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The low molecular weight subunits in albumin,globulin and oryzenin all declined while...

SDS-PAGE电泳图谱显示清蛋白、球蛋白和谷蛋白的高分子量亚基含量增多,低分子量亚基含量减少,非淀粉粒蛋白与淀粉的相互作用在大米陈化过程中增加。

Unlike previous models in which overexpression of the amyloid precursor protein results in amyloid plaque formation, have produced mice that overexpress only Aβ40 or Aβ42 and prove that Aβ42 is critical for the formation of amyloid deposits in vivo.

不同于早先调控淀粉样蛋白前体蛋白的动物模型,McGowan 等(Neuron, Vol 47, 191-199, 21 July 2005)培养了专一表达Aβ40或者 Aβ42的老鼠,结果直接证明了Aβ42 确实是引起淀粉样蛋白沉淀的主要因素,而不是Aβ40。

The aim of this study was to investigate the expression of mPGES-2 protein in mouse oviduct during the early pregnancy, pseudopregnancy, and estrous cycle by immunohistochemistry and Western blot. The regulation of mPGES-2 protein in mouse oviducts was also studied under delayed implantation, steroid hormonal treatments and oviductal ligation.

本实验主要利用早期妊娠、假孕、输卵管结扎、发情周期、激素调节以及延迟着床等实验模型,结合免疫组织化学和Western blot 的实验方法,详细研究了mPGES-2 蛋白在小鼠输卵管中的表达与调节。mPGES-2 蛋白主要定位于不同时期的伞部和壶腹部的上皮纤毛细胞中,在伞部和壶腹部肌层以及峡部和宫管连接处的上皮和肌层中未检测到mPGES-2 蛋白的表达。

Results According to the treatment group, The total protein、albumin、globulin、the former albumin、serum glucose are higher than that of the control group; the Immunoglobulin (IgG、IgA、 IgM) are significantly higher than that of the control group, and the urea is significantly lower than that of the control group. Other indicators: total bilirubin、glutamic pyruvic transaminase、glutamic oxalacetic transaminase、alkaline phosphatase、creatinine、hemoglobin and the red blood cell count have no significant difference between the two groups.

结果 治疗组总蛋白、白蛋白、球蛋白、前白蛋白、血糖比对照组高;尿素比对照组明显减低;免疫球蛋白(IgG、IgA、IgM)比对照组明显升高;总胆红素、谷丙转氨酶、谷草转氨酶、碱性磷酸酶、肌酐、血红蛋白、红细胞计数等项,两组无明显改变。

Methods Male New Zealand white rabbits were exposed to pentavalent arsenate and trivalent arsenite 5 mg/L for 18 weeks, respectively. Levels of thioredoxin, protein and non-protein sulfhydryl and the activity of thioredoxin reductase and glutathione reductase in liver, and the levels of inorganic arsenic, monomethylarsonic acid and dimethylarsinic acid in blood, urine, and hair were measured after that.

家兔以自由饮水方式慢性暴露于无机3价砷及5价砷,18周后,测定肝脏组织中蛋白巯基、非蛋白巯基、硫氧还蛋白水平,以及硫氧还蛋白还原酶、谷胱甘肽还原酶活性,同时检测血、尿及毛发中无机砷及其代谢产物甲基砷和二甲基砷。

We study the express of heparinase,matrix metalloproteinase MMP-2,MMP-14 and cadherin in the gastric cancer tissue and perigastric normal mucosal tissue,and make a statistics analysis between heparinase, matrix metalloproteinase MMP-2,MMP-14,E-cadherin and gastric cancer biological behavior.We hope to knom the possibility that heparinase,matrix metalloproteinase MMP-2,MMP-14,E-cadherin are regared as clinical screen index of the gastric cancer recrudescence or metastasis.

本文就肝素酶、基质金属蛋白酶MMP-2、MMP-14、钙粘蛋白在胃癌组织及胃周正常粘膜的表达进行了研究,并就肝素酶、基质金属蛋白酶MMP-2、MMP-14、钙粘蛋白与胃癌的生物学行为进行了统计学分析,以期了解肝素酶、基质金属蛋白酶MMP-2、MMP-14、钙粘蛋白作为胃癌复发或转移的临床筛选指标的可能性。

Results The numbers of female and male of Periplaneta fuliginosa were 31 strips and 29 strips; the numbers of female and male of Periplaneta Americana were 30 strips and 28strips; the numbers of female and male of Blattella germarica were 28 strips and 25 strips.

结果黑胸大蠊的蛋白条带数目♂为29条,♀为31条;美洲大蠊的蛋白条带数目♂为28条,♀为30条;德国小蠊的蛋白条带数目♂为25条,♀为28条。

The secreted protein can reach to periplasm by the Sec-dependent system, and to export from cellular matrix by a machine composed of 12~14 proteins.

分泌的蛋白会先藉由Sec-dependent系统到达膜间质,再由一群12~14个蛋白所组成的分泌机器将分泌蛋白运送出细胞外。

In accordance with the invention, the hG-CSF protein can be prepared with high purity through rather simple process facilitating secretion of large amount of hG-CSF fusion protein into the periplasm, which does not require complicated processes such as solubilization and subsequent refolding required for isolation of the hG-CSF protein produced in cytoplasm as insoluble inclusion bodies by conventional techniques, thus, the hG-CSF protein can be widely used as an active ingredient in the development of supplementary agents for anticancer therapy.

根据本发明,通过促进大量hG-CSF融合蛋白分泌到周质中的相当简单的方法可以高纯度制备hG-CSF蛋白,所述方法不需要复杂的加工过程例如对于通过常规技术分离胞质中产生的作为不溶性包函体的hG-CSF所需的溶解和随后再折叠,因此,在开发用于抗癌治疗的补充药物的过程中可用hG-CSF蛋白广泛地作为活性成分。

Nevertheless, no homologues of typical molecular chaperones have so far been found in periplasm, and the recently reported chaperone activities of periplasmic protein disulfide isomerase and peptidyl pro-lyl isomerase seem to be too weak to satisfy such assumed needs.

虽然膜间质中的蛋白二硫键异构酶和脯氨酸顺反异构酶最近被报导具有分子伴侣活性,但是这种活性的检测使用的不是天然的膜间质蛋白,而且没有捕获到复合物的形成,因此看起来仍不能够满足前面分析的对膜间质蛋白保护的需求。

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Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

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