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The severity of staphyloma formation is correlated with conus formation,high myopia,and ocular elongation.

B超是诊断巩膜后葡萄肿最安全、快速、可靠的方法,对近视眼的预后判断有着重要作用。

Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome

目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析,并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography,FFA)、吲哚青绿血管造影(indocyanine green angiography,ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例,73.5%),双眼同时患病118例(80.8%);后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%);前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例,98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%);后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障;毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现;炎症活动期FFA典型表现为斑驳状高荧光,ICGA发现脉络膜血管扩张、通透性增高等改变;VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎,随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。

It seems that the excessive axial length of pathologic myopic eye does not get worse with age. Except the posterior staphyloma and the geographic chorioretinal degeneration.

4病理性近视眼眼轴的过长似乎不随著年龄的增大而恶化,而徒极葡萄肿和地图状脉络视网膜变性随著年龄的增大而恶化。

Aside from a diffuse chorioretinal atrophy of the posterior poles in both eyes, direct visualization of the orbital vessels was made through a posterior staphyloma in the right eye.

经眼底检查发现,除了双眼后极有广泛的视网膜及脉络膜的退化之外,患者右眼后葡萄肿里可以直接看见眼窝的血管。

A dome-shaped macula within a myopic staphyloma is an unreported type of myopic posterior staphyloma.

近视性后葡萄肿中的圆顶状黄斑是一种未曾被报道过的类型。

The dome-shaped appearance of the macula was visible on both B-scan ultrasonography and OCT: a characteristic bulge of the macular retina, RPE, and choroid within the concavity of the moderate posterior staphyloma was present in all eyes.

黄斑的圆顶状形态在B型超声和OCT中均可见:一种特征性的中度后葡萄肿凹面中黄斑区视网膜、视网膜色素上皮细胞和脉络膜膨出,这种特征可见于所有眼。

Purpose: To describe a phenomenon in which retrobulbar blood vessels were seen through a posterior staphyloma in a pathologically myopic eye. Method: Observational case report. Case Report: 71 year-old pathologically myopic female with pseudophakia presented to our clinic with a complaint of blurred vision.

目的:叙述一例病态性近视眼中葡萄肿里可见之眼球后血管方法:观察性病例报告个案报告:71岁双眼伪晶体且患有病态性近视的女性因主诉右眼模糊前来就医。

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