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Besides, we also found that NOD2 could participate in down-regulation of macrophage bactericidal activity and TLR4-induced LC3 activation.

在另外的实验中,我们也发现NOD2蛋白能够负向调控巨噬细胞的杀菌能力以及TLR4所引发的LC3蛋白的活化(是一个细胞自噬的标志蛋白)。

Also there was no significant correlation between the levels of APRIL and BAFF proteins.

疾病组外周循环中BAFF蛋白显著升高,APRIL蛋白未见升高,APRIL和BAFF之间未见显著意义相关性,APRIL蛋白与抗-dsDNA和疾病活动度之间未见显著相关。

Results: The numbers of Bombesin positive pulmonary cells, the lamina propria S-l00 protein, neuron-specific enolase positive nerve fibers, IgE positive cells, mast cells and IgE positive mast cells significantly increased in bronchiectasis. The changes of pulmonary endocrine cells, nerve fibers and IgE positive cells were more significantly in hyperplastic BALT areas. The S-100 and NSE were found in lymphoid tissue and BALT. A close contact was found between mast cells and the S-100 positive nerve fibers. An IgE positive outer zone was found on MC surface. Mast cells and IgE positive cells were seen in the bronchial epithelium and alveolar septa.

结果:支气管扩张症中,支气管上皮蛙皮素阳性细胞、固有膜S-100蛋白和神经特异性烯醇化酶阳性神经纤维、IgE阳性细胞、MC和IgE阳性MC均显著增多,且在支气管相关淋巴组织增生的区域上述肺内分泌细胞、神经纤维和IgE阳性细胞增多尤为显著,S-100蛋白和NSE阳性神经纤维分布於弥散淋巴组织和BALT中,MC与S-100蛋白阳性神经纤维紧密接触,MC表面有IgE阳性环状带,MC和IgE阳性细胞出现在支气管上皮间和肺泡壁。

Methods Determine the marker of hepatitis B by ELISA, total protein by biuret method, albumin by bromocresol green method, and the component of serum protein by agarose gel electrophoresis.

采用酶联免疫吸附实验检测乙肝标志物,双缩脲法检测总蛋白,溴甲酚绿法检测白蛋白,琼脂糖凝胶电泳法分析血清蛋白组分。

The wool polyester soybean protein fiber are blent for making shirting fabrics combining characteristic of wool and soybean protein fiber .

结合羊毛和大豆蛋白纤维各自优良的性能,采用羊毛纤维,涤纶,大豆蛋白纤维混纺,开发出高档大豆蛋白纤维衬衣面料。

The profile of liver CYP450 induction by DEX in male rat After 4 daily i.p. administering of 0,25, 50 and lOOmg/kg/d DEX in male Wistar rat, it was determined the total CYP450 content, the mRNA and protein expression levels of CYP3A1, CYP3A2 and CYP2B1/2, and the ERD (CYP3A catalytic activity), PROD (CYP2B catalytic activity) and BROD (total CYP450 catalytic activity) in livers.

DEX对雄性大鼠肝脏CYP450的诱导效应雄性Wistar大鼠腹注0、25、50和100mg DEX/kg/d诱导处理4天后,测定大鼠肝脏总CYP450含量,CYP3A1、CYP3A2和CYP2B1/2的mRNA及蛋白表达水平,肝脏红酶素脱甲基酶(ERD,CYP3A活性),苄氧基试卤灵脱乙基酶(PROD,CYP2B活性),苯氧基试卤灵脱乙基酶(BROD,总CYP450活性),结果表明,CYP450含量、ERD、PROD和BROD在DEX多次诱导后都有升高,CYP3A1 mRNA表达水平、蛋白含量和酶活性有明显的升高,剂量效应关系明显;CYP3A2蛋白也有明显升高,而其mRNA表达水平却没有变化,提示CYP3A1和CYP3A2的诱导机制可能不同。

The profile of liver CYP450 induction by DEX in male ratAfter 4 daily i.p. administering of 0,25, 50 and lOOmg/kg/d DEX in male Wistar rat, it was determined the total CYP450 content, the mRNA and protein expression levels of CYP3A1, CYP3A2 and CYP2B1/2, and the ERD (CYP3A catalytic activity), PROD (CYP2B catalytic activity) and BROD (total CYP450 catalytic activity) in livers.

DEX对雄性大鼠肝脏CYP450的诱导效应雄性Wistar大鼠腹注0、25、50和100mg DEX/kg/d诱导处理4天后,测定大鼠肝脏总CYP450含量,CYP3A1、CYP3A2和CYP2B1/2的mRNA及蛋白表达水平,肝脏红酶素脱甲基酶(ERD,CYP3A活性),苄氧基试卤灵脱乙基酶(PROD,CYP2B活性),苯氧基试卤灵脱乙基酶(BROD,总CYP450活性),结果表明,CYP450含量、ERD、PROD和BROD在DEX多次诱导后都有升高,CYP3A1 mRNA表达水平、蛋白含量和酶活性有明显的升高,剂量效应关系明显;CYP3A2蛋白也有明显升高,而其mRNA表达水平却没有变化,提示CYP3A1和CYP3A2的诱导机制可能不同。

Inflammatory cell infiltration and bronchiolitis severity were significantly reduced ofter administration of E. globulus oil. Especially in 300 mg·kg -1 treated rats,there were significant decreases of mucin content in BALF and MUC5ac expression in trachea and bronchiole epithelium. Optical density and mucins area% detected by image analysis system were apparently lower than those in model group. Conclusion: E.

各给药组经不同浓度蓝桉油灌胃后能减少中性粒细胞及淋巴细胞的浸润,降低炎症程度;尤其是蓝桉油高剂量组(300 mg·kg-1),能明显减少灌洗液中黏蛋白含量,使气管和细支气管上皮内黏蛋白MUC5ac表达的阳性染色区域和程度明显减轻,通过图像分析系统测得的吸光度值和黏蛋白面积%均明显低于模型组。

Result The background noise of bidirectional electrophoresis map of protein extracted by TCAJA method was greater, its clarity was poor, its horizontal striations were more and there were tinny spots with irregular shape appeared on it. The variegated spots had difference from the normal protein spots, they formed high coverage and shading on the other protein spots and affected the accurate expression of map information. The background noise of bidirectional electrophoresis map of protein extracted by Trizol method was little, its horizontal striations and non-protein impurities were less, there was no shading phenomenon strong spots and mere protein spots, so it provided abundant information for quantitative and qualitative analyses on the proteome from buffalo grass seeds, Compared with TCA/A precipitation.

结果]TCA/A法提取的蛋白质双向电泳图谱背景噪音大,清晰度差,横向条纹较多,图谱上呈现多个形状不规则的斑点,杂色与正常蛋白质点有区别,对其他蛋白质点构成高度及盖和遮进,影响图谱信息的准确表达;Trizol法所提取的蛋白质样品,其双向电泳图谱背景嗓音小,横向条纹少,非蛋白类杂质少,无斑点间的这进现象,蛋白质点数量增多,为野牛草种于蛋白质组定量、定性分析提供了丰富的信息。

Gotoh Y, Nishida E, Yamashita et al. Microtubule associated protein kinase activated by nerve growth factor and epidermal growth factor in PC12 cells: identity with the mitogen-activated protein kinase of fibroblastic cells. Eur J Biochem, 1990, 349: 661~669.[7]Cook SJ, Beltman J, Cadwallader KA et al.

本文观察到,在AngⅡ介导的心肌细胞肥大反应中,伴随着MAPK的激活, MKP-1蛋白表达增加,若以AT1受体阻断剂CV11974或MAPK激酶特异性抑制剂PD098059抑制MAPK激活,同时也抑制了MKP-1蛋白表达,提示MAPK的激活可能是MKP-1蛋白表达的诱导因素之一。

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I didn't watch TV last night, because it .

昨晚我没有看电视,因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来,在北京的很多小区里,电梯液晶电视被撤了下来。

I'm running my simile to an extreme.

我比喻得过头了。