas.

此病的特点为高球蛋白，IgG4升高，抗碳酸酐酶抗体和抗乳铁蛋白抗体的存在，弥漫性肿大的胰腺、显著的淋巴细胞浸润伴随纤维化，临床表现多样，经典的腹部CT表现为胰腺弥漫性肿大呈腊肠样，密度均匀，轻微强化，周边低密度囊状缘，对激素治疗敏感。

NG108-15 cells was first incubated for a day in CO2 incubator with Dulbecco-improved Eagle medium of 0.1 molarity at 37 ℃, then 5 μmol/L amyloid protein 25-35 segment or 200 nmol/L segment 1-42 was added to continuously incubate for a day, after that the cell models of Alzheimer disease was ready.

NG108-15细胞以Dulbecco改良的Eagle培养基在37℃，体积分数为0.1的CO2培养箱中培养1d，然后加入浓度为5μmol/L淀粉样蛋白25-35或200nmol/L淀粉样蛋白1-42片段，继续培养1d后，即为老年性痴呆细胞模型。

The team discovered that curcuminoids enhanced the surface binding of amyloid beta to macrophages and that vitamin D strongly stimulated the uptake and absorption of amyloid beta in macrophages in a majority of patients.

研究发现，对于大多数病人，姜黄素类衍生物提高了β淀粉样蛋白与巨噬细胞的表面结合，而维生素D强烈刺激了巨噬细胞内β淀粉样蛋白的摄取和吸收。

In this study, immunohistochemical staining was performed with antibodies against D2-40, S100, pankeratin, epithelial membrane antigen, brachyury, and glial fibrillary acidic protein in 4 cases of chordoid glioma, 6 skeletal myxoid chondrosarcomas, 10 chordoid meningiomas, 16 extraskeletal myxoid chondrosarcoma, 18 chordomas, 22 low-grade chondrosarcomas, and 27 enchondromas.

本研究中，我们给4例脊索样胶质瘤、6例骨的黏液样软骨肉瘤、10脊索样脑膜瘤、16例骨外黏液样软骨肉瘤、18例脊索瘤、22例低级别软骨肉瘤和27例内生性软骨瘤做了D2-40、S100、pankeratin、上皮膜抗原、brachyury和胶质纤维酸性蛋白的免疫组化染色。

Some evidence indicates that the combination of extrinsic, intrinsic and genetic factors all play a role to cause the disc degeneration, with a progressive decrease in proteoglycan content leading to dehydration of the nucleus pulposus, and Type Ⅰ collagen begins to appear in the matrix, the ratio between Type Ⅰ and Type Ⅱ increases. All these cause the swelling pressure, disc height and the disc load bearing ability decrease. The disc progressively herniate and cause radiculopathy and myelopathy.

内因、外因及遗传方面的诸多因素导致椎间盘逐步退变后，其实质就是基质中蛋白多糖的减少，含水量降低，Ⅰ型胶原出现在基质中，Ⅰ、Ⅱ型胶原的比例明显上升，髓核呈纤维样改变，导致椎间盘的膨胀压降低，承重能力下降，椎间高度降低，椎间盘承受的重力不能平均地向各方向传递，致使纤维环疲劳、破裂、髓核突出，造成脊髓或马尾神经受压，引起严重后果。

Objectives In order to investigate how does King's Brain pill work or mechanism of King's Brain pill effective in treating AD clinically, we observed effects of extract of King's Brain on neuronal and vascular lesions induced by Aβ combining with praxiology and neuropathology.

目的 运用现代分子神经病理学和行为学技术，围绕炎症假说、淀粉样蛋白瀑布流假说，以神经元和脑血管为保护目标，着眼于AD的关键病理机制Aβ（β淀粉样蛋白沉积和淀粉样血管病变）及其代谢，开展中药补肾活血化痰复方制剂金思维对损伤的神经元和血管的保护作用机理研究，从而探讨其防治老年性痴呆的机理。

The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation, such as zinc finger 198, 263, 14, 224, zf6, novel protein similar to transcriptional represser CTCF, and kruppel-like zinc finger protein; two members of the ADAMs (a disintegrin and metalloprotease domain) family; two members of integrin family; several proteins involved in the signal transduction, cell-cycle control, chromatin remodeling and transcription repression; and also some proteins of cell skeleton and some with unknown functions.

鉴定出 的蛋白包括多个与转录调控相关的锌指蛋白，如锌指蛋白198、263、14、224、zf6、转录抑制因子cTcF样蛋白、幻肚pple样锌指蛋白等：两个含金属蛋白酶结构域和整合素结合结构域的家族成员ADAM28和ADAM17；两个整合素家族成员pZ整合素和含十个EGF样结构域的整合素；与细胞信号转导通路有关的蛋白；与细胞周期调控有关的蛋白；与染色体重塑和基因转录抑制有关的蛋白；细胞骨架蛋白以及其他功能未明的蛋白等。

In this course, the molecular and biochemical basis of the prion diseases, which include bovine spongiform encephalopathy, Creutzfedt-Jakob disease and kuru will be examined.

在本课程中，我们将分析包括了牛海绵体样脑病，克雅氏症，以及库鲁病的朊蛋白疾病的分子和生化的成病基础。

The exact causes of the illness are not known, but disease progression is highly associated with the build-up of clumped beta amyloid proteins in the brain.

该病的病因尚不清楚，但是病程的发展与脑内β淀粉样蛋白斑块的堆积有密切关系。

Pasinetti noted that it might also be possible to identify a concentration of this compound that confers the beta-amyloid blocking benefit without affecting blood pressure.

Pasinetti指出，将来也可能鉴别出在不影响血压的情况下可以阻断β－淀粉样蛋白产生的复方制剂的药量。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。