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蛋白

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DESCRIPTION】the ingredients of the product comes from abyssopelagic fishes of special pure and clean sea areas, adopting Limited Enzymic Degraded Technology, a self-owned intellectual property, that is using compound bioenzyme preparations at a low temperature to extract active ingredients through a special low-temperature extraction process and specific sheared protein to ensure the bioactivity of Collagen.

本品原料来自纯净、无污染的特定海域中的深海鱼类,采用具有自主知识产权的限制性酶切制备多肽技术(Limited Enzymic Degraded Technology),在低温下使用复合生物酶制剂,通过特殊低温萃取工艺提取有效成分,通过特异性的剪切蛋白质,保证了胶原蛋白原有的生物活性,并将原分子量为30万左右的胶原蛋白分子降解成3500左右的胶原蛋白多肽(约含30个左右的氨基酸残基),其分子长度降至30—50nm,集中度达到99.5%以上,呈白色或淡黄色,无异味,无杂物,不添加任何激素和化学物质,没有任何毒副作用。

Studies also indicated that genistein exsists not only in soybeans but also in many kinds of plants such as vegetables and fruits.As a potential anticancer agent, the actional mechanisms of genistein mainly includes as follows:First, genistein can depress the activity of protein tyrosine kinase and transduction pathways for the phosphorylation of receptors and mitosis signal. So genistein can lead to cells' proliferation depressed. Second, genistein has minimal effects of phytoestrogens. It can be combined with estrogen receptor and improve the synthesis of cellular sex hormone binding glulobin, and improve the activity of UDP-glucuronyl transferase. Through these pathways, it can inhibit the cell activity of breast cancer and prostate cancer.

作为一个很有潜力的抗肿瘤物质,三羟异黄酮的作用机制主要包括:①抑制蛋白酪氨酸激酶活性,可阻抑PTK引起的受体磷酸化和有丝分裂的信号传递,导致癌细胞增殖受抑;②弱雌激素作用:可通过与体内雌激素受体结合,并可增加细胞内性激素结合球蛋白的合成,增加UDP-葡糖醛酸转移酶的活性等途径抑制乳腺癌和前列腺癌细胞活性;③拓扑酶Ⅰ和Ⅱ抑制剂,抑制细胞活性;④上调细胞周期性负性调节因子P21WAF1/CIP1的表达,使之负性调节因子作用增强;⑤可阻止胰岛素样生长因子-Ⅰ、肝细胞生长因子和神经生长因子的作用而抑制肿瘤生长;⑥其他:抗氧化作用、抑制热休克蛋白、诱导细胞凋亡、抑制新生血管生成和抑制多种耐药相关蛋白等。

The results suggest the expression of Nm23-〓 Protein is more often seen in the cases of adenosis with atypical hyperplasia than in the cases of carcinoma, the expression of Nm23-〓 might be a marker of adenosis with atypical hyperplasia in cases of FCD; Lower level of Nm23-〓 suggests in had a high metastatic potentiality in breast cancer.

在浸润性导管癌组中,有腋窝淋巴结转移组的Nm23-〓含量显著低于无液窝淋巴结转移组。结果提示:Nm23-〓蛋白在不典型增生上皮中的表达比癌组织更常见,Nm23-〓蛋白过度表达可能是乳腺上皮不典型增生的一个特征;在乳腺癌病例中,Nm23-〓蛋白表达与腋窝淋巴结状态有关。

The results demonstrate that a greatly increased bioavailability of As under the flooded conditions is the main reason for an enhanced As accumulation by flooded rice, and growing rice aerobically can dramatically decrease the As transfer from soil to grain.

这两种硅运输蛋白都在根部表达,其中一种称为Lsi1的蛋白是亚砷酸盐进入水稻的门户,而另一种称为Lsi2的蛋白控制着从根部到茎再到谷粒的流动。这组研究者还发现硅酸—含有硅、氢和氧—会干扰亚砷酸盐的摄取。他们提出,增加土壤中可利用的硅,可能会减少从土壤和灌溉用水到水稻的砷的运输。(生物谷Bioon.com

Neuroglobin, a recently identified monomer globin in nerve system, is highly affinitive with oxygen similar to myoglobin. After the coding region of rat NGB gene was sub cloned into the prokaryotic expression vector pGEX 4T 2, the recombinant vector was introduced into E. coli BL21 (DE3) cells for efficient expression.

氧是人类及许多生物赖以生存的重要条件,严重缺氧和低氧可危及人体生命。2 0 0 0年 9月,德国Burmester等人首次报道了人和小鼠脑内存在特异的功能上类似于肌红蛋白的携氧蛋白———脑红蛋白(neuroglobin ,NGB) [1 ] 。

Staining for agrin, the major HS proteoglycan core protein in the GBM, was unaltered.

而GBM内主要的HS蛋白多糖核心蛋白—集聚蛋白染色没有变化。

Modification of soy protein concentration was studied under the condition of heating , shearing and alkalescent.

本文在加热、剪切和弱碱条件下对醇法浓缩蛋白的改性进行了研究,结果表明,大豆浓缩蛋白经过改性后能拓宽大豆浓缩蛋白在食品工业中的应用及达到人们所希望的功能特性。

Results (1) The degrees of alveolitis and pulmonary fibrosis of the model group was increased remarkably on day 7,14,28 compared with the control group (P.05), The expression of TNF-α, TGF-β1, FN protein of model group on day 7, 14, 28 was remarkably increased compared with the control group (P.05);(2)The degrees of fibrosis and the expression of TNF-α, TGF-β1 , FN protein are decreased significantly in Group B compared with Group A( P.05) but not significantly in Group C.

结果:(1)模型组肺泡炎、肺纤维化程度都明显重于对照组,肺泡炎、肺纤维化第7、14、28d差异显著(P<0.05);TNF-α、TGF-β_1、FN蛋白表达明显上调(P<0.01);(2)治疗组B组第7、14、28d肺泡炎、肺纤维化程度较模型组明显减轻,TNF-α、TGF-β_1、FN蛋白表达明显下调(P<0.05):(3)治疗组C组第28d肺泡炎、肺纤维化程度与模型组相似,TNF-α、TGF-β_1、FN蛋白表达与A组比较无统计学意义(P>0.05)。

To realize the molecular compositions and bio-spinning mechanisms of spidroin in spider major ampullate, the molecular weight and amino acid compositions of spidrion solution were measured and compared with that of dragline silk. The molecular conformations and morphologies of spidroin and dragline silk in different spinning phases were determined by circular dichroism spectroscopy and laser Raman spectroscopy.

本文以广泛分布于我国各地的大腹园蛛为对象,研究了大腹园蛛主腺体内丝蛋白溶液的分子量和氨基酸组成,并利用圆二色光谱和拉曼光谱分析了蜘蛛在不同成丝阶段丝蛋白的分子构象和聚集态结构的变化,以期了解蜘蛛主腺体内丝蛋白的分子组成及其生物纺丝机制。

This study separated high quality of steel and high elastic silk gene of major ampullate gland and flagelliform gland of Aranbeus ventricosus,and saparated mRNA ,and published several new gene of silk protein for AvF1(AY174110),AvF2(AY177203),AvFf1(AY587193) in GeneBank.

通过鸟枪法、Southern杂交等方法筛库,在没有借鉴国外丝蛋白基因的基础上,获得具有自主知识产权的蛛丝蛋白mRNA,并将蛛丝蛋白AvF1(AY174110)、AvF2(AY177203)、AvFf1(AY587193)等多个新基因登录GenBank。

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