葡萄胎

Methods: The expression of survivin in the trophocyte of 14 cases of normal early gestation villi, 14 cases of hydatidiform mole, 12 cases of invasive hydatidiform mole and 12 cases of choriocarcinoma were detected by immunohistochemistry test.

采用免疫组化SP法检测14例正常早孕绒毛、14例葡萄胎、12例侵蚀性葡萄胎及12例绒癌滋养细胞中survivin的表达。

Objective This study was conducted to detect the expression of laminin and laminin receptor in the specimens of hydatidiform mole, invasive mole and choriocarcinoma, respectively.

目的 了解葡萄胎、侵蚀性葡萄胎和绒毛膜癌组织中层粘连蛋白及其受体的表达，并探讨LN、LN-R与妊娠滋养细胞肿瘤侵袭和转移的关系。

MATERIALS AND METHODS: The protein expressions of MMP-7 and MMP-9 were evaluated by immunohistochemistry in 18 normal villi. 49 hydatidiform moles, in which 8 were malignantly transformed moles.

材料与方法：采用免疫组织化学PV-6000法测定49例葡萄胎（其中8例恶变，列为葡萄胎恶变组）和18例正常绒毛组织中的MMP-7和MMP-9蛋白表达量。

Results The expression of CD146 was remarkably elevated in malignantly transformed mole than that in normal villi and non- malignant transforming mole （P〈0.01 respectively）,the sensitivity and specificity of CD146 in predicting malignant transformation of complete hydatidiform mole was 71.05% and 78.57% respectively.

结果完全性葡萄胎恶变者CD146的表达较正常胎盘绒毛和完全性葡萄胎未恶变者显著增强（P均〈0.01）；CD146预测完全性葡萄胎恶变的敏感度和特异性分别为71.05％和78.57％。

Methods Immunohistochemical streptavidin-peroxidase method was used to detect the expression of MMP-2, MMP-9, TIMP-1, TIMP-2 in 20 cases of normal human cytotrophoblast cells,15 cases of partial hydatidiform moles, 55 cases of complete hydatidiform moles, 15 cases of invasive moles and 8 cases of choriocarcinoma.

应用链霉菌抗生物素蛋白-过氧化物酶免疫组织化学方法对20例正常早孕(2周)绒毛组织、15例部分性葡萄胎、55例完全性葡萄胎、15例侵蚀性葡萄胎、8例绒毛膜癌组织中MMP-2、MMP-9、TIMP-1、TIMP-2进行检测。

In GTD, there were no significant relationship between the normal expression of Ecad and the strong expression of LN.

在葡萄胎、侵蚀性葡萄胎及绒毛膜癌中Ecad的正常表达率分别为53.3%、31.25%和16.67%；LN的强表达率分别为80%、56.25%和50%。

In HM, IM and CC, the normal expression rates of Ecad were 53.3%, 31.25% and 16.67%, respectively; the strong expression rates of LN were 80%, 56.25% and 50%, respectively.

在葡萄胎、侵蚀性葡萄胎及绒毛膜癌中Ecad的正常表达率分别为53.3%、31.25%和16.67%；LN的强表达率分别为80%、56.25%和50%。

Methods The expressions of PCNA were checked by means of immunohistochemistry in the tissue of hydatidiform mole of 32 cases.

葡萄胎组织32例，应用免疫组织化学方法染色检测葡萄胎组织的PCNA表达。

Expression of osteopontin and matrix metalloproteinase-2 were detected in 40 normal placentas ,15 cases with hydatidiform moles by immunohistochemistry technique.

应用免疫组化方法分别检测正常早孕妇女绒毛40例(6周、7周、8周、9-12周各10例)、葡萄胎20例(完全性葡萄胎15例、部分性葡萄胎5例，均12周)组织中骨桥蛋白和MMP-2的表达情况，并采用病理图象分析技术进行半定量分析。

Distinction of hydatidiform moles from nonmolar specimens and subclassification of HMs as complete hydatidiform mole, partial hydatidiform mole, or early CHM are important for clinical practice and investigational studies but diagnosis based solely on morphology suffers from poor interobserver reproducibility.

鉴别葡萄胎和非胎块性病变、HM亚型（完全性葡萄胎CHM、部分性葡萄胎PHM、早期完全性葡萄胎eCHM），这对于临床实践和调查研究都十分重要。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷