蛋白休克

Along with the fluconazole solution density rise,the experimental two kind of strain various glucose density is higher,showe d the glucose consumption are less,takes the logarithmof the medicine de nsity,discovered the logarithm the medicine density and each glucose den sity presents the linear relations;Carries on the analysis comparison to under the fluconazole function two kind of strain linear relations,disc overed the relations of the two strains has the nonuniformity.3 Compare the fluconazole induction reaiatance SC5314 strain and sens itive strain compares,its difference gene expression mainly concentrates in:The code proteinase body and the protein hydroltyic enzyme gene,in the code sugar fat metabolism process is connected the protein gene,the cell cycle correlation gene,the duplication and the translation adjustme nt correlation gene,the stress response correlation gene,the line plast ochondria correlation gene,the cell wall function related gene.4 Candida albicans SC5314 induction resiatance strain was processed b y Xianglian solution,its expression change gene mainly is:Code stress re sponse family protein gene,biomembrane relevant gene,a code proteinase body gene race,code cell cycle related protein gene,duplication and tra nslation adjustment related protein gene.5 The clinical reaiatance strain Candida albicans was processed by Xi anglian solution,its expression change gene mainly is:Codes the hot sho ck protein gene,the serine/threonine protein activating enzyme gene,the proteinase body family gene,the regulation copies and translates the ge ne.

随着氟康唑药液的浓度上升，试验的两种菌株各孔葡萄糖浓度越高，说明葡萄糖消耗越少，经过药物浓度取对数后进行分析，发现取对数后的药物浓度和每孔中葡萄糖浓度者呈现线性关系；对氟康唑作用下的两种菌株的线性关系进行分析比较，发现对两种菌株作用具有不一致性。3氟康唑诱导的耐药SC5314菌株与诱导前的敏感株相比，其差异基因表达主要集中在：编码蛋白酶体及蛋白水解酶的基因，编码糖脂代谢过程中相关蛋白的基因，细胞周期相关基因，转录及翻译调节相关基因，应激反应相关基因，线粒体相关基因，细胞壁功能相关基因。4白念珠菌SC5314诱导耐药株经香莲外洗液作用后，其表达变化的基因主要是：编码应激反应家族蛋白的基因，生物膜相关性基因，编码蛋白酶体基因一族，编码细胞周期相关蛋白基因，转录及翻译调节的相关蛋白基因。5白念珠菌临床耐药菌株经香莲外洗液作用后，其表达变化的基因主要是：编码热休克蛋白基因，丝氨酸/苏氨酸蛋白激酶基因，蛋白酶体家族基因，调控转录及翻译基因。

Results摘要: The incidence rates of renal dysfunction, shock, cardiovascular failure and gastrointestinal hemorrhage, the score of acute physiology and chronic health evaluation Ⅱ and the frequencies of pulse and breath in the severe hypoalbuminemia group were all higher than those in the mild hypoalbuminemia group (P＜0.05 or P＜0.01). The differences of incidence rate of hepatic failure and the scores of Ranson and Balthazar CT between these two groups had no statistical significance (P＞0.05). The incidence rate of infection and the mortality in the severe hypoalbuminemia group were higher than those in the mild hypoalbuminemia group (P＜0.01) in the later stage of SAP.

结果摘要：重度低白蛋白血症组肾功能衰竭、休克、心衰及消化道出血的发生率高于轻度低白蛋白血症组（P＜0.01，肝功能衰竭发生率两组比较无统计学差异；Ranson评分及Balthazar CT评分两组间比较，差异无统计学意义（P＞0.05）；重度低白蛋白血症组的急性生理和慢性健康评价指标Ⅱ（acute physiology and chronic health evaluationⅡ， APACHEⅡ）评分、脉搏和呼吸频率均明显高于轻度低白蛋白血症组（P＜0.05或P＜0.01；重度低白蛋白血症组后期感染发生率及病死率均高于轻度低白蛋白血症组

The differences of incidence rate of hepatic failure and the scores of Ranson and Balthazar CT between these two groups had no statistical significance (P＞0.05). The incidence rate of infection and the mortality in the severe hypoalbuminemia group were higher than those in the mild hypoalbuminemia group (P＜0.01) in the later stage of SAP. Conclusion: Hypoalbuminemia in the early stage can accelerate the deterioration in pathophysiology of SAP.

结果：重度低白蛋白血症组肾功能衰竭、休克、心衰及消化道出血的发生率高于轻度低白蛋白血症组（P＜0.01，肝功能衰竭发生率两组比较无统计学差异；Ranson评分及Balthazar CT评分两组间比较，差异无统计学意义（P＞0.05）；重度低白蛋白血症组的急性生理和慢性健康评价指标Ⅱ（acute physiology and chronic health evaluationⅡ， APACHEⅡ）评分、脉搏和呼吸频率均明显高于轻度低白蛋白血症组（P＜0.05或P＜0.01；重度低白蛋白血症组后期感染发生率及病死率均高于轻度低白蛋白血症组

Results: The incidence rates of renal dysfunction, shock, cardiovascular failure and gastrointestinal hemorrhage, the score of acute physiology and chronic health evaluation Ⅱ and the frequencies of pulse and breath in the severe hypoalbuminemia group were all higher than those in the mild hypoalbuminemia group (P＜0.05 or P＜0.01). The differences of incidence rate of hepatic failure and the scores of Ranson and Balthazar CT between these two groups had no statistical significance (P＞0.05). The incidence rate of infection and the mortality in the severe hypoalbuminemia group were higher than those in the mild hypoalbuminemia group (P＜0.01) in the later stage of SAP.

结果：重度低白蛋白血症组肾功能衰竭、休克、心衰及消化道出血的发生率高于轻度低白蛋白血症组（P＜0.01，肝功能衰竭发生率两组比较无统计学差异；Ranson评分及Balthazar CT评分两组间比较，差异无统计学意义（P＞0.05）；重度低白蛋白血症组的急性生理和慢性健康评价指标Ⅱ（acute physiology and chronic health evaluationⅡ， APACHEⅡ）评分、脉搏和呼吸频率均明显高于轻度低白蛋白血症组（P＜0.05或P＜0.01；重度低白蛋白血症组后期感染发生率及病死率均高于轻度低白蛋白血症组

AG-707 (recombinant heat shock protein 70 polyvalent peptide complex) is a heat shock protein–based vaccine that is designed to activate the immune system to target HSV-2 infection in a broad population of patients.

银707 （重组热休克蛋白70多肽复合物）是一种热休克蛋白为基础的疫苗是专为激活免疫系统的目标，单纯疱疹病毒2型感染，在一个广泛的人口的病人。

Chlamydia infection induced dose-dependent NF-kappaB reporter activity in CHO╱CD14 cells and enhanced by TLR2 cotransfection. Furthermore, Chlamydial LPS and cHSP60 also be shown to induce NF-kB transactivation in early stage by CD14-dependent manner.

更进一步，分别利用披衣菌脂多醣体和热休克蛋白六十也可以藉由CD14在早期活化NF-kB，但只有热休克蛋白六十可以像披衣菌一样，藉由TLR2而加强NF-kB活化。

Heat shock protein 22 (HSP22) is a member of small HSP subfamily.

热休克蛋白22(HSP22)是唯一在体外能以单体形式存在的小分子热休克蛋白，具有分子伴侣功能和激酶活性。

E. coli cells harboring the recombinant plasmid was cultured with Laria broth medium and induced with isopropyl β-D-thiogalactopyranoside and detected from supernatant and precipitate of culture lysates by using SDS-PAGE.

将重组菌培养并经IPTG诱导后用超声波裂解菌体，取上清和沉淀同时作SDS-PAGE电泳后显示，上清中没有热休克蛋白A的表达，在沉淀中有热休克蛋白A的表达。

Molecular dynamics simulation has been used to investigate the force-induced unfolding of mesophilic cold shock protein, finding that the unfolding process occur through intermidate states.

当使用机械力对嗜温冷休克蛋白进行拉伸研究时，发现嗜温冷休克蛋白的去折叠过程具有明显的中间态。

A detail comparison demonstrates that such preconditioned IbpB is distinguished from the non-preconditioned IbpB by a remarkable conformational transformation, including a significant increase in the flexibility of the N- and C-terminal regions, as well as enhanced dynamic subunit dissociation/reassociation.

我们的比较研究表明，这样的经过热休克预处理过的 IbpB蛋白与未经历过热休克条件的蛋白之间存在很大的构象上的差异，包括前者在N-和C-末端区域可曲性的明显增强，以及亚基动态分离/重结合的加强。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。