葡萄状的

Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome

目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析，并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography，FFA)、吲哚青绿血管造影(indocyanine green angiography，ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例，73.5%)，双眼同时患病118例(80.8%)；后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%)；前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例，98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%)；后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障；毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现；炎症活动期FFA典型表现为斑驳状高荧光，ICGA发现脉络膜血管扩张、通透性增高等改变；VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎，随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。

Leaves adaxially with sparse arachnoid tomentum when young, then glabrescent; branchlets and inflorescence axis with sparse arachnoid tomentum.

幼时的正面的叶具具稀疏蛛丝状毛，后脱落有具稀疏蛛丝状毛的小枝和花序轴。 32 V。 bellula 美丽葡萄

Follow-up of 12 revealed that 7 patients died of disease within 3 weeks to 1 year and 4 months after diagnosis, 3 died of unknown causes, and 2, both adjuvant therapy treated botryoid RMS in young children, were alive without disease 11 and 27 years later.

所有患者都切除了胆囊，并接受了6种已知的辅助性治疗。12例患者的随访信息如下：其中7例在确诊后的3周至1年4个月内死于本病，3例死亡原因不明，另外2例葡萄状RMS的儿童，接受辅助治疗，11年和27年之后仍健在且无再发本病。

Primary Gallbladder Sarcoma: A Clinicopathologic Study of 15 Cases, Heterogeneous Sarcomas With Poor Outcome, Except Pediatric Botryoid Rhabdomyosarcoma

胆囊原发性肉瘤：15个病例的临床病理分析，异质性肉瘤预后差，除了儿童的葡萄状横纹肌肉瘤

The results showed that at the anaerobic phase, the PHB concentration in the cell and orthophosphate concentration of the anaerobic effluent obviously increased, the poly-P concentration in the cell decreased, and the cucci and bacilli with a size of 1.0~1.5 μm were dominant and formed grapy cellular cluster. At the anoxic phase, the PHB concentration and orthophosphate concentration decreased significantly, the amount of poly-P increased, and the elliptical cucci of 0.5~1 μm and spheral bacilli of 1.0~1.5 μm were dominant. At the aerobic phase, the PHB and orthophosphate concentration almost reduced to zero, the poly-P increased significantly, cucci appeared single or in pair, and the contour of sphere was blur and almost disappeared.

试验结果表明，在厌氧阶段，微生物细胞内PHB的量大幅提高，上清液中磷酸盐的含量上升，聚磷酸盐含量明显下降，粒径为1～1.5 μm、呈球状和棒状的菌群构成的葡萄状细胞簇占居优势；在缺氧阶段，微生物细胞内PHB的量下降，上清液中磷酸盐含量下降，聚磷酸盐含量上升，粒径为0.5～1 μm的椭球菌与1.0～1.5 μm的球杆菌占优势；在好氧阶段，微生物细胞内PHB的量较低或接近零，上清液中磷酸盐的含量接近零，聚磷酸盐含量明显上升，此时粒径1.0～1.5 μm的球菌以单个或成对出现，球菌不再饱满，呈现接近消失的状态。

Results When the culture medium was supplemented with 0 .05μg/ml sodium selenite,the proliferation of transformed cells was significant ly promoted and the transformation did not change remarkably,when supplemented w ith 0.25μg/ml,the proliferation was promoted but the transformation was inh ibited,and when with 0.75μg/ml and 1.50μg/ml,the proliferation was not pro moted and the transformation was strongly inhibited.Big dose of (1.50μg/ml) sodium selenite m ade the nuclei of the untransformed lymphocytes gather together like a few grape s doing,and even caused them to fuse.

结果 在培养物中添加0.05μg/ml亚硒酸钠能显著促进转化细胞增殖；添加0.25μg/ml可促进转化细胞增殖，但显著抑制细胞转化；添加0.75μg/ml和1.50μg/ml，不仅不能促进细胞增殖，而且强烈抑制细胞转化。1.50μg/ml剂量的亚硒酸钠使非转化淋巴细胞发生葡萄状聚集甚至核融合。

In noninfectious uveitis (28.3%), stippled, globular, and multiple globular types of KPs were found.

非感染性葡萄膜炎（28.3%）的角膜后沉着物的特征是斑点状的、球形的以及多球形的。

Stems unarmed, sometimes with conspicuous lenticels, or bark sometimes shredding; branches often swollen at 3-7-lacunar nodes; pith continuous or interrupted by diaphragms at nodes; tendrils simple, bifurcate to trifurcate, or 4-12-branched, usually leaf-opposed, rarely tendrils absent.

茎无刺，有时有明显的皮孔，或者树皮有时碎片状（在大多数葡萄属的种里；分枝通常在3-7节腔隙膨胀；髓连续或在节上被膈膜间断；卷须单，二叉对三叉，或者4-12分枝(在Parthenocissus)，通常对生，很少无卷须。

Results Angiography showed that the bladder-like filling defect Botryodes7 cases, bladder trigone large lobulated filling defect in 1 cases of video, 5 cases of bladder wall. Four cases of bladder CT examination showed typical grape cluster-shaped cavity below the abdominal wall muscles and soft tissue density mass, partial bladder wall thickening, enhanced scan showed lesions with mild to moderate strengthening.

结果 造影显示膀胱内葡萄簇状充盈缺损7例，膀胱三角区大的分叶状充盈缺损影1例，5例膀胱壁毛糙。4例CT检查均显示膀胱腔内典型葡萄簇状低于腹壁肌肉密度软组织肿块，局部膀胱壁增厚，增强扫描病灶呈轻中度强化。

FLUFFY, dome-shaped, dotted with sultanas and candied citrus peel, panettone is an Italian Christmas cake.

松软，表面星布无子葡萄和柑橘皮蜜饯，圆顶状的潘妮托妮是意大利的一种圣诞蛋糕。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失