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We hypothesized that the intrathecal administration of veratridine, a drug that enhances the activity or effect of sodium channels, should increase MAC.

我们假定蛛网膜下腔注射藜芦定能增加钠通道的活性和效应则会增加 MAC 值。

The results suggest that veratridine and aconitine induce different firing patterns in injured DRG neurons, which may relate to their inhibitory effects on different binding sites of the sodium channel.

实验结果表明,藜芦碱和乌头碱在受损的背根节神经元可以引发不同的放电模式,这可能与它们结合于钠通道上不同位点的抑制作用有关。

OBJECTIVE: To observe the characteristics of epileptiform activities of rat hippocampal CA1 pyramidal neurons induced by low-dosage veratridine and investigate its possible ion mechanism.

目的:观察小剂量藜芦碱诱发大鼠脑海马CA1区锥体神经元产生癫痫样活动的特征,探讨其可能的离子机制。

A specific bursting, parabolic bursting induced by veratridine, has been observed in rat injured sciatic nerve.

在大鼠受损坐骨神经上加入 5 μmol L藜芦碱溶液,观察到了抛物线簇放电的现象。

The firing patterns induced by veratridine and aconitine, inhibitors of inactivation gate of sodium channel operating on different binding sites, were compared.

藜芦碱和乌头碱是钠通道失活门的抑制剂,但二者作用于不同的位点,前者结合于D2-S6,后者结合于D3-S6。我们比较了这两种试剂引发的放电模式。

The slow sodium influx educed by veratridine and the calcium-dependent potassium outflux are regarded as the two slow variables, which are responsible for the parabolic bursting.

结合实验模型,从离子通道活动的角度揭示了抛物线簇放电发生的生物物理机制。由藜芦碱诱发的慢变钠内流和钙依赖钾外流被认为是引发实验所观察到的抛物线簇放电的两个慢变量。

The effects of phenytoin (2.5, 5, 10 and l5 μmol/L) and gabapentin (2.5, 5 and l0μ mol/L) on the epileptiform activity were observed under the volt age- clamp configuration. and the current changes for 1 hour in CA I neurons was also observed. Results Nine-sixteen minutes after veratridine perfusion, the huge.

分别在电压钳模式下观察2.5、5、10、15μmol/L苯妥英和2.5、5、10μmol/L加巴喷丁对这种癫痫活动的影响;测定藜芦碱灌流后CA1锥体神经元Ih电流的变化规律。

However, the role of inactivation gate of sodium channel is not clear. In present study, single fibre recording in vivo from dorsal root on chronically compressed DRG model was used. We analyzed the characters of ISI series of oscillation firing of type A neurons induced by veratridine, an inhibitor of inactivation gate of sodium channel.

本研究在大鼠背根节慢性压迫模型上,利用在体单纤维记录方法,观察与分析Na通道失活门抑制剂藜芦碱引起受损背根节A类神经元放电ISI序列发生的变化特征,为了解Na通道失活门与放电型式的关系以及进一步探索放电时间型式与疼痛的关系奠定基础。

Low-dosage veratridine may induce runs of PDS like epileptiform activities on rat CA1 pyramidal neurons.

小剂量藜芦碱可在大鼠脑海马CA1区锥体神经元上诱发出阵发性去极化漂移样癫痫活动。

Recertly, the intrinsic nature of PDS has received more attention.OBJECTIVE: To observe the characteristics of epileptiform activities of rat hippocampal CA1 pyramidal neurons induced by low-dosage veratridine and investigate its possible ion mechanism.

近年来,阵发性去极化漂移的内因机制得到进一步关注和重视。;目的:观察小剂量藜芦碱诱发大鼠脑海马CA1区锥体神经元产生癫痫样活动的特征,探讨其可能的离子机制。

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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?