蒂巴因

Allison Abbate, Colleen Atwood, John August, Rick Baker, Helena Bonham Carter, Felicity Dahl, Johnny Depp, Danny Devito, Danny Elfman, Carlos Grangel, Ray Harryhausen, Martin Landau, Rick Heinrichs, Christopher Lee, Lindsay Macgowan, Shane Mahan, Ian Mackinnon, Alex Mcdowell, Victoria Price, Ken Ralston, Paul Reubens, Deep Roy, Winona Ryder, and Richard Zanuck.

阿利森阿巴特，科琳阿特伍德，约翰奥古斯特，瑞科贝克，海伦娜邦汉卡特，富临达尔，约翰尼德普，丹尼德维托，丹尼叶夫曼，卡洛斯Grangel，雷·哈里豪森，马丁兰道，里克海因里希斯，克里斯托弗李，林赛麦高恩，巴蒂尔马汉，伊恩麦金农，亚历克斯道尔，维多利亚价格，拉尔斯顿，保罗鲁宾斯，深罗伊，薇诺娜瑞德，和理查德扎纳克。

Germany's vice-captain and Bayern Munich midfield star Bastian Schweinsteiger likes to be last to arrive at the stadium.

德国队副队长、拜仁慕尼黑俱乐部明星中场球员巴斯蒂安·施魏因斯泰格喜欢最后一个到达球场。

Canadian French explorer Jean Baptiste Le Moyne Sieur de Bienville landed on the tip of what is now Louisiana in 1699 an area 60 miles south of the current New Orleans which he named Pointe due Mardi Gras.

"加拿大的法国探险家让巴蒂斯特莱莫因开拓者宾维尔降落在路易斯安那州的东西现在在1699年，一个地区以南60英里目前新奥尔良，他命名为"特因狂欢节的一角。

In this thesis, synthetic process route for natrexone hydrochloride was studied from the laboratory aspect. The target compound, natrexone hydrochloride, was synthesized via preparing intermediate, methylnaltrexone, using thebaine as starting material.

本论文从试验方面研究了由蒂巴因出发，中间合成甲基纳曲酮中间体，最后制备盐酸纳曲酮的合成工艺路线。

Then the promoter CaMV 35S driven, plant siRNA expression vector pARB with inverted repeats of BBE was constructed based on the vectors pHANNIBAL and pART27. The work will lay the foundation for breeding a low morphine and high thebaine poppy.

以中间载体pHANNIBAL和植物表达载体pART27为基础，构建了CaMV-35S启动子驱动的含小檗碱桥酶基因片段反向重复序列的RNAi双元表达载体pARB，为培育低吗啡，高蒂巴因的罂粟新品系奠定了基础。

Then the promoter CaMV 35S driven, plant siRNA expression vector pARB with inverted repeats of BBEwas constructed based on the vectors pHANNIBAL and pART27. The work will lay the foundation for breeding a low morphine and high thebaine poppy.

以中间载体pHANNIBAL和植物表达载体pART27为基础，构建了CaMV-35S启动子驱动的含小檗碱桥酶基因片段反向重复序列的RNAi双元表达载体pARB，为培育低吗啡，高蒂巴因的罂粟新品系奠定了基础。

The cloned BBE gene sequences were 94.84% identified with the reported BBE genes in GenBank previously. Based on the cDNA sequences of COR and BBE ,two fragments about 400～500 bp from each gene with lower identity among them were cloned. The fusion gene BC (744 bp) is fused by the PCR technique. Then the promoter CaMV 35S driven, containing'forward BC fusion fragments-reverse pdk intron-reverse BC fusion fragments', plant siRNA expression vector were constructed based on the vectors pHANNIBAL and pART27.The work will lay the foundation for breeding a low morphine and high thebaine poppy.

利用blast及分子生物学软件DNAStar对COR和BBE基因的cDNA序列同源性进行分析比较，分别从各基因中筛选和克隆了一段同源性极低、约400～500 bp的片段；并应用重叠PCR法将其拼接成744 bp的融合基因BC，以中间载体pHANNIBAL和植物表达载体pART27为基础，构建了以CaMV 35S启动子驱动的含有"正向BC融合片段- pdk内含子-反向BC融合片段"的ihRNAi植物表达载体，通过转化野生罂粟，初步研究了以COR和BBE基因为靶标的RNAi对内源吗啡合成的抑制效果，为进一步培育低吗啡高蒂巴因的罂粟种质提供了依据。

In the process of laboratory study, oxycodone was prepared by oxidating thebaine at 6,14-position under oxydol, hydrodeoxidizing 7,8-position double bond and 14-position ether under palladium catalyst. Furthermore, N-methyl of oxycodone was isolated byα-chloro-ethyl chloroformate under anhydrous condition and protection of 14-position hydroxyl to obtain noroxycodone, which was further converted into methylnaltrexone by N-alkylation in presence of cyclopropyl bromomethane, then by isolating 3-position methyl of methylnaltrexone under boron tribromide, becoming hydrochloride to prepare target compound, natrexone hydrochloride.

实验室工艺方面，本文首先用双氧水氧化蒂巴因的6-位和14-位、在钯炭催化下加氢还原7-8位双键和14-位醚合成羟考酮，然后提出并优化了在无水和14-位保护的情况下，用氯甲酸-α-氯乙酯脱去羟考酮的N-位甲基合成去甲羟考酮，再用环丙甲基溴将去甲羟考酮的N-位烷基化合成甲基纳曲酮，最后采用三溴化硼脱去甲基纳曲酮的3-位甲基和成盐酸盐合成盐酸纳曲酮。

Gueli meters, Sanchez, carrasco, Schuster,乌鲁蒂, Maradona, Zubizarreta, Lineker, Vaquero, Kibaki agency,阿摩尔, Farmer and Labor Laudrup, Ferrer, Stoichkov, Guardiola, Romario, Sergi,阿贝拉多, Ronaldo, Luis.

米圭利，桑切斯，卡拉斯科，舒斯特尔，乌鲁蒂，马拉多纳，苏比萨雷塔，莱因克尔，巴克罗，贝吉里斯坦，阿摩尔，科曼，劳德鲁普，费雷尔，斯托伊奇科夫，瓜迪奥拉，罗马里奥，塞尔吉，阿贝拉多，罗纳尔多，路易斯。

This paper introduces the studies of Gerhard Ertl, who is awarded the Nobel Prize in Chemistry 2007, in adsorption of hydrogen on metal surfaces, the mechanism of catalytic reaction in Haber- Bosch process for synthesis of ammonia, and the process of catalytic oxidation of CO.

格哈德·埃特尔的重要贡献主要有3方面：(1)解决了氢原子是如何在Pd、Pt和Ni等金属表面组织排列的问题；(2)对哈伯一博施法合成氨反应催化机理的研究；(3)对C催化氧化的研究及非线性动力学理论的建立。1 氢在金属表面吸附的研究萨巴蒂埃因发现精细金属颗粒催化有机物加氢的方法而获1912年度诺贝尔化学奖。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。